Results 111 to 120 of about 7,324,993 (258)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
India Migration Report 2024: Indians in Canada is one of the first volumes to comprehensively examine and analyse the different facets of Indian migration to Canada.
core +1 more source
The migration-remittances-development-nexus: ‘Mi casa con Remesas’ and transnational flows between Colombia and London [PDF]
, 2011 Zapata GP. The migration-remittances-development-nexus: ‘Mi casa con Remesas’ and transnational flows between Colombia and London. COMCAD Arbeitspapiere - Working Papers, 106.
Zapata, Gisela P.
core
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Migration transitions: a theoretical and empirical inquiry into the developmental drivers of international migration [PDF]
, 2010 This paper aims to advance a conceptual framework on the developmental drivers of international migration processes and to provide an empirical test drawing on the global migrant origin database.
de Haas, Hein
core +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Environmental Change and Migration: Governmental Compensation Policies to Natural Disasters Victims and Urbanization Process: A Case Study of Wildfires in Russian Federation in 2010 [PDF]
, 2011 Bobylev N. Environmental Change and Migration: Governmental Compensation Policies to Natural Disasters Victims and Urbanization Process: A Case Study of Wildfires in Russian Federation in 2010. COMCAD Arbeitspapiere - Working Papers, 100.
Bobylev, Nikolai
core