Results 51 to 60 of about 4,735,099 (379)
Cell wall composition and biofilm formation of azoles-susceptible and -resistant Candida glabrata strains [PDF]
, 2011 In the present study, three strains of Candida glabrata have been investigated to shed light on the mechanisms involved in azole resistance during adherence and biofilm formation.
Vitali, Alberto +6 more
core +5 more sources
Microfluidics for cell-based assays
Materials Today, 2005 Microfluidic systems are powerful tools in chemistry, physics, and biology. The behavior of confined fluids differs from macroscopic systems and allows precise control of the chemical composition of fluids, as well as the temporal and spatial patterns of microscopic fluid elements.
Pihl, Johan +3 more
openaire +1 more source
Cross-linked electrospun gelatin nanofibers for cell-based assays
Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2018 The present study evaluates the crosslinking of electrospun gelatin nanofibers by physical and chemical methods to further elucidate the importance of the application of gelatin scaffold platforms for cell-based assays.
Z. Ghassemi, G. Slaughter
semanticscholar +1 more source
Scientific ReportsThe three-dimensional (3D) cell culture system is being employed more frequently to investigate cell engineering and tissue repair due to its close mimicry of in vivo microenvironments.
Amorn Pangjantuk +4 more
doaj +1 more source
Adverse outcome pathway-based analysis of liver steatosis in vitro using human liver cell lines
STAR Protocols, 2023 Summary: Here, we present an in vitro test battery to analyze chemicals for their potential to induce liver triglyceride accumulation, a hallmark of liver steatosis.
Mawien Karaca +8 more
doaj +1 more source
Rational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT. [PDF]
, 2018 FMS-like Tyrosine Kinase 3 (FLT3) is a clinically validated target for acute myeloid leukemia (AML). Inhibitors targeting FLT3 have been evaluated in clinical studies and have exhibited potential to treat FLT3-driven AML.
Bharate, Jaideep B +8 more
core +2 more sources
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes. [PDF]
, 2020 Anti-CRISPRs (Acrs) are small proteins that inhibit the RNA-guided DNA targeting activity of CRISPR-Cas enzymes. Encoded by bacteriophage and phage-derived bacterial genes, Acrs prevent CRISPR-mediated inhibition of phage infection and can also block ...
Doudna, Jennifer A +5 more
core +3 more sources
Engineered basement membranes: from in vivo considerations to cell-based assays.
Integrative Biology, 2018 Improvements in the physiological relevance of cell-based assays have been enabled by the development of various interdisciplinary methods. However, due to their complexity, in vivo structures such as basement membranes (BMs), which regulate the ...
Guillaume Perry +4 more
semanticscholar +1 more source
Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis +9 more
wiley +1 more source