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, 2020 The deficits of mammography and the potential of noninvasive diagnostic testing using circulating miRNA profiles are presented in our first review article. Exosomes are important in the transfer of genetic information.
Nagy, Bálint
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Nanogels designed for cell-free nucleic acid sequestration
Nanoscale, 2023A cationic nanogel was designed for scavenging cell-free deoxyribonucleic acid (cfDNA) from chronic wound exudate.
Yuhang Huang +5 more
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Cell-free nucleic acids as biomarkers in dialyzed patients
Journal of Nephrology, 2013In this review, we discuss the origin, possible biological meaning, quantitative and qualitative changes in the concentrations of cell-free nucleic acids in human circulation with regard to renal failure and the process of dialysis. We focus on the inflammatory response and apoptosis known to be in close relationship not only with hemodialysis but also
Marie, Korabecna +4 more
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Label‐Free Live‐Cell Imaging of Nucleic Acids Using Stimulated Raman Scattering Microscopy [PDF]
ChemPhysChem, 2012 Imaging of nucleic acids is important for studying cellular processes such as cell division and apoptosis. A noninvasive label-free technique is attractive.
Xu Zhang +2 more
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Diagnostic developments involving cell-free (circulating) nucleic acids
Clinica Chimica Acta, 2006The detection of circulating nucleic acids has long been explored for the non-invasive diagnosis of a variety of clinical conditions. In earlier studies, detection of circulating DNA has been investigated for the detection of various forms of cancer. Metastasis and recurrence in certain cancer types have been associated with the presence of high levels
Yu-Kwan, Tong, Y M Dennis, Lo
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Cell-free Nucleic Acids as a Non-Invasive Route for Investigating Atherosclerosis
Current Pharmaceutical Design, 2014Metabolic syndrome is directly linked with atherosclerotic burden and cell-free nucleic acids (cf-NA) analysis has recently emerged as a novel research tool in atherosclerosis practice and research. cf-NA are nucleic acids (DNA, mRNA, miRNA, mitochondrial DNA) found in plasma and cell-free fractions of various other biological fluids. They have all the
Darko, Cerne, Jana Lukac, Bajalo
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Circulating Cell-Free Nucleic Acids: Promising Biomarkers of Hepatocellular Carcinoma
Seminars in Oncology, 2012Hepatocellular carcinoma (HCC) is considered to be a fatal disease because of its late diagnosis, underlying liver disease, and refractoriness to systemic treatments. Biomarkers with high sensitivity and specificity that are minimally invasive, reproducible, and easily available have important clinical utility for early diagnosis, prognostication, and ...
Jian, Zhou, Ying-Hong, Shi, Jia, Fan
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Circulating Tumor Cells and Cell-free Nucleic Acids as Biomarkers in Colorectal Cancer
Current Pharmaceutical Design, 2023Abstract: Colorectal cancer (CRC) is currently the second most prevalent cancer diagnosed in women and the third most common kind of cancer in men. Despite tremendous efforts and advancements in diagnostic approaches and treatment options, the mortality rate of CRC accounts for around one million each year globally.
Ghazaleh, Pourali +9 more
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Cell free nucleic acids as diagnostic and prognostic marker in leukemia
memo - Magazine of European Medical Oncology, 2017Nucleic acids in circulation, called cell free DNA (cfDNA) and cell free RNA (cfRNA), have recently been analyzed as suitable diagnostic and prognostic markers in cancer. There have also been several reports about the role of this type of marker in leukemia.
Maryam Eini +3 more
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Genomic Approaches to the Analysis of Cell Free Nucleic Acids
2014Recent advances in high throughput DNA sequencing and microarray technologies have revolutionized the field of genomics and also opened up many opportunities for the analysis of cell-free nucleic acids. These genomic approaches have not only provided a more comprehensive portrait of the landscape of cell-free nucleic acids, but also enabled a number of
Wenying Pan, Stephen R. Quake
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