Results 31 to 40 of about 1,820,621 (315)

Building momentum for adoption of UP-state policy on lines of WHO FCTC Article 5.3

Tobacco Induced Diseases, 2018
Background and challenges to implementation Since India ratified the WHO FCTC, it is obligated to follow WHO FCTC Article 5.3 as well. Indian court too has recognized obligations of India to not violate Article 5.3 of FCTC for instance.
Rahul Kumar Dwivedi, Bobby Ramakant, Satish Tripathi, Shobha Shukla, Dr Rama Kant   +4 more
doaj   +1 more source

Microvesicles as vehicles for tissue regeneration: Changing of the guards [PDF]

, 2016
Purpose of Review: Microvesicles (MVs) have been recognised as mediators of stem cell function, enabling and guiding their regenerative effects. Recent Findings: MVs constitute one unique size class of extracellular vesicles (EVs) directly shed from ...
Davies, R. Wayne, Panagiotou, Nikolaos, Selman, Colin, Shiels, Paul G.   +3 more
core   +1 more source

Modeling the Heart as a Communication System [PDF]

, 2014
Electrical communication between cardiomyocytes can be perturbed during arrhythmia, but these perturbations are not captured by conventional electrocardiographic metrics.
Aguilar-Rodríguez, José, Ashikaga, Hiroshi, Garland, Joshua, Gorsky, Shai, Lusczek, Elizabeth, Marquitti, Flávia Maria Darcie, Thompson, Brian, Wu, Degang   +7 more
core   +2 more sources

The Role of Exosomes in Pancreatic Cancer From Bench to Clinical Application: An Updated Review

Frontiers in Oncology, 2021
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most dismal gastrointestinal malignancies with an overall 5-year survival rate of 8%–9%. The intra-tumor heterogeneity and special tumor microenvironment in PDAC make it challenging to develop ...
Kai Chen, Qi Wang, Marko Kornmann, Xiaodong Tian, Yinmo Yang   +4 more
doaj   +1 more source

An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly [PDF]

, 2010
Erythropoetin-producing hepatoma (Eph) receptors are cell-surface protein tyrosine kinases mediating cell-cell communication. Upon activation, they form signaling clusters.
A Radu Aricescu, AG Leslie, AJ McCoy, AR Aricescu, BC Cunningham, C Litterst, CD Thanos, CJ Vearing, CN Chin, D Nikolov, DP Zelinski, E Yvonne Jones, EB Pasquale, EB Pasquale, Elena Seiradake, Eph Nomenclature Committee, EV Bocharov, F Grueninger-Leitch, FM Smith, G Shaw, Geoff Sutton, H Miao, IW Davis, J Egea, J Wykosky, JD Bendtsen, JE Chrencik, JP Himanen, JP Himanen, JP Himanen, JP Himanen, JP Himanen, K Diedrichs, K Miura, Karl Harlos, KT Lin, M Landau, MA Cooper, MS Kinch, N Carter, ND Zantek, NW Gale, P Emsley, P Gouet, PD Adams, PJ Reeves, RA Lindberg, RF Carvalho, S Davis, S Orsulic, SH Wimmer-Kleikamp, T Nagai, TA Bowden, TS Walter, TS Walter, VT Chang, W Kabsch, YG Lin   +57 more
core   +1 more source

Characterization of Somatic Embryogenesis Receptor-Like Kinase 4 as a Negative Regulator of Leaf Senescence in Arabidopsis

Cells, 2019
Leaf senescence is a genetically controlled process that involves the perception of extracellular signals and signal transduction. The receptor-like protein kinases (RLKs) are known to act as an important class of cell surface receptors and are involved ...
Xiaoxu Li, Salman Ahmad, Akhtar Ali, Cun Guo, Hong Li, Jing Yu, Yan Zhang, Xiaoming Gao, Yongfeng Guo   +8 more
doaj   +1 more source

Anesthetics may modulate cancer surgical outcome: a possible role of miRNAs regulation

BMC Anesthesiology, 2021
Background microRNAs (miRNAs) are single-stranded and noncoding RNA molecules that control post-transcriptional gene regulation. miRNAs can be tumor suppressors or oncogenes through various mechanism including cancer cell biology, cell-to-cell ...
Masashi Ishikawa, Masae Iwasaki, Atsuhiro Sakamoto, Daqing Ma   +3 more
doaj   +1 more source

Syntenin mediates SRC function in exosomal cell-to-cell communication

Proceedings of the National Academy of Sciences of the United States of America, 2017
Significance Viral-like nanovesicles of endosomal origin, or “exosomes,” are newly recognized vehicles of signals that cells use to communicate, in various systemic diseases, including cancer. Yet the molecular mechanisms that regulate the biogenesis and
N. Imjeti, Kerstin Menck, A. L. Egea-Jimenez, C. Lecointre, F. Lembo, Habib Bouguenina, A. Badache, R. Ghossoub, G. David, S. Roche, P. Zimmermann   +10 more
semanticscholar   +1 more source

Role of noncoding RNA in vascular remodelling [PDF]

, 2016
Purpose of review: Noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are becoming fundamentally important in the pathophysiology relating to injury-induced vascular remodelling.
Baker, Andrew H., Bradshaw, Angela C., Deng, Lin   +2 more
core   +1 more source

Calcium-sensing receptor activation increases cell-cell adhesion and ß-cell function [PDF]

, 2012
Background/Aims: The extracellular calcium-sensing receptor (CaR) is expressed in pancreatic β-cells where it is thought to facilitate cell-to-cell communication and augment insulin secretion.
Bennett, J., Hills, C. E., Liu, K.-K., Siamantouras, E., Squires, P. E., Younis, M. Y.G.   +5 more
core   +2 more sources