Results 241 to 250 of about 3,883,823 (304)

Cell Cycle Proteins and Atherosclerosis

Herz, 2000
Progression of the eukaryotic cell through the cell cycle to induce cell proliferation is a fundamental event in developmental growth processes. Specific cell cycle proteins are critical for either inducing or suppressing the cell cycle. These proteins, therefore, have been found to be key players in regulating cell proliferation in diseases like ...
M E, Zettler, G N, Pierce
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Farnesylated proteins and cell cycle progression

Journal of Cellular Biochemistry, 2001
Post-translational modification of proteins by the addition of a farnesyl group is critical for the function of a number of proteins involved in signal transduction. Farnesylation facilitates their membrane association and also promotes protein-protein interaction.
F, Tamanoi, J, Kato-Stankiewicz, C, Jiang, I, Machado, N, Thapar   +4 more
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Retinoblastoma protein and the cell cycle

Current Opinion in Genetics & Development, 1993
Deregulation of the cell cycle may contribute one of the primary mechanisms through which cancer arises. Eukaryotic cell division has been found to be a strictly controlled process, involving response to both positive and negative external signals and assessment of the cell's internal state.
R E, Hollingsworth, C E, Hensey, W H, Lee   +2 more
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Quantification of Cell Cycle-Arresting Proteins

2012
Cellular senescence, which can be defined as a stress response preventing the propagation of cells that have accumulated potentially oncogenic alterations, is invariably associated with a permanent cell cycle arrest. Such an irreversible blockage is mainly mediated by the persistent upregulation of one or more cyclin-dependent kinase inhibitors (CKIs),
Oliver, Kepp, Isabelle, Martins, Laurie, Menger, Mickaël, Michaud, Sandy, Adjemian, Abdul Qader, Sukkurwala, Lorenzo, Galluzzi, Guido, Kroemer   +7 more
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Nuclear Proteins And The Cell Cycle

1972
Publisher Summary This chapter discusses the biochemistry of the cell cycle in continuously dividing cells and the biochemical events that are described in G0 cells stimulated to proliferate. It also focuses on the proteins of the mammalian nucleus and the role that they may play in the control of cellular proliferation.
G, Stein, R, Baserga
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Protein kinases and cell cycle control

Seminars in Cell Biology, 1994
Protein kinases play a central role in the regulation of the eukaryotic cell cycle. Recent research has concentrated on a particular family of protein kinases, the cyclin-dependent kinases (CDKs), and their involvement in regulating particular cell cycle transitions, such as the initiation of DNA synthesis (S phase) or of cell division (mitosis).
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Protein synthesis during the cell cycle oF L5178Y cells

Experimental Cell Research, 1973
Abstract There are two peaks of 3H-leucine incorporation in the cell cycle of L5178Y cells. The first, during S stage, corresponds to a peak of 3H-leucine incorporation into the nuclear fraction. The second, during S or early G2, corresponds to a peak of 3H-leucine incorporation into the mitochondrial fraction. The rate of protein synthesis is unique
Roti roti, J, Okada, S, Eberle, H
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Recent Patents on Cell Cycle Regulatory Proteins

Recent Patents on Biotechnology, 2009
Cell cycle progression and cell division are driven by the sequential activation of a group of serine-threonine kinases called cyclin-dependent kinases (Cdks). Multiple Cdks control the cell cycle in mammals and have been long considered essential for normal proliferation, development and homeostasis.
Julius L C, Chulu, Hung J, Liu
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The retinoblastoma protein and cell cycle regulation

Trends in Genetics, 1992
Although the precise function of the retinoblastoma gene product, p110RB1, remains unknown, recent data suggest that it plays a role in the control of cellular proliferation by regulating transcription of genes required for a cell to enter or stay in a quiescent or G0 state, or for progression through the G1 phase of the cell cycle.
P A, Hamel, B L, Gallie, R A, Phillips
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