Results 71 to 80 of about 2,118,837 (302)

Cell-free DNA in non-small cell lung cancer

open access: yesActa Medica Lituanica, 2017
Lung cancer is the leading cause of cancer-associated deaths worldwide. Surgery is the standard treatment for early-stage non-small cell lung cancer (NSCLC).
Vaida Gedvilaitė   +2 more
doaj   +1 more source

Another chromosomal assignment for a simian virus 40 integration site in human cells [PDF]

open access: yes, 1978
Somatic cell hybrids derived from fusion of GM637, a human cell line transformed by simian virus 40, and mouse B82 cells were examined for simian virus 40 T antigen, V antigen, and viral DNA.
Kucherlapati, R.   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Advances, Challenges, and Clinical Applications of Donor-derived Cell-free Deoxyribonucleic Acid in Transplantation

open access: yesIndian Journal of Transplantation
Donor-derived cell-free deoxyribonucleic acid (dd-cfDNA) is a promising noninvasive biomarker for monitoring organ transplant rejection and graft status as it is released into the recipient’s bloodstream due to graft injury, ischemia, or immune response.
Vikash Chandra Mishra   +2 more
doaj   +1 more source

Cell-Free DNA in Emergency Medical Care

open access: yesНеотложная медицинская помощь, 2020
. Defining molecules with high prognostic value for predicting the course and outcomes of life-threatening sepsis, severe injuries, vascular accidents remains an urgent problem in emergency medicine. One of the promising candidate biomarkers of emergency
A. D. Filev, V. M. Pisarev
doaj   +1 more source

Recombinant DNA Molecules of Bacteriophage phi X174 [PDF]

open access: yes, 1975
phi X174 DNA structures containing two different parental genomes were detected genetically and examined by electron microscopy. These structures consisted of two monomeric double-stranded DNA molecules linked in a figure 8 configuration.
Benbow, Robert M.   +2 more
core  

Performance of screening for aneuploidies by cell-free DNA analysis of maternal blood in twin pregnancies [PDF]

open access: yes, 2015
Objectives To report clinical implementation of cell‐free DNA (cfDNA) analysis of maternal blood in screening for trisomies 21, 18 and 13 in twin pregnancies and examine variables that could influence the failure rate of the test.
BEVILACQUA, ELISA   +7 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Total cell-free DNA, carcinoembryonic antigen, and C-reactive protein for assessment of prognosis in patients with metastatic colorectal cancer

open access: yesTumor Biology, 2018
In late-stage metastatic colorectal cancer, difficult treatment decisions should incorporate a thorough evaluation of the patient’s general condition and subject for shared decision making.
Karen-Lise Garm Spindler   +8 more
doaj   +1 more source

Changes in the nuclear distribution of DNA polymerase alpha and PCNA/cyclin during the progress of the cell cycle, in a cell-free extract of Xenopus eggs [PDF]

open access: yes, 1989
The nuclear distribution of DNA polymerase alpha and PCNA/cyclin in embryonic nuclei has been investigated, in a cell-free extract of Xenopus eggs that recapitulates a basic cell-cycle in vitro, by indirect immunofluorescence microscopy.
Hutchison, C, Kill, IR
core  

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