Results 101 to 110 of about 14,513,312 (335)
Cell Adhesion & Migration, 2021 We developed a computer-assisted platform using laser scanning confocal microscopy to 3D reconstruct in real-time interactions between metastatic breast cancer cells and human umbilical vein endothelial cells (HUVECs).
Deborah J. Wessels +13 more
doaj +1 more source
Fucosyltransferase 1 and 2 play pivotal roles in breast cancer cells. [PDF]
, 2019 FUT1 and FUT2 encode alpha 1, 2-fucosyltransferases which catalyze the addition of alpha 1, 2-linked fucose to glycans. Glycan products of FUT1 and FUT2, such as Globo H and Lewis Y, are highly expressed on malignant tissues, including breast cancer ...
Chang, Nai-Chuan +9 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Cancer Management and Research, 2020 Liu F, Chen Y, Chen B, Liu C, Xing J. Cancer Manag Res. 2019;11:10891–10900. At the authors request, the Editor-in-Chief and Publisher of Cancer Management and Research wish to retract the published article.
Liu F, Chen Y, Chen B, Liu C, Xing J
doaj
Cell Adhesion & Migration, 2019 The most prominent cancer-associated fibroblasts (CAFs) in tumor stroma is known to form a protective structure to support tumor growth. Anterior gradient-2 (AGR2), a tumor secretory protein is believed to play a pivotal role during tumor ...
Hitesh Bhagavanbhai Mangukiya +7 more
doaj +1 more source
The roles of serotonin in cell adhesion and migration, and cytoskeletal remodeling
Cell Adhesion & Migration, 2021 Serotonin is well known as a neurotransmitter. Its roles in neuronal processes such as learning, memory or cognition are well established, and also in disorders such as depression, schizophrenia, bipolar disorder, and dementia.
Joe Anand Kumar John Jayakumar +1 more
doaj +1 more source
Vimentin on the move: new developments in cell migration
F1000Research, 2018 The vimentin gene ( VIM) encodes one of the 71 human intermediate filament (IF) proteins, which are the building blocks of highly ordered, dynamic, and cell type-specific fiber networks.
Rachel A. Battaglia +3 more
semanticscholar +1 more source
Current Opinion in Genetics & Development, 1999 Recent genetic studies in Drosophila have identified signals that direct cell movement, mechanisms that transduce such signals within migrating cells and some of the molecular machinery underlying cell motility. Activation of the fibroblast growth factor receptor signaling pathway is required for migration of the cells of the developing respiratory ...
A, Forbes, R, Lehmann
openaire +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source