Cell migration directionality and speed are independently regulated by RasG and Gβ in Dictyostelium cells in electrotaxis. [PDF]
, 2019 Motile cells manifest increased migration speed and directionality in gradients of stimuli, including chemoattractants, electrical potential and substratum stiffness.
Devreotes, Peter N +6 more
core
Directing cell migration and organization via nanocrater-patterned cell-repellent interfaces. [PDF]
, 2015 Although adhesive interactions between cells and nanostructured interfaces have been studied extensively, there is a paucity of data on how nanostructured interfaces repel cells by directing cell migration and cell-colony organization.
Grigoropoulos, Costas P. +5 more
core +2 more sources
Cell Adhesion & Migration, 2021 Neuroblastoma is a highly metastatic tumor that emerges from neural crest cell progenitors. Focal Adhesion Kinase (FAK) is a regulator of cell migration that binds to the receptor Neogenin-1 and is upregulated in neuroblastoma.
Andrea A. Villanueva +14 more
doaj +1 more source
Cell Adhesion & Migration, 2019 The natural flavonoid quercetin has antioxidant, anti-inflammatory, and anticancer effects. We investigated the effect of quercetin on lipopolysaccharide (LPS)-induced macrophage migration.
Shuna Cui +5 more
doaj +1 more source
Cell Adhesion & Migration, 2021 MAGI1 is an intracellular adaptor protein that stabilizes cell junctions and regulates epithelial and endothelial integrity. Here, we report that that in endothelial cells MAGI1 colocalizes with paxillin, β3-integrin, talin 1, tensin 3 and α-4-actinin at
Begoña Alday-Parejo +7 more
doaj +1 more source
Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling. [PDF]
, 2015 In glioblastoma (GBM), the EGF receptor (EGFR) and Src family kinases (SFKs) contribute to an aggressive phenotype. EGFR may be targeted therapeutically; however, resistance to EGFR-targeting drugs such as Erlotinib and Gefitinib develops quickly.
Cavenee, WK +5 more
core
Identification of non-canonical NF-κB signaling as a critical mediator of Smac mimetic-stimulated migration and invasion of glioblastoma cells [PDF]
, 2013 As inhibitor of apoptosis (IAP) proteins can regulate additional signaling pathways beyond apoptosis, we investigated the effect of the second mitochondrial activator of caspases (Smac) mimetic BV6, which antagonizes IAP proteins, on non-apoptotic ...
Eckhardt, Ines +4 more
core +2 more sources
Atypical PKCs activate Vimentin to facilitate prostate cancer cell motility and invasion
Cell Adhesion & Migration, 2021 Atypical protein kinase C (aPKC) are involved in progression of many human cancers. Vimentin is expressed during epithelial to mesenchymal transition (EMT). Molecular dynamics of Vimentin intermediate filaments (VIFs) play a key role in metastasis.
Wishrawana S. Ratnayake +5 more
doaj +1 more source
Migration and proliferation dichotomy in tumor cell invasion [PDF]
, 2006 We propose a two-component reaction-transport model for the migration-proliferation dichotomy in the spreading of tumor cells. By using a continuous time random walk (CTRW) we formulate a system of the balance equations for the cancer cells of two ...
A. Iomin +5 more
core +1 more source
α– Linolenic acid modulates phagocytosis and endosomal pathways of extracellular Tau in microglia
Cell Adhesion & Migration, 2021 Microglia, the resident immune cells, were found to be activated to inflammatory phenotype in Alzheimer’s disease (AD). The extracellular burden of amyloid-β plaques and Tau seed fabricate the activation of microglia.
Smita Eknath Desale +1 more
doaj +1 more source