Results 41 to 50 of about 3,883,823 (304)
OncoTargets and Therapy, 2018 Introduction Zwint, a centromere-complex component required for the mitotic spindle checkpoint, has been reported to be overexpressed in different human cancers, but it has not been studied in human hepatocellular carcinoma (HCC).
Hanning Ying +5 more
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Drug targets for cell cycle dysregulators in leukemogenesis: in silico docking studies. [PDF]
PLoS ONE, 2014 Alterations in cell cycle regulating proteins are a key characteristic in neoplastic proliferation of lymphoblast cells in patients with Acute Lymphoblastic Leukemia (ALL).
Archana Jayaraman, Kaiser Jamil
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Journal of Neuroinflammation, 2012 Traumatic spinal cord injury (SCI) induces secondary tissue damage that is associated with astrogliosis and inflammation. We previously reported that acute upregulation of a cluster of cell-cycle-related genes contributes to post-mitotic cell death and ...
Junfang Wu +5 more
semanticscholar +1 more source
Cell‐cycle‐dependent, differential prenylation of proteins [PDF]
European Journal of Biochemistry, 1991 Isoprenylated proteins related to cell growth have been detected during proliferation. Since cholesterogenesis (isoprenoid synthesis) is mandatory for cell proliferation, the observation of a temporally coordinated protein prenylation during the cell division cycle might constitute obligatory processes in the signalling pathway for initiating DNA ...
L, Sepp-Lorenzino, S, Rao, P S, Coleman
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Ectopic Cell Cycle Proteins Predict the Sites of Neuronal Cell Death in Alzheimer’s Disease Brain
Journal of Neuroscience, 1998 Alzheimer’s disease (AD) is a major dementing illness characterized by regional concentrations of senile plaques, neurofibrillary tangles, and extensive neuronal cell death.
J. Busser, D. Geldmacher, K. Herrup
semanticscholar +1 more source
The crosstalk between non-coding RNAs and cell-cycle events: A new frontier in cancer therapy
Molecular Therapy: OncologyThe cell cycle comprises sequential events during which a cell duplicates its genome and divides it into two daughter cells. This process is tightly regulated to ensure that the daughter cell receives identical copied chromosomal DNA and that any errors ...
Anup S. Pathania +5 more
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Dynamical Analysis of Yeast Cell Cycle Using a Stochastic Markov Model
مجله انفورماتیک سلامت و زیست پزشکی, 2021 Introduction: The cell cycle network is responsible of control, growth and proliferation of cells. The relationship between the cell cycle network and cancer emergence, and the complex reciprocal interactions between genes/proteins calls for ...
Sajad Shafiekhani +4 more
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eLife, 2017 Ubiquilins (Ubqlns) are a family of ubiquitin receptors that promote the delivery of hydrophobic and aggregated ubiquitinated proteins to the proteasome for degradation.
Alexandra M Whiteley +16 more
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Modelling how plant cell-cycle progression leads to cell size regulation.
PLoS Computational Biology, 2023 Populations of cells typically maintain a consistent size, despite cell division rarely being precisely symmetrical. Therefore, cells must possess a mechanism of "size control", whereby the cell volume at birth affects cell-cycle progression.
Daniel Williamson +4 more
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Cell cycle-dependent variations in protein concentration [PDF]
Nucleic Acids Research, 2009 Computational modeling of biological systems has become an effective tool for analyzing cellular behavior and for elucidating key properties of the intricate networks that underlie experimental observations. While most modeling techniques rely heavily on the concentrations of intracellular molecules, little attention has been paid to tracking and ...
Cookson, Natalie A. +3 more
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