Results 221 to 230 of about 6,713,855 (257)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Evaluating Islet Cell Isolation and Transplantation From Donors Following Medical Assistance in Dying. [PDF]

Transplant Direct
Parente A, Verhoeff K, Kin T, Hefler J, Marfil-Garza BA, Sanchez-Fernandez N, Lam A, Lyon J, O'Gorman D, Dajani KZ, Anderson BL, Bigam DL, MacDonald PE, Shapiro AMJ.   +13 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Modified human skin cell isolation protocol and its influence on keratinocyte and melanocyte culture. [PDF]

Regen Ther
Liu Z, Jin S, Cheng D, Chen H, Wang Y, Ji C, Yan Z, Fang X, Xiao S, Bi X.   +9 more
europepmc   +1 more source

Candidate stem cell isolation and transplantation in Hexacorallia

, 2022
Talice S, Barkan S, Snyder G, Ottolenghi A, Eliachar S, Ben-Romano R, Oisher S, Sharoni T, Lewandowska M, Sultan E, Goldstein O, Aharoni R, Hadad U, Davis C, Moran Y, Gershoni-Yahalom O, Traylor-Knowles N, Rosental B.   +17 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Methods for cell isolation and analysis of the highly regenerative tunicate Polycarpa mytiligera

, 2023
gordon T, Hendin N, Wurtzel O.
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Mesenchymal stromal cell isolation from pond slider (<i>Trachemys scripta</i>) adipose tissue obtained during routine neutering: a model for turtle species. [PDF]

Front Vet Sci
Andreoli V, Vetere A, Conti V, Gavezzoli M, Berni P, Ramoni R, Basini G, Nardini G, Pelizzone I, Grolli S, Di Ianni F.   +10 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source