Results 41 to 50 of about 1,825,024 (378)

Robust circadian clocks from coupled protein modification and transcription-translation cycles [PDF]

P Natl Acad Sci Usa (2010) vol. 107 (52) pp. 22540-5, 2010
The cyanobacterium Synechococcus elongatus uses both a protein phosphorylation cycle and a transcription-translation cycle to generate circadian rhythms that are highly robust against biochemical noise. We use stochastic simulations to analyze how these cycles interact to generate stable rhythms in growing, dividing cells.
arxiv   +1 more source

The cyclin-dependent kinase inhibitor Orysa;KRP1 plays an important role in seed development of rice [PDF]

, 2006
Kip-related proteins (KRPs) play a major role in the regulation of the plant cell cycle. We report the identification of five putative rice (Oryza sativa) proteins that share characteristic motifs with previously described plant KRPs.
Barrôco, Rosa Maria, Beemster, Gerrit, Broekaert, Willem F, De Veylder, Lieven, De Wolf, Joris, Droual, Anne-Marie, Frankard, Valerie, Inzé, Dirk, Mironov, Vladimir, Nguyen, Long, Peerbolte, Rindert, Peres, Adrian   +11 more
core   +3 more sources

Chromosome Segregation Proteins as Coordinators of Cell Cycle in Response to Environmental Conditions

Frontiers in Microbiology, 2020
Chromosome segregation is a crucial stage of the cell cycle. In general, proteins involved in this process are DNA-binding proteins, and in most bacteria, ParA and ParB are the main players; however, some bacteria manage this process by employing other ...
Monika Pióro, Dagmara Jakimowicz
doaj   +1 more source

Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2

eLife, 2021
Cell cycle gene expression programs fuel proliferation and are universally dysregulated in cancer. The retinoblastoma (RB)-family of proteins, RB1, RBL1/p107, and RBL2/p130, coordinately represses cell cycle gene expression, inhibiting proliferation, and
Taylor P Enrico, Wayne Stallaert, Elizaveta T Wick, Peter Ngoi, Xianxi Wang, Seth M Rubin, Nicholas G Brown, Jeremy E Purvis, Michael J Emanuele   +8 more
doaj   +1 more source

Control of protein-based pattern formation via guiding cues [PDF]

arXiv, 2022
Proteins control many vital functions in living cells, such as cell growth and cell division. Reliable coordination of these functions requires the spatial and temporal organizaton of proteins inside cells, which encodes information about the cell's geometry and the cell-cycle stage.
arxiv  

Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential [PDF]

, 2016
The Karyopherin superfamily is a major class of soluble transport receptors consisting of both import and export proteins. The trafficking of proteins involved in transcription, cell signalling and cell cycle regulation among other functions across the ...
Aggarwal, Albee, Alnabulsi, Alshareeda, Altan, Angus, Behrens, Bernis, Blower, Brinkmann, Brinkmann, Cansizoglu, Chang, Christiansen, Dahl, Das, Dasso, Depping, Dikovskaya, Forbes, Gluz, Gontan, Gorlich, Gousias, Gousias, Gousias, Grupp, Gruss, Hashimoto, Hintersteiner, Hu, Huang, Huang, Huang, Hutchins, Hügel, Ishizawa, Jensen, Jiang, Kahle, Kau, Kazim, Kim, Kimura, King, Knauer, Kojima, Kosugi, Kudo, Kurisaki, Kutay, Kuusisto, Kuusisto, Lapalombella, Latvia, Lau, Laurila, Li, Liang, Liao, Lin, Lin, Lorenzato, Ma, Marfori, Martens-de Kemp, Melo, Mortezavi, Mosammaparast, Muller, Nevins, Noske, Parikh, Poon, Pumroy, Quan, Quensel, Rensen, Sakai, Scherf, Shen, Shi, Shiraki, Sillje, Smith, Smith, Soderholm, Song, Stawerski, Stella Tsai, Stewart, Tai, Torgerson, Turner, Turner, Wagstaff, Wang, Wang, Wang, Watt, Watt, Watt, Wellmann, Wiese, Winkler, Winnepenninckx, Wu, Yan, Yang, Yao, Yoshitake, Yu, Zender, Zheng, Zhou, Zhu, Zhu, Zienkiewicz   +117 more
core   +1 more source

Growth Arrest Triggers Extra-Cell Cycle Regulatory Function in Neurons: Possible Involvement of p27kip1 in Membrane Trafficking as Well as Cytoskeletal Regulation

Frontiers in Cell and Developmental Biology, 2019
Cell cycle regulation is essential for the development of multicellular organisms, but many cells in adulthood, including neurons, exit from cell cycle. Although cell cycle-related proteins are suppressed after cell cycle exit in general, recent studies ...
Takeshi Kawauchi, Takeshi Kawauchi, Yo-ichi Nabeshima   +2 more
doaj   +1 more source

Regulation of Sp1 by cell cycle related proteins [PDF]

Cell Cycle, 2008
Sp1 transcription factor regulates the expression of multiple genes, including the Sp1 gene itself. We analyzed the ability of different cell cycle regulatory proteins to interact with Sp1 and to affect Sp1 promoter activity. Using an antibody array, we observed that CDK4, SKP2, Rad51, BRCA2 and p21 could interact with Sp1 and we confirmed these ...
Tapias Soler, Alicia, Ciudad i Gómez, Carlos Julián, Roninson, Igor B., Noé Mata, Verónica   +3 more
openaire   +4 more sources

Asynchronous nuclear division cycles in multinucleated cells [PDF]

, 2006
Synchronous mitosis is common in multinucleated cells. We analyzed a unique asynchronous nuclear division cycle in a multinucleated filamentous fungus, Ashbya gossypii.
Gladfelter, A. S., Hungerbuehler, A. K., Philippsen, P.   +2 more
core   +2 more sources

PIN1 in Cell Cycle Control and Cancer

Frontiers in Pharmacology, 2018
Cell cycle progression is tightly controlled by many cell cycle-regulatory proteins that are in turn regulated by a family of cyclin-dependent kinases (CDKs) through protein phosphorylation. The peptidyl-prolyl cis/trans isomerase PIN1 provides a further
Chi-Wai Cheng, Eric Tse
doaj   +1 more source