Results 131 to 140 of about 375,323 (262)

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection against Pseudorabies Virus

Advanced Science, EarlyView.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun, Jianbo Liu, Shi‐Jia Xu, Meng‐Xin Wang, Hongliang Zhang, Yanhe Zhang, Zhi‐Jun Tian, Jin‐Mei Peng, Xin Yin, Tong‐Qing An, Xue‐Hui Cai, Yan‐Dong Tang   +11 more
wiley   +1 more source

Cell Envelope Remodeling and Lipid Metabolism Coordinate Extracellular Vesicle Output in Mycobacterium Tuberculosis. [PDF]

J Extracell Biol
Serrano-Mestre JL, Lerma L, Vázquez-Iniesta L, Salgueiro-Toledo VC, Palacios A, Alebouyeh S, Doddi A, Elortza F, Azkargorta M, Sampedro L, Atondo E, Pacual-Itoiz MÁ, Mayer O, Westwood T, Jacobs WR, Prados-Rosales R.   +15 more
europepmc   +1 more source

Impurity Tolerance in LiFePO4 Cathodes: Contrasting Structural, Electronic, and Electrochemical Roles of Residual Ni and Cr

Advanced Science, EarlyView.
Impurity tolerance in LiFePO4 cathodes varies strongly with impurity type and content. Low Ni levels are accommodated within the lattice with minimal structural disruption, whereas higher Ni contents introduce antisite disorder. In contrast, Cr impurities segregate from the LiFePO4 framework, blocking lithium‐ion pathways and leading to inferior ...
Minjin Kim, Hyerin Jeon, Jinhee Lee, Jinsub Choi   +3 more
wiley   +1 more source

Beyond Percolation: Graphene‐Enabled Network Reinforcement Enhances Thermal Transport in Paraffin Phase‐Change Composites

Advanced Science, EarlyView.
Expanded‐graphite/graphene‐nanoplatelet hybrids deliver a near‐order‐of‐magnitude thermal‐conductivity enhancement in paraffin phase‐change materials. A microCT‐informed 3D modeling framework resolves the percolating EG backbone and captures sub‐voxel GNP enrichment, quantitatively linking microstructure to heat flow and revealing a graphene‐enabled ...
Thomas Hoke, Jackson Hoke, Shucheng Guo, Brittany Chan, Xi Chen   +4 more
wiley   +1 more source

Host-driven remodelling of the <i>Staphylococcus aureus</i> cell envelope: mechanisms, consequences and therapeutic implications. [PDF]

Microbiology (Reading)
Ledger EVK.
europepmc   +1 more source

A new role for lipoproteins LpqZ and FecB in orchestrating mycobacterial cell envelope biogenesis. [PDF]

mBio
Lissner R, Franklin A, Benedict ST, Charitou V, Speer A, Knol J, Jimenez C, Moynihan PJ, Nejentsev S, Kuijl C, Bitter W.   +10 more
europepmc   +2 more sources

mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer

Advanced Science, EarlyView.
Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu, Ci‐ming Sun, Sui‐xian Zhang, Rui Li, Chen‐fei Wu, Zai‐shan Lin, Li Li, Run‐zhe Chen, Qi‐wen Li, Yuan‐yuan Chen, Xuan Li, Ming Chen   +11 more
wiley   +1 more source

Revealing Cell Envelope Heterogeneity in Two Stable <i>Escherichia coli</i> L-Forms. [PDF]

Int J Mol Sci
Xu B, Zhang Y, Liu Y, Hoischen C, Westermann M, Kashiwagi A, Kato T, Yomo T, Xu J.   +8 more
europepmc   +1 more source

An Integrated DNA Nanoprobe for Intranuclear Imaging and in Situ Profiling of OGG1 Activity

Advanced Science, EarlyView.
The TP‐SA nanoprobe, integrating an AS1411 aptamer for nuclear delivery and a FRET array for signal amplification, enables real‐time tracking of nuclear OGG1 activity. It reveals cell‐line‐specific basal OGG1 levels and shows clinical promise using pneumonia patients’ lavage fluid.
Mingzhu Zhao, Xuemei Sun, He Li, Bangming Wang, Mengting Pan, Zhen Ma, Rong‐Mei Kong, Weiheng Kong, Yan Zhao, Fengli Qu   +9 more
wiley   +1 more source

The Mycobacterial Cell Envelope

Journal of Pharmacy and Pharmacology, 1997
Gurdyal S Besra, Patrick J Brennan
openaire   +1 more source