Results 101 to 110 of about 7,324,993 (258)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Migration as an Adaptation Strategy and Its Consequences on Coastal Society: Experience from Bangladesh [PDF]
, 2011 Mallick B. Migration as an Adaptation Strategy and Its Consequences on Coastal Society: Experience from Bangladesh. COMCAD Arbeitspapiere - Working Papers, 96.
Mallick, Bishawjit
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Recapitulation of molecular regulators of nuclear motion during cell migration
Cell Adhesion & Migration, 2019 Cell migration is a highly orchestrated cellular event that involves physical interactions of diverse subcellular components. The nucleus as the largest and stiffest organelle in the cell not only maintains genetic functionality, but also actively ...
Alexandra Sneider +3 more
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Control of Cell Shape, Neurite Outgrowth, and Migration by a Nogo-A/HSPG Interaction.
, 2017 Heparan sulfate proteoglycans (HSPGs) critically modulate adhesion-, growth-, and migration-related processes. Here, we show that the transmembrane protein, Nogo-A, inhibits neurite outgrowth and cell spreading in neurons and Nogo-A-responsive cell lines
Buffo, Annalisa +13 more
core +1 more source
Cell Adhesion & Migration, 2019 It is unclear if naïve T cells require dendritic cell ICAMs to proliferate inside lymph nodes. To check if and when CD4 lymphocytes use ICAMs on migratory DCs, wild-type and ICAM-1 and 2 double knock out bone marrow-derived DCs pulsed with saturating ...
Stav Kozlovski +4 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
The political economy of migration processes: An agenda for migration research and analysis [PDF]
, 2009 This working paper proposes the development of an approach to researching and analysing migration processes that combines a livelihoods aproach to exploring local-level migration dynamics with a relational political economy perspective that deepens ...
Collinson, Sarah
core +1 more source
Cell Adhesion & Migration, 2019 Mechanical stimuli influence various physiological processes in osteoblasts. We previously showed that mechano-growth factor (MGF), a splicing variant of insulin-like growth factor 1, is highly expressed in osteoblasts in response to mechanical stimuli ...
Qian Yi +6 more
doaj +1 more source