Results 31 to 40 of about 1,294,637 (299)

Distinct cell clusters touching islet cells induce islet cell replication in association with over-expression of Regenerating Gene (REG) protein in fulminant type 1 diabetes.

PLoS ONE, 2014
BackgroundPancreatic islet endocrine cell-supporting architectures, including islet encapsulating basement membranes (BMs), extracellular matrix (ECM), and possible cell clusters, are unclear.ProceduresThe architectures around islet cell clusters ...
Kaoru Aida, Sei Saitoh, Yoriko Nishida, Sadanori Yokota, Shinichi Ohno, Xiayang Mao, Daiichiro Akiyama, Shoichiro Tanaka, Takuya Awata, Akira Shimada, Youichi Oikawa, Hiroki Shimura, Fumihiko Furuya, Soichi Takizawa, Masashi Ichijo, Sayaka Ichijo, Jun Itakura, Hideki Fujii, Akinori Hashiguchi, Shin Takasawa, Toyoshi Endo, Tetsuro Kobayashi   +21 more
doaj   +1 more source

An entropy-based metric for assessing the purity of single cell populations

Nature Communications, 2020
Single cell RNA-seq is a powerful method to assign cell identity, but the purity of cell clusters arising from this data is not clear. Here the authors present an entropy-based statistic called ROGUE to quantify the purity of cell clusters, and identify ...
Baolin Liu, Chenwei Li, Ziyi Li, Dongfang Wang, Xianwen Ren, Zemin Zhang   +5 more
doaj   +1 more source

Analysis of regulatory network involved in mechanical induction of embryonic stem cell differentiation [PDF]

, 2012
Embryonic stem cells are conventionally differentiated by modulating specific growth factors in the cell culture media. Recently the effect of cellular mechanical microenvironment in inducing phenotype specific differentiation has attracted considerable ...
Banerjee, I, Jaramillo, M, Kumta, P, Singh, S, Zhang, X   +4 more
core   +4 more sources

Water-soluble hybrid materials based on {Mo₆X₈}⁴⁺ (X = Cl, Br, I) cluster complexes and sodium polystyrene sulfonate [PDF]

, 2017
Development of water-soluble forms of octahedral molybdenum clusters {Mo₆X₈}⁴⁺ (X = Cl, Br, I) is strongly motivated by the tremendous potential that these complexes have for biological applications, namely as agents for bioimaging and photodynamic ...
Brylev, Konstantin, Brylev, Konstantin A., Edeleva, Mariya, Edeleva, Mariya V., Efremova, Olga A., Gyrylova, Svetlana, Gyrylova, Svetlana N., Kitamura, Noboru, Kurskaya, Olga, Kurskaya, Olga G., Mironov, Yuri, Mironov, Yuri V., Shestopalov, Alexander, Shestopalov, Alexander M., Shestopalov, Michael, Shestopalov, Michael A., Solovieva, Anastasiya, Solovieva, Anastasiya O., Svezhentseva, Ekaterina, Svezhentseva, Ekaterina V., Tsygankova, Alphiya, Tsygankova, Alphiya R., Vorotnikov, Yuri, Vorotnikov, Yuri A.   +23 more
core   +1 more source

Ultrastructural Analysis of Inflammatory Breast Cancer Cell Clusters in an Ex Vivo Environment Mechanically Mimicking the Lymph Vascular System

Breast Cancer: Basic and Clinical Research, 2021
Background: Inflammatory breast cancer (IBC) is a rare form of breast cancer with a poor prognosis. IBC is characterized by florid lymphovascular tumor emboli in the skin and the parenchyma of the breast.
Yuka Fujii, Savitri Krishnamurthy, Randa El-Zein   +2 more
doaj   +1 more source

Cell division, differentiation and dynamic clustering

Physica D: Nonlinear Phenomena, 1994
A novel mechanism for cell differentiation is proposed, based on the dynamic clustering in a globally coupled chaotic system. A simple model with metabolic reaction, active transport of chemicals from media, and cell division is found to show three successive stages with the growth of the number of cells; coherent growth, dynamic clustering, and fixed ...
Kaneko, Kunihiko, Yomo, Tetsuya
openaire   +3 more sources

SAME-clustering: Single-cell Aggregated Clustering via Mixture Model Ensemble [PDF]

Nucleic Acids Research, 2019
ABSTRACTClustering is an essential step in the analysis of single cell RNA-seq (scRNA-seq) data to shed light on tissue complexity including the number of cell types and transcriptomic signatures of each cell type. Due to its importance, novel methods have been developed recently for this purpose.
Ruth Huh, Yuchen Yang, Yuchao Jiang, Yin Shen, Yun Li   +4 more
openaire   +2 more sources

Influence of cluster‐period cells in stepped wedge cluster randomized trials

Biometrical Journal, 2022
AbstractStepped wedge cluster randomized trials (SWCRT) are increasingly used for the evaluation of complex interventions in health services research. They randomly allocate treatments to clusters that switch to intervention under investigation at variable time points without returning to control condition. The resulting unbalanced allocation over time
Philipp Mildenberger, Jochem König
openaire   +4 more sources

Human adenocarcinoma cell line sensitivity to essential oil phytocomplexes from pistacia species: A multivariate approach [PDF]

, 2017
Principal component analysis (PCA) multivariate analysis was applied to study the cytotoxic activity of essential oils from various species of the Pistacia genus on human tumor cell lines.
Buriani, Alessandro, Carrara, Maria, Dall'Acqua, Stefano, Fortinguerra, Stefano, Gabbia, Daniela, Innocenti, Gabbriella, Montopoli, Monica, Sorrenti, Vincenzo   +7 more
core   +1 more source

Multi-Objective Optimized Fuzzy Clustering for Detecting Cell Clusters from Single-Cell Expression Profiles [PDF]

Genes, 2019
Rapid advance in single-cell RNA sequencing (scRNA-seq) allows measurement of the expression of genes at single-cell resolution in complex disease or tissue. While many methods have been developed to detect cell clusters from the scRNA-seq data, this task currently remains a main challenge.
Saurav Mallik, Zhongming Zhao
openaire   +2 more sources