Results 11 to 20 of about 13,695 (188)

CEBPB promotes transformation of endometrial complex atypical hyperplasia to endometrial cancer [PDF]

BMC Cancer
Background As the precursor malignancy of endometrial cancer (EC), about 50% of endometrial complex atypical hyperplasia (CAH) will eventually progress to EC. Elucidating the underlying transformation mechanisms could aid in disease management.
Jiahong Tan, Lin Zhao, Daoqi Wang, Xiaodie Wu, Yongxiang Bi, Hanying Wang, Na Ma, Dehong Yang, Wei Dong, Jie Zhang   +9 more
doaj   +3 more sources

Mendelian Randomization and Transcriptome Analyses Reveal Important Roles for CEBPB and CX3CR1 in Osteoarthritis [PDF]

Bioengineering
Background: Chemokines play a pivotal role in the progression of osteoarthritis (OA), but their exact mechanisms remain unclear. This study aimed to identify potential chemokine-associated biomarkers and investigate their causal relationships with OA ...
Hui Gao, Xinling Gan, Jing He, Chengqi He   +3 more
doaj   +4 more sources

Inhibition of CEBPB Attenuates Lupus Nephritis via Regulating Pim-1 Signaling

Mediators of Inflammation, 2022
Systemic lupus erythematosus (SLE) is an autoimmune disease leading to inflammatory damage in multiple target organs, and lupus nephritis (LN) is one of the most life-threatening organ manifestations.
Xiaoyang Wang, Weili Cheng, Xiaopan Chen, Yanan Gong, Guangjie Wang, Xiaoxue Zhang, Yuanyuan Qi   +6 more
doaj   +3 more sources

Changes in CEBPB expression in circulating leukocytes following eccentric elbow-flexion exercise [PDF]

The Journal of Physiological Sciences, 2015
This is the final version of the article. Available from Springer via the DOI in this record.In mouse models, CCAAT enhancer-binding protein beta (CEBPB) is necessary for M2 macrophage-mediated regeneration after muscle injury.
Blackwell, James R., Ferrucci, L, Harries, LW, Jones, Andrew M., Melzer, D, Pilling, LC   +5 more
core   +7 more sources

Eukaryotic translation initiation factor 3 subunit B promotes head and neck cancer via CEBPB translation [PDF]

Cancer Cell International, 2022
Highlights EIF3B is a prognostic biomarker for HNSCC risk; EIF3B promotes HNSCC progression in vitro and in vivo; EIF3B promotes CEBPB translation and activates the MAPK pathway; IL6R and CCNG2 are targets of EIF3B-regulated CEBPB translation.
Chengzhi Xu, Yupeng Shen, Yong Shi, Ming Zhang, Liang Zhou   +4 more
doaj   +3 more sources

Integrated bioinformatic identification and translational validation of key biomarkers and therapeutic candidates for preeclampsia-related acute kidney injury [PDF]

Archives of Gynecology and Obstetrics
Objective This study aimed to identify and validate key biomarkers for PE-AKI and to explore potential therapeutic candidates through an integrated bioinformatic and experimental approach.
Lina Gao, Dong Yan, Xiaohui Liu, De Chen, Xiaoling Liu, Jian Liu   +5 more
doaj   +2 more sources

CEBPB promotes ulcerative colitis-associated colorectal cancer by stimulating tumor growth and activating the NF-κB/STAT3 signaling pathway [PDF]

Open Life Sciences
Ulcerative colitis-associated colorectal cancer (UCCRC) represents a significant complication of ulcerative colitis. CEBPB has been shown to promote the invasion of colon cancer cells.
Gao Shan, Wang Wei, Tong Xu-Dong, Wang Dao-Rong, Tian Ai-Xia, Yang Wei, Chen Jin-Min   +6 more
doaj   +2 more sources

Deficiency of RARα Suppresses Decidualization via Downregulating CEBPB Transcription in Women With Recurrent Implantation Failure

Frontiers in Endocrinology, 2022
BackgroundRecurrent implantation failure (RIF) is a disease associated with endometrial receptivity dysfunction. Retinoic acid receptor alpha (RARα) is an important protein in many biological processes, such as differentiation and development.
Caiyi Huang, Caiyi Huang, Caiyi Huang, Caiyi Huang, Caiyi Huang, Qian Zhang, Qian Zhang, Qian Zhang, Tianxiang Ni, Tianxiang Ni, Tianxiang Ni, Tingting Zhou, Tingting Zhou, Tingting Zhou, Chunzi Lv, Chunzi Lv, Chunzi Lv, Yan Li, Yan Li, Yan Li, Junhao Yan, Junhao Yan, Junhao Yan, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen, Zi-Jiang Chen   +27 more
doaj   +3 more sources

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation [PDF]

Advanced Science
Neoadjuvant chemoradiotherapy (nCRT) improves outcomes for locally advanced esophageal squamous cell carcinoma (ESCC) but exhibits variable efficacy due to heterogeneous radiosensitivity.
Zhang Lin, Meilian Yao, Xin Xu, Dong Zhang, Lei Xu, Ling Rong, Xiaohang Wang, Yi Duan, Chengkun Chen, Jun Gu, Yao Zhang, Qiang Liu, Qing Ye, Gaoping Cui, Yujun Hao, Xiumei Ma   +15 more
doaj   +2 more sources

CEBPB-mediated upregulation of SERPINA1 promotes colorectal cancer progression by enhancing STAT3 signaling

Cell Death Discovery
Colorectal cancer (CRC) is a highly malignant carcinoma associated with poor prognosis, and metastasis is one of the most common causes of death in CRC. Serpin Family A Member 1 (SERPINA1) is a serine protease inhibitor from the Serpin family.
Yiming Ma, Ying Chen, Lei Zhan, Qian Dong, Yuanhe Wang, Xiaoyan Li, Lian He, Jingdong Zhang   +7 more
doaj   +3 more sources