Results 121 to 130 of about 19,601 (224)

Sequence alignments between CDR3 sequences and the top hits.

Sequence alignments between CDR3 sequences and the top hits.
Aleksi Sutinen (10039145), Oda C. Krokengen (6812267), Sarah Weber (153709), Andrea J. Lopez (4990781), José M. Godoy Muñoz (18462075), Lasse Neset (18215919), Sigurbjörn Markússon (10803121), Eleni Christakou (11731539), Clive R. Bramham (10181909), Petri Kursula (90066)   +9 more
core   +1 more source

Probing TCR Specificity Using Artificial In Vivo Diversification of CDR3 Regions

European Journal of Immunology
ABSTRACT The T‐cell receptor sequences expressed on cells recognizing a specific peptide in the context of a given MHC molecule can be explored for common features that might explain their antigen specificity. However, despite the development of numerous experimental and bioinformatic strategies, the specificity ...
Giorgetti, O., Haas-Assenbaum, A., Boehm, T. ; https://orcid.org/0000-0001-5172-7478   +2 more
openaire   +4 more sources

Length diversity in CDR3 Domain of Immunoglobulin Kappa Chain during the Human Development

, 1998
The third complementarity determining region (CDR3) of the immunoglobin (Ig) kappa (к) chain is known to be located at the center of antigen binding groove and critical for antibody specificity.
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core  

Schematic diagram of the CDR3 (AA)-relative analysis and in-frame percent (ORF) statistics.

, 2016
a-c The CDR3-related analysis of the NO.1, NO.2, and NO.3 camels including CDR3 length (AA) and proportion; d The comparison of in-frame percent of antibody variable region genes between VH and VHH clones of three camels.
Ruxue Lu (3097914), Naibo Yang (3097908), Mengying He (593736), Wei Zhang (405), Yanrui Ye (3097917), Jian Wang (5901), Zhe Ren (558949), Changxi Wang (658966), Xiaobo Duan (272150), Xiao Liu (65413), Xinyang Li (1543561), Longfei Fu (3097911), Kai Yang (73590), Huanming Yang (5905), Changjiang Zhang (360290), Chao Nie (418889), Jinghua Wu (436901), Wen Tan (102776)   +17 more
core   +1 more source

Landscape of IGH germline genes of Chiroptera and the pattern of Rhinolophus affinis bat IGH CDR3 repertoire

Microbiology Spectrum
The emergence and re-emergence of abundant viruses from bats that impact human and animal health have resulted in a resurgence of interest in bat immunology. Characterizing the immune receptor repertoire is critical to understanding how bats coexist with
Long Ma, Longyu Liu, Jun Li, Hao Zhou, Jiaping Xiao, Qingqing Ma, Xinsheng Yao   +6 more
doaj   +1 more source

Similar usage of T‐cell receptor β‐chain between tumor and adjacent normal tissue in hepatocellular carcinoma

Cancer Medicine
Background In this study, we comprehensively profiled the T‐cell receptor (TCR) repertoire of the tumor and adjacent normal tissue in patients with HBV‐associated hepatocellular carcinoma (HCC) and determined the baseline characteristics and clinical ...
Jie‐Zuan Yang, Shao‐Yan Xu, Dang‐Sheng Xiao, Jin‐You Li, Xiu‐Yuan Jin, Dong Yan   +5 more
doaj   +1 more source

Identification of apolipoprotein B–reactive CDR3 motifs allows tracking of atherosclerosis-related memory CD4+T cells in multiple donors

Frontiers in Immunology
IntroductionAtherosclerosis is a major pathological condition that underlies many cardiovascular diseases (CVDs). Its etiology involves breach of tolerance to self, leading to clonal expansion of autoreactive apolipoprotein B (APOB)–reactive CD4+T cells ...
Payel Roy, Payel Roy, Sujit Silas Armstrong Suthahar, Jeffrey Makings, Klaus Ley, Klaus Ley   +5 more
doaj   +1 more source

Comprehensive characterization and database construction of immune repertoire in the largest Chinese glioma cohort

iScience
Summary: Immune receptor repertoire is valuable for developing immunotherapeutic interventions, but remains poorly understood across glioma subtypes including IDH wild type, IDH mutation without 1p/19q codeletion (IDHmut-noncodel) and IDH mutation with ...
Lu Wang, Zhiyuan Xu, Wei Zhang, Lin Li, Xiao Liu, Jing Zhang   +5 more
doaj   +1 more source

Mechanism of TLR-4 upregulation induced in PM by V_HCDR3.

, 2013
Mechanism of TLR-4 upregulation induced in PM by VHCDR3.
Federica Ortelli (368707), Stefania Conti (92354), Walter Magliani (92353), Eva Pericolini (290617), Anna Vecchiarelli (290625), Elena Gabrielli (290619), Francesco Bistoni (184196), Luciano Polonelli (92344), Elio Cenci (290621), Tecla Ciociola (309997)   +9 more
core   +1 more source

α-chain TCR Transcripts (CDR3 Region) Identified in PBMC from Normal Donors.

, 2019
α-chain TCR Transcripts (CDR3 Region) Identified in PBMC from Normal Donors.
Wan Lu Lin (6984068), Charalambos Solomides (3232506), Ifeyinwa Nwaneshiudu (6984071), John Gaughan (6984074), Xiaoying Zhang (52883), Song Lu (455448), John V. White (375515), Lisa L. Merritt (6984065), Raquel I. Judy (6984062), Dimitri S. Monos (203240), Emilia L. Oleszak (6984077), Chris D. Platsoucas (6984080)   +11 more
core   +1 more source