Results 31 to 40 of about 12,335,534 (353)
WTAP regulates autophagy in colon cancer cells by inhibiting FLNA through N6-methyladenosine
Cell Adhesion & Migration, 2023 Our study investigated the role of WTAP in colon cancer. We employed experiments including m6A dot blot hybridization, methylated RNA immunoprecipitation, dual-luciferase, and RNA immunoprecipitation to investigate the regulatory mechanism of WTAP ...
Liang Huang +6 more
doaj +1 more source
Frontiers in Immunology, 2015 Immunological memory is a key feature of adaptive immunity. It provides the organism with long-lived and robust protection against infection. In organ transplantation, memory T cells pose a significant threat by causing allograft rejection that is ...
Qianqian eZhang +2 more
doaj +1 more source
MST1/2 in inflammation and immunity
Cell Adhesion & Migration, 2023 The mammalian Sterile 20-like kinase 1/2 (MST1/2) belongs to the serine/threonine (GC) protein kinase superfamily. Collective studies confirm the vital role MST1/2 in inflammation and immunity.
Tongfen Li +7 more
doaj +1 more source
Alarmin‐induced cell migration [PDF]
European Journal of Immunology, 2013 Alarmins are endogenous, constitutively available, damage‐associated molecular patterns that upon release can mobilize and activate various leukocytes for the induction of innate and adaptive immune responses. For our immune system to function appropriately, it relies on navigating various leukocytes to distinct places at the right time.
De, Yang +4 more
openaire +2 more sources
Actin dynamics in cell migration
Essays in Biochemistry, 2019 Cell migration is an essential process, both in unicellular organisms such as amoeba and as individual or collective motility in highly developed multicellular organisms like mammals.
M. Schaks, Grégory Giannone, K. Rottner
semanticscholar +1 more source
The functions of kinesin and kinesin-related proteins in eukaryotes
Cell Adhesion & Migration, 2020 Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks. Kinesins are found in all eukaryotic organisms and are essential to all eukaryotic
Iftikhar Ali, Wei-Cai Yang
doaj +1 more source
Cell Adhesion & Migration, 2023 The LMNA gene encoding lamin A/C is amplified in some clear cell renal cell carcinoma (ccRCC) samples. Our data showed that depletion of the tumor suppressor PBRM1 can upregulate lamin A/C levels, and lamin A/C could interact with PBRM1.
Hui Xin +8 more
doaj +1 more source
Tissue stiffening coordinates morphogenesis by triggering collective cell migration in vivo
Nature, 2018 Collective cell migration is essential for morphogenesis, tissue remodelling and cancer invasion. In vivo, groups of cells move in an orchestrated way through tissues.
E. Barriga +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Cell Adhesion & Migration, 2020 To elucidate the underlying mechanism of secretory leukocyte protease inhibitor (SLPI)-induced cell migration, we compared SLPI-deleted human gingival carcinoma Ca9-22 (ΔSLPI) cells and original (wild-type: wt) Ca9-22 cells using several microscopic ...
Yusuke Mizutani +6 more
doaj +1 more source