The Physics of Living Neural Networks
, 2007 Improvements in technique in conjunction with an evolution of the theoretical and conceptual approach to neuronal networks provide a new perspective on living neurons in culture.
Eckmann, Jean-Pierre +5 more
core +2 more sources
A long-term in vitro silicon-based microelectrode-neuron connection [PDF]
, 1988 A novel method for long-term recording and simulation applicable to cultured neurons has been developed. Silicon-based microelectrodes have been fabricated using integrated-circuit technology and micromachining.
Pine, Jerome +2 more
core +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Hypoxia Induced Downregulation of Na+/H+ Exchanger-1 Activity Decreases Tumor Cell Proliferation
Ankara Üniversitesi Tıp Fakültesi MecmuasıObjectives: Hypoxia and acidosis are the hallmarks of proliferative tumor microenvironment which can modulate the expression and function of Na+/H+ exchanger-1 (NHE1) via hypoxia inducible factor 1 (Hif).
Gül Şimşek, Hilmi Burak Kandilci
doaj +1 more source
An Extensive Method for Maintenance of Sterility in Mammalian Cell Culture Laboratory Routine
Challenges, 2017 Cell culture laboratories are designed to secure sterile environments for biological studies, and its susceptibility to biological contaminants is a major problem for researchers.
Selcen Çelik-Uzuner, Uğur Uzuner
doaj +1 more source
Lattice and Continuum Modelling of a Bioactive Porous Tissue Scaffold
, 2018 A contemporary procedure to grow artificial tissue is to seed cells onto a porous biomaterial scaffold and culture it within a perfusion bioreactor to facilitate the transport of nutrients to growing cells.
Beliaev, Dmitry +3 more
core
Long-Term Culture of Rat Hippocampal Neurons at Low Density in Serum-Free Medium: Combination of the Sandwich Culture Technique with the Three-Dimensional Nanofibrous Hydrogel PuraMatrix [PDF]
, 2014 The primary culture of neuronal cells plays an important role in neuroscience. There has long been a need for methods enabling the long-term culture of primary neurons at low density, in defined serum-free medium. However, the lower the cell density, the
Kaneko Ai +3 more
core +2 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Journal of Oral MicrobiologyObjective The aim of the present study was to characterize the antimicrobial and anti-inflammatory activities of postbiotics from lactic acid bacteria against Porphyromonas gingivalis.Material and methods The anti-P.
Johana R. Naja +6 more
doaj +1 more source