Results 91 to 100 of about 12,335,534 (353)

The modulation of actin dynamics via atypical Protein Kinase-C activated Cofilin regulates metastasis of colorectal cancer cells

Cell Adhesion & Migration, 2019
Colorectal cancer (CRC) is the third most common cancer in the United States. The exact mechanism of CRC cells metastasis is poorly understood. Actin polymerization is thought to be an initial step in the cancer cell motility cycle which drives the ...
S M Anisul Islam, Rekha Patel, Raja Reddy Bommareddy, Khandker Mohammad Khalid, Mildred Acevedo-Duncan   +4 more
doaj   +1 more source

Not all (cells) who wander are lost: Upstream migration as a pervasive mode of amoeboid cell motility [PDF]

, 2023
Alexander Buffone, Daniel A. Hammer, Sarah Hyun Ji Kim, Nicholas R. Anderson, Ai Mochida, Dong-hun Lee, Subham Guin   +6 more
openalex   +1 more source

Matrix degradability controls multicellularity of 3D cell migration

Nature Communications, 2017
A major challenge in tissue engineering is the development of materials that can support angiogenesis, wherein endothelial cells from existing vasculature invade the surrounding matrix to form new vascular structures. To identify material properties that
B. Trappmann, Brendon M. Baker, William J. Polacheck, Colin K. Choi, J. Burdick, Christopher S. Chen   +5 more
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Shape of scaffold controlling the direction of cell migration

Biophysics and Physicobiology
Cell migration plays an important role in the development and maintenance of multicellular organisms. Factors that induce cell migration and mechanisms controlling their expression are important for determining the mechanisms of factor-induced cell ...
Hiroshi Sunami, Yusuke Shimizu, Hidehiro Kishimoto   +2 more
doaj   +1 more source

Role of glycosylation in hypoxia-driven cell migration and invasion

Cell Adhesion & Migration, 2019
Hypoxia, a common condition of the tumor microenvironment, induces changes in the proteome of cancer cells, mainly via HIF-1, a transcription factor conformed by a constitutively expressed β-subunit and an oxygen-regulated α-subunit.
Cecilia Arriagada, Patricio Silva, Vicente A. Torres   +2 more
doaj   +1 more source

KLF5 regulates epithelial-mesenchymal transition of liver cancer cells in the context of p53 loss through miR-192 targeting of ZEB2

Cell Adhesion & Migration, 2020
Krüppel-like factor 5 (KLF5) can both promote and suppress cell migration, but the underlying mechanisms have not been elucidated. In this study, we show that the function of KLF5 in epithelial-mesenchymal transition (EMT) and migration of liver cancer ...
Lan Sun, Xiaona Zhou, Yanmeng Li, Wei Chen, Shanna Wu, Bei Zhang, Jingyi Yao, Anjian Xu   +7 more
doaj   +1 more source

Directed cell migration towards softer environments

Nature Materials, 2022
A. Isomursu, Keun-Young Park, Jay Hou, Bo Cheng, Mathilde Mathieu, Ghaidan A Shamsan, Benjamin Fuller, Jesse Kasim, M. Mahmoodi, T. J. Lu, G. Genin, Feng Xu, Min Lin, M. Distefano, J. Ivaska, D. Odde   +15 more
semanticscholar   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Hyaluronan-CD44 interactions mediate contractility and migration in periodontal ligament cells

Cell Adhesion & Migration, 2019
The role of hyaluronan (HA) in periodontal healing has been speculated via its interaction with the CD44 receptor. While HA-CD44 interactions have previously been implicated in numerous cell types; effect and mechanism of exogenous HA on periodontal ...
Zeinab Al-Rekabi, Adriane M. Fura, Ilsa Juhlin, Alaa Yassin, Tracy E. Popowics, Nathan J. Sniadecki   +5 more
doaj   +1 more source