Results 41 to 50 of about 15,811,009 (408)

Growth regulation in Hydra. Relationship between epithelial cell cycle length and growth rate [PDF]

open access: yes, 1984
The relationship between epithelial cell production and growth rate was investigated in Hydra attenuata under different feeding regimes. The increase of epithelial cell number was compared to the duration of the epithelial cell cycle using standard ...
Bosch, Thomas C. G., David, Charles N.
core   +1 more source

Cooperation of the BTB-Zinc finger protein, Abrupt, with cytoskeletal regulators in Drosophila epithelial tumorigenesis

open access: yesBiology Open, 2015
The deregulation of cell polarity or cytoskeletal regulators is a common occurrence in human epithelial cancers. Moreover, there is accumulating evidence in human epithelial cancer that BTB-ZF genes, such as Bcl6 and ZBTB7A, are oncogenic.
Nezaket Turkel   +5 more
doaj   +1 more source

A novel loss-of-function mutation of the voltage-gated potassium channel Kv10.2 involved in epilepsy and autism

open access: yesOrphanet Journal of Rare Diseases, 2022
Background Novel developmental mutations associated with disease are a continuous challenge in medicine. Clinical consequences caused by these mutations include neuron and cognitive alterations that can lead to epilepsy or autism spectrum disorders ...
Jesús Galán-Vidal   +8 more
doaj   +1 more source

Computational challenges of cell cycle analysis using single cell transcriptomics [PDF]

open access: yesarXiv, 2022
The cell cycle is one of the most fundamental biological processes important for understanding normal physiology and various pathologies such as cancer. Single cell RNA sequencing technologies give an opportunity to analyse the cell cycle transcriptome dynamics in an unprecedented range of conditions (cell types and perturbations), with thousands of ...
arxiv  

Cell cycle and differentiation [PDF]

open access: yesCurrent Opinion in Plant Biology, 2004
The development of multicellular organisms relies on the temporal and spatial control of cell proliferation and cell growth. The relationship between cell-cycle progression and development is complex and characterized by mutual dependencies. On the level of the individual cell, this interrelationship has implications for pattern formation and cell ...
Jakoby, M., Schnittger, A.
openaire   +3 more sources

Rescue of DNA damage after constricted migration reveals a mechano-regulated threshold for cell cycle. [PDF]

open access: yes, 2019
Migration through 3D constrictions can cause nuclear rupture and mislocalization of nuclear proteins, but damage to DNA remains uncertain, as does any effect on cell cycle.
Bannister   +77 more
core   +1 more source

Monitoring cytosolic H2O2 fluctuations arising from altered plasma membrane gradients or from mitochondrial activity

open access: yesNature Communications, 2019
Reliable methods of measuring intracellular H2O2 fluctuations are necessary to advance redox biology. Here the authors design a H2O2 sensor based on the fission yeast peroxiredoxin Tpx1 to sense nanomolar fluctuations of intracellular H2O2 in response to
Mercè Carmona   +8 more
doaj   +1 more source

GST‐IVTT pull‐down: a fast and versatile in vitro method for validating and mapping protein–protein interactions

open access: yesFEBS Open Bio, 2022
Over the past few decades, dozens of in vitro methods have been developed to map, investigate and validate protein–protein interactions. However, most of these approaches are time‐consuming and labour‐intensive or require specialised equipment or ...
Zsuzsánna Réthi‐Nagy   +2 more
doaj   +1 more source

Regulation of Cell Cycles

open access: yesJournal of Investigative Dermatology, 1976
Of the major achievements in cell biology during the last 25 years, none is more important than the understanding of regulation of cell cycles. In 1953 two fundamental observations concerning DNA were made. Watson and Crick suggested that the three-dimensional structure of DNA exists as a double helix with specific base pairings, and Howard and Pelc ...
Elizabeth A. Duell   +3 more
openaire   +3 more sources

Cell cycle analysis of primary sponge cell cultures [PDF]

open access: yes, 2011
Proliferation of sponge cells is generally measured via cell counts or viability assays. However, more insight into the proliferative state of a sponge cell population can be obtained from the distribution of the cells over the different phases of the ...
Martens, D.E.   +3 more
core   +3 more sources

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