Results 41 to 50 of about 1,804,531 (255)

WTAP regulates autophagy in colon cancer cells by inhibiting FLNA through N6-methyladenosine

open access: yesCell Adhesion & Migration, 2023
Our study investigated the role of WTAP in colon cancer. We employed experiments including m6A dot blot hybridization, methylated RNA immunoprecipitation, dual-luciferase, and RNA immunoprecipitation to investigate the regulatory mechanism of WTAP ...
Liang Huang   +6 more
doaj   +1 more source

MST1/2 in inflammation and immunity

open access: yesCell Adhesion & Migration, 2023
The mammalian Sterile 20-like kinase 1/2 (MST1/2) belongs to the serine/threonine (GC) protein kinase superfamily. Collective studies confirm the vital role MST1/2 in inflammation and immunity.
Tongfen Li   +7 more
doaj   +1 more source

The functions of kinesin and kinesin-related proteins in eukaryotes

open access: yesCell Adhesion & Migration, 2020
Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks. Kinesins are found in all eukaryotic organisms and are essential to all eukaryotic
Iftikhar Ali, Wei-Cai Yang
doaj   +1 more source

Knockdown of LMNA inhibits Akt/β-catenin-mediated cell invasion and migration in clear cell renal cell carcinoma cells

open access: yesCell Adhesion & Migration, 2023
The LMNA gene encoding lamin A/C is amplified in some clear cell renal cell carcinoma (ccRCC) samples. Our data showed that depletion of the tumor suppressor PBRM1 can upregulate lamin A/C levels, and lamin A/C could interact with PBRM1.
Hui Xin   +8 more
doaj   +1 more source

SLPI facilitates cell migration by regulating lamellipodia/ruffles and desmosomes, in which Galectin4 plays an important role

open access: yesCell Adhesion & Migration, 2020
To elucidate the underlying mechanism of secretory leukocyte protease inhibitor (SLPI)-induced cell migration, we compared SLPI-deleted human gingival carcinoma Ca9-22 (ΔSLPI) cells and original (wild-type: wt) Ca9-22 cells using several microscopic ...
Yusuke Mizutani   +6 more
doaj   +1 more source

A myristoylated alanine-rich C-kinase substrate (MARCKS) inhibitor peptide attenuates neutrophil outside-in β2-integrin activation and signaling

open access: yesCell Adhesion & Migration, 2023
MARCKS is an actin and PIP2-binding protein that plays an essential role in neutrophil migration and adhesion; however, the molecular details regarding MARCKS function in these processes remains unclear. Neutrophil adhesion and migration also require the
Haleigh Conley   +4 more
doaj   +1 more source

Cell migration on material-driven fibronectin microenvironments [PDF]

open access: yes, 2017
Cell migration is a fundamental process involved in a wide range of biological phenomena. However, how the underlying mechanisms that control migration are orchestrated is not fully understood.
Cantini, M.   +4 more
core   +1 more source

Cell Migration Research Based on Organ-on-Chip-Related Approaches

open access: yesMicromachines, 2017
Microfluidic devices have been widely used for cell migration research over the last two decades, owing to their attractive features in cellular microenvironment control and quantitative single-cell migration analysis.
Xiaoou Ren, David Levin, Francis Lin
doaj   +1 more source

Inhibition of DDR1 reduces invasive features of human A375 melanoma, HT29 colon carcinoma and SK-HEP hepatoma cells

open access: yesCell Adhesion & Migration, 2020
DDR1 is a receptor tyrosine kinases for collagen and an adverse prognostic factor in primary and metastatic tumors.Despite this, DDR1 signaling and its functional consequences in tumor development remain unclear.
Irene Romayor   +2 more
doaj   +1 more source

Microtubules in cell migration [PDF]

open access: yesEssays in Biochemistry, 2019
AbstractDirected cell migration is critical for embryogenesis and organ development, wound healing and the immune response. Microtubules are dynamic polymers that control directional migration through a number of coordinated processes: microtubules are the tracks for long-distance intracellular transport, crucial for delivery of new membrane components
Clare Garcin, Anne Straube
openaire   +2 more sources

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