Results 11 to 20 of about 371,071 (337)

Cell-Penetrating Peptide–Bismuth Bicycles

open access: yesAngewandte Chemie, 2023
Cell-penetrating peptides (CPPs) play a significant role in the delivery of cargos into human cells for a wide range of therapeutic and diagnostic applications. We disclose the first CPPs based on peptide–bismuth bicycles, which can be readily obtained from commercially available peptide precursors, making them highly accessible for a wide range of ...
Saan Voss   +8 more
openaire   +3 more sources

Cell Penetrating Peptides [PDF]

open access: yes, 2022
Classes of Cell-Penetrating Peptides. Mechanisms of Cell Penetration, Interactions of Cell-Penetrating Peptides with Plasma Membranes and Lipid Models. Applications of Cell-Penetrating Peptides.
  +6 more sources

Selective Moonlighting Cell-Penetrating Peptides [PDF]

open access: yesPharmaceutics, 2021
Cell penetrating peptides (CPPs) are molecules capable of passing through biological membranes. This capacity has been used to deliver impermeable molecules into cells, such as drugs and DNA probes, among others. However, the internalization of these peptides lacks specificity: CPPs internalize indistinctly on different cell types. Two major approaches
Rafael Morán-Torres   +5 more
openaire   +3 more sources

Glycosylated Cell‐Penetrating Peptides (GCPPs) [PDF]

open access: yesChemBioChem, 2019
AbstractThe cell membrane regulates the exchange of molecules and information with the external environment. However, this control barrier hinders the delivery of exogenous bioactive molecules that can be applied to correct cellular malfunctions. Therefore, the traffic of macromolecules across the cell membrane represents a great challenge for the ...
Iván Gallego   +8 more
openaire   +4 more sources

Arginine‐rich cell‐penetrating peptides [PDF]

open access: yesFEBS Letters, 2009
Arginine‐rich cell‐penetrating peptides are short cationic peptides capable of traversing the plasma membranes of eukaryotic cells. While successful intracellular delivery of many biologically active macromolecules has been accomplished using these peptides, their mechanisms of cell entry are still under investigation. Recent dialogue has centered on a
Schmidt, Nathan   +3 more
openaire   +2 more sources

Matrix metalloprotein-triggered, cell penetrating peptide-modified star-shaped nanoparticles for tumor targeting and cancer therapy

open access: yesJournal of Nanobiotechnology, 2020
Background Specific targeting ability and good cell penetration are two critical requirements of tumor-targeted delivery systems. In the present work, we developed a novel matrix metalloprotein-triggered, cell-penetrating, peptide-modified, star-shaped ...
F. Guo   +10 more
semanticscholar   +1 more source

Cell-Penetrating Peptides and Transportan [PDF]

open access: yesPharmaceutics, 2021
In the most recent 25–30 years, multiple novel mechanisms and applications of cell-penetrating peptides (CPP) have been demonstrated, leading to novel drug delivery systems. In this review, I present a brief introduction to the CPP area with selected recent achievements.
openaire   +3 more sources

Cell-penetrating Peptides [PDF]

open access: yesJournal of Biological Chemistry, 2003
The present invention discloses cell penetrating peptides and conjugates of a cell penetrating peptide and a cargo molecule.
Jean Philippe Richard   +7 more
openaire   +1 more source

Recent Advances in Cell Penetrating Peptide-Based Anticancer Therapies

open access: yesMolecules, 2019
Cell-penetrating-peptides (CPPs) are small amino-acid sequences characterized by their ability to cross cellular membranes. They can transport various bioactive cargos inside cells including nucleic acids, large proteins, and other chemical compounds ...
Justine Habault, J. Poyet
semanticscholar   +1 more source

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