Results 11 to 20 of about 400,889 (317)

c-Jun as a one-way valve at the naive to primed interface

Cell & Bioscience, 2023
Background c-Jun is a proto-oncogene functioning as a transcription factor to activate gene expression under many physiological and pathological conditions, particularly in somatic cells.
Dongwei Li, Ling Luo, Lin Guo, Chuman Wu, Ran Zhang, Yuling Peng, Menghua Wu, Junqi Kuang, Yan Li, Yudan Zhang, Jun Xie, Wenxiu Xie, Rui Mao, Gang Ma, Xiuling Fu, Jiekai Chen, Andrew P. Hutchins, Duanqing Pei   +17 more
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Protocol for isolation and proteostatic analysis of sub-populations of spermatogenic cells in mouse

STAR Protocols, 2022
Summary: Spermatogenesis generates heterologous cell populations which, if not distinguished clearly, often hinder mechanistic and etiological studies.
Qianxing Zou, Lele Yang, Huayu Qi
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The NuRD complex cooperates with SALL4 to orchestrate reprogramming

Nature Communications, 2023
Cell fate decision involves rewiring of the genome, but remains poorly understood at the chromatin level. Here, we report that chromatin remodeling complex NuRD participates in closing open chromatin in the early phase of somatic reprogramming.
Bo Wang, Chen Li, Jin Ming, Linlin Wu, Shicai Fang, Yi Huang, Lihui Lin, He Liu, Junqi Kuang, Chengchen Zhao, Xingnan Huang, Huijian Feng, Jing Guo, Xuejie Yang, Liman Guo, Xiaofei Zhang, Jiekai Chen, Jing Liu, Ping Zhu, Duanqing Pei   +19 more
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SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation

Cell & Bioscience, 2021
Background Linear ubiquitination is a novel type of ubiquitination that plays important physiological roles in signalling pathways such as tumour necrosis factor (TNF) signalling.
Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang   +5 more
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Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis

iScience, 2021
Summary: Maintaining proteostasis is important for animal development. How proteostasis influences spermatogenesis that generates male gametes, spermatozoa, is not clear.
Qianxing Zou, Lele Yang, Ruona Shi, Yuling Qi, Xiaofei Zhang, Huayu Qi   +5 more
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Diversity Among Cyanobacterial Photosystem I Oligomers

Frontiers in Microbiology, 2022
Unraveling the oligomeric states of the photosystem I complex is essential to understanding the evolution and native mechanisms of photosynthesis. The molecular composition and functions of this complex are highly conserved among cyanobacteria, algae ...
Ming Chen, Xuan Liu, Yujie He, Ningning Li, Ningning Li, Ningning Li, Jun He, Jun He, Ying Zhang, Ying Zhang, Ying Zhang   +10 more
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MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy

Cell Reports, 2023
Summary: Autophagy is a fundamental biological process critical to all eukaryotic cellular life. Although autophagy has been increasingly studied, how its process is precisely coordinated remains an open question. ATG14 (ATG14L/Barkor) is known to play a
Xue Shi, Wenfeng Wu, Zhenhuan Feng, Peiyang Fan, Ruona Shi, Xiaofei Zhang   +5 more
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Forkhead box family transcription factors as versatile regulators for cellular reprogramming to pluripotency

Cell Regeneration, 2021
Forkhead box (Fox) transcription factors play important roles in mammalian development and disease. However, their function in mouse somatic cell reprogramming remains unclear.
Meijun Fu, Huan Chen, Zepo Cai, Yihang Yang, Ziyu Feng, Mengying Zeng, Lijun Chen, Yue Qin, Baomei Cai, Pinghui Zhu, Chunhua Zhou, Shengyong Yu, Jing Guo, Jing Liu, Shangtao Cao, Duanqing Pei   +15 more
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Identifying transposable element expression dynamics and heterogeneity during development at the single-cell level with a processing pipeline scTE

Nature Communications, 2021
How transposable elements (TE) contribute to cell fate changes is unclear. Here, the authors generate a pipeline to quantify TE expression from single cell data.
Jiangping He, Isaac A. Babarinde, Li Sun, Shuyang Xu, Ruhai Chen, Junjie Shi, Yuanjie Wei, Yuhao Li, Gang Ma, Qiang Zhuang, Andrew P. Hutchins, Jiekai Chen   +11 more
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A developmental framework linking neurogenesis and circuit formation in the Drosophila CNS

eLife, 2021
The mechanisms specifying neuronal diversity are well characterized, yet it remains unclear how or if these mechanisms regulate neural circuit assembly.
Brandon Mark, Sen-Lin Lai, Aref Arzan Zarin, Laurina Manning, Heather Q Pollington, Ashok Litwin-Kumar, Albert Cardona, James W Truman, Chris Q Doe   +8 more
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