Results 131 to 140 of about 19,601 (224)

CDR3 Spectratyping [PDF]

, 2020
openaire   +1 more source

T cell clonality and characteristics of CDR3 sequences in TCR clonotypes bearing AV18-1 and BV8-2.

, 2013
T cell clonality was analyzed by CDR3 size spectratyping and nucleotide acid sequences were determined in TCR clonotypes bearing AV18-1 and BV8-2. RNA was extracted from footpads of Pd-induced allergy mice at 7 days (n=5) and nucleotide acid sequences of
Hiroshi Kobayashi (23858), Kazutaka Kitaura (381797), Mitsuko Kawano (466015), Kouetsu Ogasawara (466017), Satsuki Suzuki (381800), Kenichi Kumagai (381801), Takanori Eguchi (393518), Hiroaki Shigematsu (466014), Ryuji Suzuki (1641), Takaji Matsutani (381798), Yoshiki Hamada (307288), Tatsuya Horikawa (466016)   +11 more
core   +1 more source

CDR3 junction features.

, 2015
MS patient-derived repertoire is enriched for TCR sequences with long VJ insert, partially due to high abundance of specific Variable segment regions. A.
Olga V. Britanova (830791), Mikhail V. Pogorelyy (692797), Ivan V. Zvyagin (830793), Dmitriy V. Bagaev (830788), Vitalina I. Kirgizova (830794), Mikhail Shugay (113968), Elena V. Skorobogatova (830796), Vadim I. Nazarov (692794), Ekaterina V. Putintseva (830792), Maria A. Turchaninova (830789), Kirill I. Kirgizov (830795), Dmitriy A. Bolotin (830790), Dmitriy M. Chudakov (208669)   +12 more
core   +1 more source

T-cell receptors that are k-binding have defined sequence features

Frontiers in Immunology
Previous studies have revealed that individual T cell receptors (TCRs) can recognize a diverse set of peptide targets displayed by Major Histocompatibility Complexes (MHCs) to enable effective adaptive immune surveillance.
Hyunjin Park, Jonathan Krog, Jonathan Krog, Brandon Carter, Pallavi A. Balivada, Pallavi A. Balivada, Emily M. Pogue, Emily M. Pogue, Samyuktha Anand, Michael E. Birnbaum, Michael E. Birnbaum, David K. Gifford, David K. Gifford   +12 more
doaj   +1 more source

Systematic characterization of immunoglobulin loci and deep sequencing of the expressed repertoire in the Atlantic cod (Gadus morhua)

BMC Genomics
Background The Atlantic cod is a prolific species in the Atlantic, despite its inconsistent specific antibody response. It presents a peculiar case within vertebrate immunology due to its distinct immune system, characterized by the absence of MHCII ...
Ádám Györkei, Finn-Eirik Johansen, Shuo-Wang Qiao   +2 more
doaj   +1 more source

(The) CDR3 length variation of immunoglobulin k light chain expressd in peripheral blood lymphocyte of normal individuals

, 1995
의학과/석사[한글] 면역글로불린의 상보성 결정부위(complementarily determining region, CDR)는 전형적인 항원결합부위로서 이 부위의 구조적 변화는 항원의 특이성, 항원항체의 결합력 등에 변화를 일으킬 수 있는 중요한 부위로 알려져 있으며 이 중 제3 상보성 결정부위(CDR3)는 항원결합부위의 중앙에 위치한다.
송준현
core  

H-chain CDR3 contribution in specificity of autoantibodies [PDF]

Arthritis Research & Therapy, 2001
openaire   +1 more source

Alanine scan mutagenesis in CDR3 of 125-2H

, 2002
The murine antibody, 125-2H, is a potent neutralizer of interleukin (IL-18), which is associated with inflammation. Because of its murine origins it is not a clinical candidate, but its IL-18 neutralizing potency is the standard to which human monoclonal
Popinchalk, Samuel Paul
core  

TCR-alpha CDR3 loop audition regulates positive selection.

, 2006
How positive selection molds the T cell repertoire has been difficult to examine. In this study, we use TCR-beta-transgenic mice in which MHC shapes TCR-alpha use.
Dyson, J., Simpson, E., Furmanski, A., Ferreira, C., Lees, R., Guillaume, P., MacDonald, H.R., Millrain, M., Bartok, I.   +8 more
core  

Unfavourable H-CDR3 Loops in preB Cells Lead to Highly Expanded Plasma Cell Clones. [PDF]

Eur J Immunol
Aranburu A, Engström E, Demitz-Helin E, Scheffler JM, Camponeschi A, Sundell T, Ni Z, Mårtensson IL.   +7 more
europepmc   +1 more source