Results 1 to 10 of about 2,835,817 (168)

Cell-free riboswitches

open access: yesRSC Chemical Biology, 2021
Synthetic riboswitches can be used as chemical gene switches in cell-free protein synthesis systems. We provide a current perspective on the state of cell-free riboswitch technologies and their future directions.
Takeshi Tabuchi, Yohei Yokobayashi
openaire   +3 more sources

The necessity of bilateral staging bone marrow examinations for paediatric solid tumours

open access: yesSouth African Journal of Oncology, 2022
Background: Bone marrow aspirates and trephine biopsies (BMATs) form an important part of staging to detect bone marrow metastases of both haematological and nonhaematological neoplasms.
Anne-Cecilia van Marle   +8 more
doaj   +1 more source

Applying Synthetic Biology with Rational Design to Nature’s Greatest Challenges: Bioengineering Immunotherapeutics for the Treatment of Glioblastoma

open access: yesImmuno, 2021
Improvements in bioengineering methodology and tools have allowed for significant progress in the development of therapeutics and diagnostics in medicine, as well as progress in many other diverse industries, such as materials manufacturing, food and ...
Leila A. Mashouf   +4 more
doaj   +1 more source

Cell-free Biosynthesis of Peptidomimetics

open access: yesBiotechnology and Bioprocess Engineering, 2023
A wide variety of peptidomimetics (peptide analogs) possessing innovative biological functions have been brought forth as therapeutic candidates through cell-free protein synthesis (CFPS) systems. A key feature of these peptidomimetic drugs is the use of non-canonical amino acid building blocks with diverse biochemical properties that expand functional
Lee, Kanghun   +5 more
openaire   +3 more sources

A proximity biotinylation-based approach to identify protein-E3 ligase interactions induced by PROTACs and molecular glues

open access: yesNature Communications, 2022
PROTACs and molecular glues target E3 ubiquitin ligases to substrate proteins. Here, the authors develop a proximity biotinylation-based method to identify drug-induced E3 ligase-substrate interactions, enabling the assessment of the target spectrum of ...
Satoshi Yamanaka   +8 more
doaj   +1 more source

Build-a-Cell: Engineering a Synthetic Cell Community

open access: yesLife, 2021
Build-a-Cell is a global network of researchers that aims to develop synthetic living cells within the next decade. These cells will revolutionize the biotechnology industry by providing scientists and engineers with a more complete understanding of ...
Caroline Frischmon   +3 more
doaj   +1 more source

Cell-Free DNA in the Investigation of Miscarriage [PDF]

open access: yesJournal of Clinical Medicine, 2020
Approximately one in four pregnancies result in pregnancy loss, and ~50% of these miscarriages are caused by chromosomal abnormalities. Genetic investigations are recommended after three consecutive miscarriages on products of conception (POC) tissue. Cell-free DNA (cfDNA) has been utilised for prenatal screening, but very little work has been carried ...
Emily Colley   +8 more
openaire   +3 more sources

Blockchain-Based Lightweight Multifactor Authentication for Cell-Free in Ultra-Dense 6G-Based (6-CMAS) Cellular Network

open access: yesIEEE Access, 2023
Cell-Free mMIMO is a part of technology that will be integrated with future 6G ultra-dense cellular networks to ensure unlimited wireless connectivity and ubiquitous latency-sensitive services.
Adnan Shahid Khan   +7 more
doaj   +1 more source

Low-Complexity Beamforming Design for a Cooperative Reconfigurable Intelligent Surface-Aided Cell-Free Network

open access: yesSensors, 2023
Cell-free (CF) networks are proposed to suppress the interference among collocated cells by deploying several BSs without cell boundaries. Nevertheless, as installing several base stations (BSs) may require high power consumption, cooperative CF networks
Muhammad Zain Siddiqi   +6 more
doaj   +1 more source

Preparation of Cell-free Tryptophanase [PDF]

open access: yesNature, 1947
IN our earliest studies on the tryptophanase complex1 active non-viable suspensions of E. coli were used. These had been sterilized by shaking with chloroform, 1 volume to 2 volumes of suspension. The mixture was shaken vigorously to 200 r.p.m. for 4 hours.
E A, DAWES, J, DAWSON, F C, HAPPOLD
openaire   +2 more sources

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