Results 71 to 80 of about 10,239 (195)

The distribution of the maximum values of signals in the positive and negative samples for CEBPB, CUX1, TCF, and CTCF.

, 2022
As we can see, the maximum values of signals in the positive and negative samples for CEBPB, CUX1, and TCF are difficult to distinguish while the ones for CTCF are easy to distinguish. (TIF)
Qinhu Zhang (12219347), Ying He (125930), Zhen Cui (2966148), De-Shuang Huang (396909), Zhanheng Chen (12219353), Zhenhao Guo (11724770), Qi Liu (33068), Siguo Wang (12219350)   +7 more
core   +1 more source

Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response

The FEBS Journal, EarlyView.
Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril, Matthieu Le Gallo, Elodie Lafont   +2 more
wiley   +1 more source

Transcription factor CEBPB mediates intracranial aneurysm rupture by inflammatory and immune response

CNS Neuroscience & Therapeutics
Abstract Introduction Genetic factors play a major part in mediating intracranial aneurysm (IA) rupture. However, research on the role of transcription factors (TFs) in IA rupture is rare. Aims Bioinformatics analysis
Zhongbin Tian, Xuefang Wu, Baorui Zhang, Wei Li, Chao Wang   +4 more
openaire   +2 more sources

Additional file 7 of Stress-induced epinephrine promotes epithelial-to-mesenchymal transition and stemness of CRC through the CEBPB/TRIM2/P53 axis

, 2022
Additional file 7: Figure S7.
Yan Shu (441370), Chenxing Jian (12829267), Zhengyi Liu (838941), Wenzheng Yuan (838940), Zili Zhou (4452364), Shengbo Han (8078363), Haijun Bao (12829264), Ning Zhao (84707), Xiaogang Shu (838942)   +8 more
core   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson, Tariq Taylor, Dumitru Constantin‐Teodosiu, Despina Constantin, Martino V. Franchi, Dorothee Auer, Paul L. Greenhaff   +6 more
wiley   +1 more source

MiR-320 inhibits PRRSV replication by targeting PRRSV ORF6 and porcine CEBPB

Veterinary Research
AbstractPorcine reproductive and respiratory syndrome (PRRS), a highly contagious disease caused by Porcine reproductive and respiratory syndrome virus (PRRSV), results in huge economic losses to the world pig industry. MiRNAs have been reported to be involved in regulation of viral infection.
Xiaoxiao Gao, Xiangbin You, Guowei Wang, Mengtian Liu, Longlong Ye, Yufeng Meng, Gan Luo, Dequan Xu, Min Liu   +8 more
openaire   +3 more sources

Transfer of paracetamol across the placenta and fetal blood–brain barriers and its safety for use in pregnancy

The Journal of Physiology, EarlyView.
Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
wiley   +1 more source

Itraconazole inhibits tumor growth via CEBPB‐mediated glycolysis in colorectal cancer

Cancer Science
AbstractAdvanced colorectal cancer (CRC) is characterized by a high recurrence and metastasis rate, which is the primary cause of patient mortality. Unfortunately, effective anti‐cancer drugs for CRC are still lacking in clinical practice. We screened FDA‐approved drugs by utilizing targeted organoid sequencing data and found that the antifungal drug ...
Yong Zhang, Lu Li, Feifei Chu, Huili Wu, Xingguo Xiao, Jianping Ye, Kunkun Li   +6 more
openaire   +2 more sources

C/EBPβ deletion in macrophages impairs mammary gland alveolar budding during the estrous cycle

Life Science Alliance
Macrophage C/EBPβ contributes to alveolar budding during the estrous cycle by providing critical signaling to mammary epithelial cells. Macrophages have important roles in mammary gland development and tissue homeostasis, but the specific mechanisms that
Michelle D Rojo, Ishitri Bandyopadhyay, Caitlin M Burke, Alexa D Sturtz, Emily S Phillips, Megan G Matherne, Samuel J Embrey, Rebecca LaRue, Yinjie Qiu, Kathryn L Schwertfeger, Heather L Machado   +10 more
doaj   +1 more source