Results 61 to 70 of about 9,235,327 (330)

Fecal calprotectin in healthy children aged 4–16 years

Scientific Reports, 2020
Reference values of fecal calprotectin (fCP) have not been convincingly established in children. We aimed to investigate fCP concentrations in a larger population of healthy children aged 4–16 years to analyze more in depth the behavior of fCP in this ...
María Roca, Ana Rodriguez Varela, Eva Carvajal, Ester Donat, Francisco Cano, Ana Armisen, Maria Jose Vaya, Helena Ekoff, David Hervas, Niclas Rydell, Carmen Ribes-Koninckx   +10 more
doaj   +1 more source

The Gut Microbiota in Celiac Disease and Probiotics

Nutrients, 2019
Celiac disease (CeD) is an immune-mediated enteropathy, and unique in that the specific trigger is known: gluten. The current mainstay of therapy is a gluten-free diet (GFD). As novel therapies are being developed, complementary strategies are also being
R. Chibbar, L. Dieleman
semanticscholar   +1 more source

Celiac Disease Prevention [PDF]

Frontiers in Pediatrics, 2018
Celiac disease (CD) is a common autoimmune disorder induced by ingestion of gluten in genetically susceptible individuals. Despite the prerequisite for a genetic predisposition, only a minority of the 40% of the Caucasian population that has this genetic predisposition develops the disease.
Meijer, C., Shamir, R., Szajewska, H., Mearin, L.   +3 more
openaire   +5 more sources

Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice

Advanced Science, EarlyView.
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia, Xiaoyuan Jing, Ruoxi Wang, Mengke Su, Pei Wang, Yingxin Feng, Xiaohu Ren, Longfang Tu, Ping Wei, Zhen Lu, Yicong Jia, Feng Hong, Zhizhun Mo, Jiemeng Zou, Kang Huang, Caiyun Yan, Qianhui Zou, Liang Wang, Guoping Zhong, Zhi Zeng, Qiuliyang Yu, Wen Su, Xifei Yang, Fan Pan, Jianzhi Wang, Liping Wang, Lijun Kang, Paul J. Kenny, Zuxin Chen, Xin‐an Liu   +29 more
wiley   +1 more source

Comparison of several author indices for gauging academic productivity

Informatics in Medicine Unlocked, 2019
Background: Many author indices exist to gauge academic productivity. Several of these indices are calculated based upon an author's scholarly publication record, but the measurement methodology to calculate each index varies considerably, and the ...
Edward J. Ciaccio, Govind Bhagat, Benjamin Lebwohl, Suzanne K. Lewis, Carolina Ciacci, Peter H. Green   +5 more
doaj   +1 more source

Association of Gluten Intake During the First 5 Years of Life With Incidence of Celiac Disease Autoimmunity and Celiac Disease Among Children at Increased Risk.

Journal of the American Medical Association (JAMA), 2019
Importance High gluten intake during childhood may confer risk of celiac disease. Objectives To investigate if the amount of gluten intake is associated with celiac disease autoimmunity and celiac disease in genetically at-risk children.
Carin Andrén Aronsson, Hye-Seung Lee, Elin M. Hård af Segerstad, U. Uusitalo, Jimin Yang, S. Koletzko, E. Liu, K. Kurppa, P. Bingley, J. Toppari, A. Ziegler, J. She, W. Hagopian, M. Rewers, B. Akolkar, J. Krischer, S. Virtanen, J. Norris, D. Agardh   +18 more
semanticscholar   +1 more source

Long‐Term Survival of Two Versus Three Courses of Preoperative Cisplatin and Fluorouracil Plus Docetaxel for Locally Advanced Esophageal Cancer: A Multicenter Randomized Phase II Trial

Annals of Gastroenterological Surgery, EarlyView.
This multi‐institutional, randomized, phase II trial aimed to investigate the long‐term survival outcomes of two versus three courses of DCF for locally advanced esophageal squamous cell carcinoma (ESCC). The 5‐year overall survival and progression‐free survival rates for the three and two course groups were 70.7% vs. 63.8% (hazard ratio (HR) = 0.91, p 
Takahito Sugase, Hiroshi Miyata, Takashi Kanemura, Norihiro Matsuura, Tomoki Makino, Makoto Yamasaki, Koji Tanaka, Kotaro Yamashita, Kota Momose, Osamu Shiraishi, Keijiro Sugimura, Masaaki Motoori, Kazumasa Fujitani, Atsushi Takeno, Motohiro Hirao, Yutaka Kimura, Taroh Satoh, Masahiko Yano, Yuichiro Doki, Takushi Yasuda   +19 more
wiley   +1 more source

Dissecting the contribution of single nucleotide polymorphisms in CCR9 and CCL25 genomic regions to the celiac disease phenotype

Journal of Translational Autoimmunity, 2021
Purpose and objectives: Given their role in homing immune cells to the intestine, CC motif chemokine receptor 9 (CCR9) and its specific ligand CC motif chemokine ligand 25 (CCL25) are interesting candidate genes for celiac disease.
Laura Airaksinen, Juliana XM. Cerqueira, Heini Huhtala, Päivi Saavalainen, Dawit A. Yohannes, Markku Mäki, Kalle Kurppa, Elina Kilpeläinen, Anastasia Shcherban, Aarno Palotie, Katri Kaukinen, Katri Lindfors   +11 more
doaj   +1 more source

Human gut derived-organoids provide model to study gluten response and effects of microbiota-derived molecules in celiac disease

Scientific Reports, 2019
Celiac disease (CD) is an immune-mediated disorder triggered by gluten exposure. The contribution of the adaptive immune response to CD pathogenesis has been extensively studied, but the absence of valid experimental models has hampered our understanding
Rachel Freire, L. Ingano, G. Serena, Murat Çetinbas, A. Anselmo, A. Sapone, R. Sadreyev, A. Fasano, Stefania Senger   +8 more
semanticscholar   +1 more source

External Validation of an Automated Surgical Step Recognition Model for Robotic Distal Gastrectomy (RDG) Using a Multicenter Dataset

Annals of Gastroenterological Surgery, EarlyView.
Our present study reveals that surgical step recognition performs moderately well when trained on video data from a single institution and applied to an external institution's data. Nevertheless, our model substantially improves its prediction capabilities when trained on the same amount of data from multiple institutions.
James S. Strong, Masahiro Yura, Masashi Takeuchi, Hirofumi Kawakubo, Tasuku Furube, Yusuke Maeda, Satoru Matsuda, Takahiro Kinoshita, Yuko Kitagawa   +8 more
wiley   +1 more source