Results 101 to 110 of about 9,042,025 (370)

Evolving Therapy for Celiac Disease

Frontiers in Pediatrics, 2019
Gluten is known to be the main triggering factor for celiac disease (CeD), an immune-mediated disorder. CeD is therefore managed using a strict and lifelong gluten-free diet (GFD), the only effective treatment available currently.
Shakira Yoosuf, G. Makharia
semanticscholar   +1 more source

Prognostic factors for patients with esophageal cancer who achieve pathological complete response in the primary tumor after upfront chemotherapy or chemoradiotherapy

Annals of Gastroenterological Surgery, EarlyView.
Male gender and pathological lymph node metastasis are independent poor prognostic factors in patients with esophageal cancer who receive upfront treatment followed by surgery and achieved pathological complete response of the primary tumor. Among patients without pathological lymph node metastasis, the upfront chemotherapy group showed significantly ...
Masaaki Motoori, Koji Tanaka, Hiroshi Miyata, Makoto Yamasaki, Osamu Shiraishi, Atsushi Takeno, Tomoki Makino, Keijiro Sugimura, Takushi Yasuda, Yuichiro Doki   +9 more
wiley   +1 more source

Serum thyroid hormone antibodies are frequent in patients with polyglandular autoimmune syndrome type 3, particularly in those who require thyroxine treatment [PDF]

, 2017
Polyglandular autoimmune syndrome (PAS) type 3 consists of autoimmune thyroid disease (AITD) coexisting with ≥1 non-thyroidal autoimmune disease (NTAID) other than Addison’s disease and hypoparathyroidism. We evaluated the prevalence and repertoire of
Benvenga, Salvatore, Centanni, Marco, Di Bari, Flavia, Galletti, Marina, Mandolfino, Mattia, Santaguida, MARIA GIULIA, Segni, Maria, Virili, Camilla, Vita, Roberto   +8 more
core   +1 more source

Celiac Disease: A Review of Current Concepts in Pathogenesis, Prevention, and Novel Therapies

Frontiers in Pediatrics, 2018
Our understanding of celiac disease and how it develops has evolved significantly over the last half century. Although traditionally viewed as a pediatric illness characterized by malabsorption, it is now better seen as an immune illness with systemic ...
J. Tye-Din, H. Galipeau, D. Agardh
semanticscholar   +1 more source

Clinical role of intraperitoneal chemotherapy in patients with pancreatic ductal adenocarcinoma concomitant with occult peritoneal dissemination: A multicenter retrospective study

Annals of Gastroenterological Surgery, EarlyView.
The effectiveness of intraperitoneal chemotherapy using paclitaxel (i.p.‐PTX) in pancreatic ductal adenocarcinoma (PDAC) patients with peritoneal dissemination remains elusive. This study indicated that the i.p.‐PTX therapy may improve survival in selected patients with PDAC, in particular those with occult peritoneal dissemination.
Tomohisa Yamamoto, Toshio Shimokawa, Masamichi Hayashi, Masamichi Mizuma, Katsuhisa Hirano, Atsushi Oba, Toshimichi Asano, Hideyo Miyato, Makoto Yoshida, Ippei Matsumoto, Yasunari Kawabata, Katsunori Sakamoto, Fuyuhiko Motoi, Shigeto Ishii, Yuki Homma, Hiromitsu Maehira, Yutaro Matsunaga, Tetsuya Ikemoto, Masafumi Nakamura, Yuko Mataki, Tsuyoshi Notake, Keiichi Akahoshi, Hideki Takami, So Yamaki, Daisuke Hashimoto, Yasutoshi Kimura, Satoshi Hirano, Yosuke Inoue, Tsutomu Fujii, Michiaki Unno, Yasuhiro Kodera, Joji Kitayama, Sohei Satoi, the Study Group of Pancreatic Ductal Adenocarcinoma with Peritoneal Dissemination   +33 more
wiley   +1 more source

CheXseen: Unseen Disease Detection for Deep Learning Interpretation of Chest X-rays [PDF]

arXiv, 2021
We systematically evaluate the performance of deep learning models in the presence of diseases not labeled for or present during training. First, we evaluate whether deep learning models trained on a subset of diseases (seen diseases) can detect the presence of any one of a larger set of diseases.
arxiv  

How mucosal epithelia deal with stress: Role of NKG2D/NKG2D ligands during inflammation [PDF]

, 2017
Mucosal epithelia encounter both physicochemical and biological stress during their life and have evolved several mechanisms to deal with them, including regulation of immune cell functions.
Alessandra Soriani, Angela Santoni, Angela Santoni, Cristina Cerboni, Fabrizio Antonangeli, Giuseppe Sciumè   +5 more
core   +2 more sources

A severity‐based tumor‐superior mesenteric/portal vein interface grading criteria as a predictor of survival outcomes in pancreatic head ductal adenocarcinoma patients undergoing pancreaticoduodenectomy following neoadjuvant chemoradiotherapy

Annals of Gastroenterological Surgery, EarlyView.
PDAC patients with the radiological severe interface (≥25 contact length and ≥210 degrees circumferential tumor‐SMV/PV interface) may help predict poor survival outcomes preoperatively. Abstract Aim To assess the ability of a new severity‐based tumor‐superior mesenteric/portal vein interface criteria to predict survival outcomes in pancreatic ductal ...
Benson Kaluba, Naohisa Kuriyama, Motonori Nagata, Takahiro Ito, Aoi Hayasaki, Takehiro Fujii, Yasuhiro Murata, Akihiro Tanemura, Masashi Kishiwada, Shugo Mizuno   +9 more
wiley   +1 more source

Symptoms and biomarkers associated with undiagnosed celiac seropositivity

BMC Gastroenterology, 2021
Background Studies have indicated that underdiagnosis and diagnostic delay are common in celiac disease. Therefore, it is important to increase our knowledge of what symptoms and biomarkers could identify undiagnosed cases of celiac disease.
Line Lund Kårhus, Janne Petersen, Katja Biering Leth-Møller, Line Tang Møllehave, Anja Lykke Madsen, Betina Heinsbæk Thuesen, Peter Schwarz, Jüri J. Rumessen, Allan Linneberg   +8 more
doaj   +1 more source

Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease.

Gastroenterology, 2019
BACKGROUND & AIMS Development of celiac disease is believed to involve the transglutaminase-dependent response of CD4+ T cells toward deamidated gluten peptides in the intestinal mucosa of individuals with specific HLA-DQ haplotypes.
L. S. Høydahl, Lisa Richter, Rahel Frick, O. Snir, Kristin S. Gunnarsen, O. J. Landsverk, Rasmus Iversen, J. Jeliazkov, Jeffrey J. Gray, E. Bergseng, Stian Foss, Shuo-Wang Qiao, K. Lundin, J. Jahnsen, F. Jahnsen, I. Sandlie, L. Sollid, G. Løset   +17 more
semanticscholar   +1 more source