Results 11 to 20 of about 4,481,323 (329)

Direct and Indirect Antioxidant Effects of Selected Plant Phenolics in Cell-Based Assays. [PDF]

Molecules, 2021
Background: Oxidative stress is a key factor in the pathophysiology of many diseases. This study aimed to verify the antioxidant activity of selected plant phenolics in cell-based assays and determine their direct or indirect effects.
Treml J, Večeřová P, Herczogová P, Šmejkal K.   +3 more
europepmc   +2 more sources

A multicenter comparison of MOG-IgG cell-based assays. [PDF]

Neurology, 2019
Objectives To compares 3 different myelin oligodendrocyte glycoprotein–immunoglobulin G (IgG) cell-based assays (CBAs) from 3 international centers.
Waters PJ, Komorowski L, Woodhall M, Lederer S, Majed M, Fryer J, Mills J, Flanagan EP, Irani SR, Kunchok AC, McKeon A, Pittock SJ.   +11 more
europepmc   +2 more sources

Cytometric cell-based assays for anti-striational antibodies in myasthenia gravis with myositis and/or myocarditis. [PDF]

Sci Rep, 2019
The purposes of the present study were to identify anti-striational antibodies in myasthenia gravis (MG) patients with myositis and/or myocarditis using a combination of cell-based assays and flow cytometry (cytometric cell-based assays) and to describe ...
Kufukihara K, Watanabe Y, Inagaki T, Takamatsu K, Nakane S, Nakahara J, Ando Y, Suzuki S.   +7 more
europepmc   +2 more sources

Cross-linked electrospun gelatin nanofibers for cell-based assays. [PDF]

Annu Int Conf IEEE Eng Med Biol Soc, 2018
The present study evaluates the crosslinking of electrospun gelatin nanofibers by physical and chemical methods to further elucidate the importance of the application of gelatin scaffold platforms for cell-based assays.
Ghassemi Z, Slaughter G.
europepmc   +2 more sources

3D Cell-Based Assays for Drug Screens: Challenges in Imaging, Image Analysis, and High-Content Analysis

SLAS discovery : advancing life sciences R & D, 2019
The introduction of more relevant cell models in early preclinical drug discovery, combined with high-content imaging and automated analysis, is expected to increase the quality of compounds progressing to preclinical stages in the drug development ...
T. Booij, L. Price, E. Danen
semanticscholar   +1 more source

Cordycepin attenuates migration and invasion of HSC-4 oral squamous carcinoma cells through autophagy-dependent FAK/Akt and MMP2/MMP9 suppression

Journal of Dental Sciences, 2022
Background/purpose: Cordycepin has been proposed anti-cancer effects, however, it is unclear whether and how cordycepin affects oral squamous carcinoma cell (OSCC) migration and invasion.
Thunwa Binlateh, Nawapol Uppatcha, Jutamast Thepchai, Yanaphat Pleungtuk, Parinya Noisa, Pilaiwanwadee Hutamekalin, Paiboon Jitprasertwong   +6 more
doaj  

The antioxidant activity and active sites of delphinidin and petunidin measured by DFT, in vitro chemical-based and cell-based assays.

Journal of food biochemistry, 2019
A computational DFT B3LYP method with 6-311G (d,p) basis set, the in vitro chemical-based and cellular antioxidant activity (CAA) assays were applied in this study to explain the structure-antioxidant activity relationships of delphinidin and petunidin ...
Bangjing Chen, Yun Ma, Hongyan Li, Xuan Chen, Chengyue Zhang, Hongming Wang, Z. Deng   +6 more
semanticscholar   +1 more source

Protocol for altering connexin hemichannel function in primary chicken lens fiber cells using high-titer retroviral RCAS(A) infection

STAR Protocols, 2023
Summary: Connexins (Cxs) play a crucial role in maintaining lens transparency. Here, we present a protocol for altering Cx hemichannel (HC) function in primary chicken lens fiber cells using high-titer retroviral replication competent avian sarcoma ...
Yu Du, Francisca M. Acosta, Jianping Zhang, Yuxin Tong, Yumeng Quan, Sumin Gu, Jean X. Jiang   +6 more
doaj  

Identification and Characterization of Inhibitors of a Neutral Amino Acid Transporter, SLC6A19, Using Two Functional Cell-Based Assays

SLAS discovery : advancing life sciences R & D, 2019
SLC6A19 (B0AT1) is a neutral amino acid transporter, the loss of function of which results in Hartnup disease. SLC6A19 is also believed to have an important role in amino acid homeostasis, diabetes, and weight control. A small-molecule inhibitor of human
S. Danthi, B. Liang, Oanh Smicker, B. Coupland, J. Gregory, Estelle Gefteas, D. Tietz, Helen Klodnitsky, Kristen L. Randall, A. Belanger, Theresa A. Kuntzweiler   +10 more
semanticscholar   +1 more source

Ex vivo assay to evaluate the efficacy of drugs targeting sphingolipids in preventing SARS-CoV-2 infection of nasal epithelial cells

STAR Protocols, 2021
Summary: This protocol enables the testing of drugs against infection of epithelial cells with SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2), using pseudo-typed replication deficient vesicular stomatitis virus particles (pp-VSV) presenting
Katrin Anne Becker, Alexander Carpinteiro, Markus Hoffmann, Stefan Pöhlmann, Johannes Kornhuber, Erich Gulbins   +5 more
doaj