Results 1 to 10 of about 1,294,637 (299)

Nucleation of cadherin clusters on cell-cell interfaces

open access: yesScientific Reports, 2022
Cadherins mediate cell-cell adhesion and help the cell determine its shape and function. Here we study collective cadherin organization and interactions within cell-cell contact areas, and find the cadherin density at which a ‘gas-liquid’ phase ...
Neil Ibata, Eugene M. Terentjev
doaj   +4 more sources

Frustration induced phases in migrating cell clusters [PDF]

open access: yesScience Advances, 2017
Collective motion of cells is common in many physiological processes, including tissue development, repair, and tumor formation. Recent experiments have shown that certain malignant cancer cells form clusters in a chemoattractant gradient, which display ...
Copenhagen, Katherine   +5 more
core   +8 more sources

A method to quantitatively characterize the formation and dissociation of tumor cell clusters using light transmission aggregometry [PDF]

open access: yesMolecular Oncology
In this paper, we have modified the workflow of the traditional light transmission aggregometry (LTA) protocol to characterize tumor cell clusters in vitro in a quantifiable and multifaceted manner.
Regina Komal Kottana   +2 more
doaj   +2 more sources

Active Contours Driven by Cellular Neural Networks for Image Segmentation in Biomedical Applications [PDF]

open access: yesRevista Română de Informatică și Automatică, 2021
This paper proposes a novel approach for image segmentation in the context of biomedical applications. The medical images considered for this analysis are both microarray images and images recorded from microfluidics devices. In case of microarray images,
Bogdan BELEAN
doaj   +1 more source

scMoC: single-cell multi-omics clustering [PDF]

open access: yesBioinformatics Advances, 2021
Abstract Motivation Single-cell multi-omics assays simultaneously measure different molecular features from the same cell. A key question is how to benefit from the complementary data available and perform cross-modal clustering of cells.
Mostafa Eltager   +3 more
openaire   +5 more sources

Cartilage cell clusters [PDF]

open access: yesArthritis & Rheumatism, 2010
The formation of new cell clusters is a histological hallmark of arthritic cartilage but the biology of clusters and their role in disease are poorly understood. This is the first comprehensive review of clinical and experimental conditions associated with cluster formation. Genes and proteins that are expressed in cluster cells, the cellular origin of
Martin K, Lotz   +5 more
openaire   +2 more sources

Nascent Adhesion Clustering: Integrin-Integrin and Integrin-Substrate Interactions

open access: yesBiophysica, 2022
Nascent adhesions (NAs) are a general precursor to the formation of focal adhesions (FAs) that provide a fundamental mechanism for cell adhesion that is, in turn, involved in cell proliferation, migration, and mechanotransduction.
Kuanpo Lin, Robert J. Asaro
doaj   +1 more source

Algorithm to identify circulating tumor cell clusters using in vivo flow cytometer [PDF]

open access: yesJournal of Innovative Optical Health Sciences, 2018
Recent studies in oncology have addressed the importance of detecting circulating tumor cell clusters because circulating tumor cell clusters might survive and metastasize more easily than single circulating tumor cells.
Kai Pang   +5 more
doaj   +1 more source

Aggrephagy-related patterns in tumor microenvironment, prognosis, and immunotherapy for acute myeloid leukemia: a comprehensive single-cell RNA sequencing analysis

open access: yesFrontiers in Oncology, 2023
Acute myeloid leukemia (AML) is a complex mixed entity composed of malignant tumor cells, immune cells and stromal cells, with intra-tumor and inter-tumor heterogeneity. Single-cell RNA sequencing enables a comprehensive study of the highly complex tumor
Yan Pan   +7 more
doaj   +1 more source

Sensitivity of EGFR/HER-2 Positive Cells Isolated from Ascitic Fluid of Advanced Ovarian Cancer Patients to EGFR/HER-2 Inhibitors

open access: yesApplied Sciences, 2020
Background: advanced ovarian cancer often presents with ascites. These ascites contain small clusters of cancer cells, which may contribute greatly to the metastatic potential of ovarian cancer in the peritoneal cavity.
Kenny Chitcholtan   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy