Results 71 to 80 of about 9,147,247 (396)
Emerging patterns of genetic overlap across autoimmune disorders. [PDF]
, 2012 Most of the recently identified autoimmunity loci are shared among multiple autoimmune diseases. The pattern of genetic association with autoimmune phenotypes varies, suggesting that certain subgroups of autoimmune diseases are likely to share ...
Criswell, Lindsey A +1 more
core +1 more source
Small RNA Toxin‐Assisted Evolution of GC‐Preferred ErCas12a for Enhanced Genome Targeting Range
Advanced Science, EarlyView.ErCas12a is engineered to target GC‐rich PAMs using a small RNA toxin‐aided positive screening system. The resulting variant, enErCas12a, exhibits an expanded PAM profile and facilitates efficient gene editing in both bacterial and mammalian cells, while preserving high targeting specificity for both canonical and non‐canonical PAM targets.
Zehua Chen +8 more
wiley +1 more source
Advanced Science, 2023 Dermatitis herpetiformis (DH) is an inflammatory skin disorder often considered as an extra intestinal manifestation of celiac disease (CeD).
Saykat Das +11 more
doaj +1 more source
Effects of Celiac Disease on Religion and Language [PDF]
, 2016 Celiac disease is an autoimmune disease that prevents people from digesting gluten. The diagnosis of Celiac impacts more than physical health, it irrevocably alters a person’s conception of self. Ordinary activities like airport travel, staying in hotels,
Gustafson, Solveig L. +1 more
core +1 more source
A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease [PDF]
, 2011 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Annese, V +17 more
core +8 more sources
Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance
Advanced Science, EarlyView.Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai +5 more
wiley +1 more source
Fecal calprotectin in healthy children aged 4–16 years
Scientific Reports, 2020 Reference values of fecal calprotectin (fCP) have not been convincingly established in children. We aimed to investigate fCP concentrations in a larger population of healthy children aged 4–16 years to analyze more in depth the behavior of fCP in this ...
María Roca +10 more
doaj +1 more source
Immune response to vaccines in children with celiac disease [PDF]
, 2017 Celiac disease (CD) is an immune-mediated systemic condition evoked by ingestion of gluten and related prolamines in genetically susceptible subjects. The disease is featured by a variable combination of clinical signs, specific antibodies, HLA-DQ2 and ...
ANANIA, Caterina +4 more
core +1 more source
The Gut Microbiota in Celiac Disease and Probiotics
Nutrients, 2019 Celiac disease (CeD) is an immune-mediated enteropathy, and unique in that the specific trigger is known: gluten. The current mainstay of therapy is a gluten-free diet (GFD). As novel therapies are being developed, complementary strategies are also being
R. Chibbar, L. Dieleman
semanticscholar +1 more source
Advanced Science, EarlyView.A healthcare toilet system is introduced to passively measure defecation behavior. Real‐time data on stool dropping duration, thickness, and a newly defined “eu‐tenesmus” interval show correlations with stool form and gender differences. Results from 45 defecation events reveal a promising method for comprehensive defecation analysis.
Zhiquan Song +16 more
wiley +1 more source