Results 31 to 40 of about 13,617,537 (304)
PLoS Computational Biology, 2020 Actin protrusion dynamics plays an important role in the regulation of three-dimensional (3D) cell migration. Cells form protrusions that adhere to the surrounding extracellular matrix (ECM), mechanically probe the ECM and contract in order to displace ...
Tommy Heck +5 more
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EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration.
Developmental Cell, 2018 Epithelial-mesenchymal transition (EMT) is strongly implicated in tumor cell invasion and metastasis. EMT is thought to be regulated primarily at the transcriptional level through the repressive activity of EMT transcription factors.
Nicole M. Aiello +11 more
semanticscholar +1 more source
WTAP regulates autophagy in colon cancer cells by inhibiting FLNA through N6-methyladenosine
Cell Adhesion & Migration, 2023 Our study investigated the role of WTAP in colon cancer. We employed experiments including m6A dot blot hybridization, methylated RNA immunoprecipitation, dual-luciferase, and RNA immunoprecipitation to investigate the regulatory mechanism of WTAP ...
Liang Huang +6 more
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Microtubules in cell migration
Essays in Biochemistry, 2019 Directed cell migration is critical for embryogenesis and organ development, wound healing and the immune response. Microtubules are dynamic polymers that control directional migration through a number of coordinated processes: microtubules are the ...
Clare L. Garcin, A. Straube
semanticscholar +1 more source
MST1/2 in inflammation and immunity
Cell Adhesion & Migration, 2023 The mammalian Sterile 20-like kinase 1/2 (MST1/2) belongs to the serine/threonine (GC) protein kinase superfamily. Collective studies confirm the vital role MST1/2 in inflammation and immunity.
Tongfen Li +7 more
doaj +1 more source
Frontiers in Immunology, 2015 Immunological memory is a key feature of adaptive immunity. It provides the organism with long-lived and robust protection against infection. In organ transplantation, memory T cells pose a significant threat by causing allograft rejection that is ...
Qianqian eZhang +2 more
doaj +1 more source
The functions of kinesin and kinesin-related proteins in eukaryotes
Cell Adhesion & Migration, 2020 Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks. Kinesins are found in all eukaryotic organisms and are essential to all eukaryotic
Iftikhar Ali, Wei-Cai Yang
doaj +1 more source
Cell Adhesion & Migration, 2023 The LMNA gene encoding lamin A/C is amplified in some clear cell renal cell carcinoma (ccRCC) samples. Our data showed that depletion of the tumor suppressor PBRM1 can upregulate lamin A/C levels, and lamin A/C could interact with PBRM1.
Hui Xin +8 more
doaj +1 more source
Alarmin‐induced cell migration [PDF]
European Journal of Immunology, 2013 Alarmins are endogenous, constitutively available, damage‐associated molecular patterns that upon release can mobilize and activate various leukocytes for the induction of innate and adaptive immune responses. For our immune system to function appropriately, it relies on navigating various leukocytes to distinct places at the right time.
De, Yang +4 more
openaire +2 more sources