Results 41 to 50 of about 15,988,239 (410)
Acanthamoeba induces cell-cycle arrest in host cells [PDF]
, 2004 Acanthamoeba can cause fatal granulomatous amoebic encephalitis (GAE) and eye keratitis. However, the pathogenesis and pathophysiology of these emerging diseases remain unclear.
Alizadeh +41 more
core +1 more source
Conditional control of fluorescent protein degradation by an auxin-dependent nanobody
Nature Communications, 2018 Current approaches to conditionally deplete target proteins require site-specific genetic engineering or have poor temporal control. Here the authors overcome these limitations by combining the AID system with nanobodies to reversibly degrade GFP-tagged ...
Katrin Daniel +5 more
doaj +1 more source
Journal of Immunology, 1984 The monoclonal antibody Ki-67 detects a nuclear antigen that is present only in proliferating cells. The aim of the present investigation was to clarify whether the Ki-67 nuclear antigen is restricted in its expression to certain phases of the cell cycle.
J. Gerdes +5 more
semanticscholar +1 more source
Nature Communications, 2016 The small molecule (p)ppGpp is commonly produced by bacteria as a signal of nutrient starvation. Here, Ronneau et al. show that (p)ppGpp accumulation in the model bacterium Caulobacter crescentusis modulated by a nitrogen-related phosphotransferase ...
Séverin Ronneau +3 more
doaj +1 more source
Antioxidants, 2023 Aging is characterized by a number of hallmarks including loss of mitochondrial homeostasis and decay in stress tolerance, among others. Unicellular eukaryotes have been widely used to study chronological aging.
Anna Gröger +5 more
doaj +1 more source
Characterizing stochastic cell cycle dynamics in exponential growth [PDF]
Phys. Rev. E 105, 014420 (2022), 2021 Two powerful and complementary experimental approaches are commonly used to study the cell cycle and cell biology: One class of experiments characterizes the statistics (or demographics) of an unsynchronized exponentially-growing population, while the other captures cell cycle dynamics, either by time-lapse imaging of full cell cycles or in bulk ...
arxiv +1 more source
Metabolic control of cell division in α-proteobacteria by a NAD-dependent glutamate dehydrogenase
Communicative & Integrative Biology, 2016 Prior to initiate energy-consuming processes, such as DNA replication or cell division, cells need to evaluate their metabolic status. We have recently identified and characterized a new connection between metabolism and cell division in the α ...
François Beaufay +2 more
doaj +1 more source
Neoplasia, 2000 In multicellular organisms, cell proliferation and death must be regulated to maintain tissue homeostasis. Many observations suggest that this regulation may be achieved, in part, by coupling the process of cell cycle progression and programmed cell death by using and controlling a shared set of factors.
PUCCI, B., KASTEN, M., GIORDANO, A.
openaire +6 more sources
Growth regulation in Hydra. Relationship between epithelial cell cycle length and growth rate [PDF]
, 1984 The relationship between epithelial cell production and growth rate was investigated in Hydra attenuata under different feeding regimes. The increase of epithelial cell number was compared to the duration of the epithelial cell cycle using standard ...
Bosch, Thomas C. G., David, Charles N.
core +1 more source
Computational challenges of cell cycle analysis using single cell transcriptomics [PDF]
arXiv, 2022 The cell cycle is one of the most fundamental biological processes important for understanding normal physiology and various pathologies such as cancer. Single cell RNA sequencing technologies give an opportunity to analyse the cell cycle transcriptome dynamics in an unprecedented range of conditions (cell types and perturbations), with thousands of ...
arxiv