Results 31 to 40 of about 712,102 (304)
The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in the C. elegans embryo [PDF]
, 2005 Maternal and zygotic activities of the homeodomain protein PAL-1 specify the identity and maintain the development of the multipotent C blastomere lineage in the C. elegans embryo. To identify PAL-1 regulatory target genes, we used microarrays to compare
Baugh, L. Ryan +7 more
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Nature Communications, 2021 How transposable elements (TE) contribute to cell fate changes is unclear. Here, the authors generate a pipeline to quantify TE expression from single cell data.
Jiangping He +11 more
doaj +1 more source
Cell Identification and Cell Lineage Analysis [PDF]
, 2011 Caenorhabditis elegans is uniquely suited to the analysis of cell lineage patterns. C. elegans has a small number of somatic cells whose position and morphology are almost invariant from animal to animal. Because C. elegans is virtually transparent, cells can be identified in live animals using a simple bright-field microscopy technique, Nomarski ...
Claudiu A, Giurumescu +1 more
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A developmental framework linking neurogenesis and circuit formation in the Drosophila CNS
eLife, 2021 The mechanisms specifying neuronal diversity are well characterized, yet it remains unclear how or if these mechanisms regulate neural circuit assembly.
Brandon Mark +8 more
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Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1985 Fixed lineages are the extreme manifestation of the interrelations between cell division pattern, spatial organization and cell differentiation occurring in embryonic development. These relationships are discussed in the light of recent new detailed descriptions of lineages, experimental perturbations and genetic analysis.
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Developmental Biology, 1992 For many years the mechanisms by which skeletal muscles in higher vertebrates come to be composed of diverse fiber types distributed in distinctive patterns has interested cell and developmental biologists. The fiber composition of skeletal muscles varies from class to class and from muscle to muscle within the vertebrates.
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Tracing cell-lineage histories [PDF]
Nature Reviews Genetics, 2018 Three new studies in Nature and Nature Biotechnology report methods for dissecting transcriptomic cell phenotypes and lineage history simultaneously by combining single-cell RNA sequencing (scRNA-seq) with CRISPR-based lineage tracing.
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Systemic mastocytosis with associated myeloproliferative disease and precursor B lymphoblastic leukaemia with t(13;13)(q12;q22) involving FLT3. [PDF]
, 2008 Systemic mastocytoses represent neoplastic proliferations of mast cells. In about 20% of cases systemic mastocytoses are accompanied by clonal haematopoietic non-mast cell-lineage disorders, most commonly myeloid neoplasms.
Dirnhofer, S. +7 more
core +1 more source
eLife, 2022 In recent years, live-imaging techniques have been developed for the adult midgut of Drosophila melanogaster that allow temporal characterization of key processes involved in stem cell and tissue homeostasis.
Marco Marchetti +2 more
doaj +1 more source
Cell lineage specification at single cell resolution [PDF]
Stem Cell Investigation, 2017 Single cell technology has been widely used in developmental and stem cell biology. In mouse, single cell transcriptome has revealed the cell lineage specification in pre-implantation and post-implantation stage embryo. Now Mohammed et al. investigated the dynamic cell fate commitment during the transition from peri-implantation to early post ...
Jian, Yang, Pentao, Liu
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