Results 81 to 90 of about 1,625,351 (310)
Tip cell overtaking occurs as a side effect of sprouting in computational models of angiogenesis [PDF]
BMC Systems Biology 2015, 9:86, 2015 During angiogenesis, endothelial cells compete for the tip position during angiogenesis: a phenomenon named tip cell overtaking. It is still unclear to what extent tip cell overtaking is a side effect of sprouting or to what extent a biological function.
arxiv +1 more source
Detailed simulations of cell biology with Smoldyn 2.1. [PDF]
, 2010 Most cellular processes depend on intracellular locations and random collisions of individual protein molecules. To model these processes, we developed algorithms to simulate the diffusion, membrane interactions, and reactions of individual molecules ...
Addy, Nathan +3 more
core +2 more sources
Contribution of increasing plasma membrane to the energetic cost of early zebrafish embryogenesis [PDF]
, 2020 © The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Rodenfels, J., Sartori, P., Golfier, S., Nagendra, K., Neugebauer, K. M., & Howard, J.
Golfier, Stefan +5 more
core +1 more source
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
FEBS Letters, EarlyView.The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr +4 more
wiley +1 more source
Heliyon, 2016 The emerging models of human embryonic stem cell (hESC) self-organizing organoids provide a valuable in vitro platform for studying self-organizing processes that presumably mimic in vivo human developmental events. Here we report that through a chemical
Yijie Geng, Bradley Feng
doaj +1 more source
FEBS Letters, EarlyView.The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang +9 more
wiley +1 more source
iScience, 2021 Summary: Protein arginine methyltransferases (PRMTs) catalyze the post-translational monomethylation (Rme1), asymmetric (Rme2a), or symmetric (Rme2s) dimethylation of arginine. To determine the cellular consequences of type I (Rme2a) and II (Rme2s) PRMTs,
Maxim I. Maron +17 more
doaj
, 2020 The cell membrane is a ubiquitous component in mammalian cells which control many vital biological functions. It consists of a phospholipid bilayer with embedded protein molecules which serve to transport molecules between the interior and exterior of ...
Beltramo, Peter
core +1 more source
Proceedings: Regenerative Medicine for Lung Diseases: A CIRM Workshop Report. [PDF]
, 2017 The mission of the California Institute of Regenerative Medicine (CIRM) is to accelerate treatments to patients with unmet medical needs. In September 2016, CIRM sponsored a workshop held at the University of California, Los Angeles, to discuss ...
DeWitt, Natalie D +2 more
core +1 more source
Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase
FEBS Letters, EarlyView.Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka +6 more
wiley +1 more source