Results 21 to 30 of about 3,883,823 (304)

Inhibition of prostate cancer growth by solanine requires the suppression of cell cycle proteins and the activation of ROS/P38 signaling pathway. [PDF]

Cancer Med, 2016
Solanine, a naturally steroidal glycoalkaloid in nightshade (Solanum nigrum Linn.), can inhibit proliferation and induce apoptosis of tumor cells. However, the mechanism of solanine‐suppressing prostate cancer cell growth remains to be elucidated.
Pan B, Zhong W, Deng Z, Lai C, Chu J, Jiao G, Liu J, Zhou Q.   +7 more
europepmc   +2 more sources

Copper induces cell death by targeting lipoylated TCA cycle proteins

Science, 2022
Copper is an essential cofactor for all organisms, and yet it becomes toxic if concentrations exceed a threshold maintained by evolutionarily conserved homeostatic mechanisms. How excess copper induces cell death, however, is unknown.
Peter Tsvetkov, S. Coy, Boryana Petrova, Margaret B. Dreishpoon, A. Verma, M. Abdusamad, J. Rossen, Lena M Joesch-Cohen, Ranad Humeidi, R. Spangler, J. Eaton, Evgeni M. Frenkel, M. Kocak, S. M. Corsello, S. Lutsenko, Naama Kanarek, S. Santagata, T. Golub   +17 more
semanticscholar   +1 more source

Maternal Toxoplasma gondii infection affects proliferation, differentiation and cell cycle regulation of retinal neural progenitor cells in mouse embryo

Frontiers in Cellular Neuroscience, 2023
BackgroundToxoplasmosis affects one third of the world population and has the protozoan Toxoplasma gondii as etiological agent. Congenital toxoplasmosis (CT) can cause severe damage to the fetus, including miscarriages, intracranial calcification ...
Viviane Souza de Campos, Viviane Souza de Campos, Camila Feitosa Magalhães, Barbara Gomes da Rosa, Carolina Moreira dos Santos, Lucianne Fragel-Madeira, Danniel Pereira Figueiredo, Karin C. Calaza, Daniel Adesse, Daniel Adesse   +9 more
doaj   +1 more source

Cuproptosis: lipoylated TCA cycle proteins-mediated novel cell death pathway

Signal Transduction and Targeted Therapy, 2022
In a recent study published in Science , Tsvetkov et al 1 . shed a light on a new form of cell death, copper-dependent cell death (termed cuproptosis). They de fi ned “ cuproptosis ” as a nonapoptotic cell death pathway. They have demonstrated that copper
Suqing Li, L. Bu, Lulu Cai
semanticscholar   +1 more source

Cell Cycle Control by Optogenetically Regulated Cell Cycle Inhibitor Protein p21

Biology, 2023
The progression through the cell cycle phases is driven by cyclin-dependent kinases and cyclins as their regulatory subunits. As nuclear protein, the cell cycle inhibitor p21/CDKN1A arrests the cell cycle at the growth phase G1 by inhibiting the activity of cyclin-dependent kinases.
Levin Lataster, Hanna Mereth Huber, Christina Böttcher, Stefanie Föller, Ralf Takors, Gerald Radziwill   +5 more
openaire   +5 more sources

Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons

Frontiers in Cell and Developmental Biology, 2021
Proper regulation of neuronal morphological changes is essential for neuronal migration, maturation, synapse formation, and high-order function. Many cytoplasmic proteins involved in the regulation of neuronal microtubules and the actin cytoskeleton have
Remi Akagawa, Yo-ichi Nabeshima, Takeshi Kawauchi, Takeshi Kawauchi   +3 more
doaj   +1 more source

Cell Cycle and Related Protein [PDF]

Disease Markers, 2007
John Farleya, Laurent Ozbunb, Goli Samimic and Michael J. Birrerb,∗ Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences 4301 Jones Bridge Road, Bethesda, MD 20814, USA Cell and Cancer Biology Department, Medicine Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA Cancer ...
Farley, John, Ozbun, Laurent, Samimi, Goli, Birrer, Michael J.   +3 more
openaire   +2 more sources

Simulated Microgravity Induces the Proliferative Inhibition and Morphological Changes in Porcine Granulosa Cells

Current Issues in Molecular Biology, 2021
Astronauts are always faced with serious health problems during prolonged spaceflights. Previous studies have shown that weightlessness significantly affects the physiological function of female astronauts, including a change in reproductive hormones and
Truong Xuan Dai, Hoang Nghia Son, Ho Nguyen Quynh Chi, Hoang Nghia Quang Huy, Nguyen Thai Minh, Nguyen Thi Thuy Tram, Nguyen Thi Thuong Huyen, To Minh Quan, Doan Chinh Chung, Truong Hai Nhung, Tran Thi Minh, Tran Hong Diem, Nguyen Thi Phuong Mai, Le Thanh Long   +13 more
doaj   +1 more source

Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins. [PDF]

PLoS ONE, 2013
Cell proliferation involves dramatic changes in DNA metabolism and cell division, and control of DNA replication, mitosis, and cytokinesis have received the greatest attention in the cell cycle field.
Karen R Lane, Yanbao Yu, Patrick E Lackey, Xian Chen, William F Marzluff, Jeanette Gowen Cook   +5 more
doaj   +1 more source

Switching the Cell Cycle. Kip-Related Proteins in Plant Cell Cycle Control [PDF]

Plant Physiology, 2005
During the development of multicellular organisms, many different cell types are created. These display characteristic cell cycle programs that can radically change during the organism's lifetime ([Jakoby and Schnittger, 2004][1]; [Fig. 1][2]).
Verkest, Aurine, Weinl, Christina, Inzé, Dirk, De Veylder, Lieven, Schnittger, Arp   +4 more
openaire   +4 more sources