Results 31 to 40 of about 3,883,823 (304)
Cell cycle regulation: p53-p21-RB signaling
Cell Death and Differentiation, 2022 The retinoblastoma protein RB and the transcription factor p53 are central tumor suppressors. They are often found inactivated in various tumor types. Both proteins play central roles in regulating the cell division cycle. RB forms complexes with the E2F
K. Engeland
semanticscholar +1 more source
Cells, 2022 Psoriasis is a persistent T-cell-supported inflammatory cutaneous disorder, which is defined by a significant expansion of basal cells in the epidermis. Cell cycle and STAT genes that control cell cycle progression and viral infection have been revealed ...
Subhashini Dorai, Daniel Alex Anand
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S100A8 calcium-binding expression in radicular and dentigerous cysts and in keratocystic odontogenic tumors [PDF]
Stomatološki glasnik Srbije, 2008 Introduction: Recently the term Keratocystic Odontogenic Tumor (KCOT) has been recommended for Odontogenic Keratocysts (OKC) to address the neoplastic nature of the lesion compared to radicular and dentigerous cysts.
Iezzi Giovanna +7 more
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Tumor suppressors and cell-cycle proteins in lung cancer. [PDF]
Patholog Res Int, 2011 The cell cycle is the cascade of events that allows a growing cell to duplicate all its components and split into two daughter cells. Cell cycle progression is mediated by the activation of a highly conserved family of protein kinases, the cyclin ...
Baldi A +5 more
europepmc +2 more sources
Fluorescent Reporters and Biosensors for Probing the Dynamic Behavior of Protein Kinases
Proteomes, 2015 Probing the dynamic activities of protein kinases in real-time in living cells constitutes a major challenge that requires specific and sensitive tools tailored to meet the particular demands associated with cellular imaging.
Juan A. González-Vera, May C. Morris
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Dynamic proteomics of human protein level and localization across the cell cycle. [PDF]
PLoS ONE, 2012 Regulation of proteins across the cell cycle is a basic process in cell biology. It has been difficult to study this globally in human cells due to lack of methods to accurately follow protein levels and localizations over time. Estimates based on global
Shlomit Farkash-Amar +8 more
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The Influence of Cell Cycle Regulation on Chemotherapy
International Journal of Molecular Sciences, 2021 Cell cycle regulation is orchestrated by a complex network of interactions between proteins, enzymes, cytokines, and cell cycle signaling pathways, and is vital for cell proliferation, growth, and repair.
Ying Sun, Yang Liu, Xiaoli Ma, Hao Hu
semanticscholar +1 more source
Cell cycle regulatory proteins in glomerular disease [PDF]
Kidney International, 1999 Evidence is accumulating that directly responsible for the rate of progression of glomerular disease are specific positive (cyclins and cyclin-dependent kinases) and negative (cyclin-kinase inhibitors) cell cycle regulatory proteins. The challenge for nephrologists is to determine which ones are expressed in renal disease and their precise role in ...
S J, Shankland, M, Al'Douahji
openaire +4 more sources
Cell Division, 2012 The retinoblastoma (RB) family of proteins are found in organisms as distantly related as humans, plants, and insects. These proteins play a key role in regulating advancement of the cell division cycle from the G1 to S-phases.
Henley Shauna A, Dick Frederick A
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Expression of regulatory proteins and proliferative activity in relation to phenotypic characteristics of upper urothelial carcinoma [PDF]
Vojnosanitetski Pregled, 2011 Background/Aim. Deregulation of the normal cell cycle is common in upper urothelial carcinoma (UUC). The aim of this study was to investigate the expression of regulatory proteins of the cell cycle (p53, p16, cyclin D1, HER-2) and proliferative Ki-67 ...
Dolićanin Zana +6 more
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