Results 31 to 40 of about 537,274 (296)

Mechanics of motility initiation and motility arrest in crawling cells

open access: yes, 2015
Motility initiation in crawling cells requires transformation of a symmetric state into a polarized state. In contrast, motility arrest is associated with re-symmetrization of the internal configuration of a cell.
Putelat, Thibaut   +2 more
core   +1 more source

Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer. [PDF]

open access: yes, 2017
Tumors adapt to an unfavorable microenvironment by controlling the balance between cell proliferation and cell motility, but the regulators of this process are largely unknown.
Ashani T. Weeraratna   +17 more
core   +2 more sources

Exopolysaccharide-independent social motility of Myxococcus xanthus. [PDF]

open access: yesPLoS ONE, 2011
Social motility (S motility), the coordinated movement of large cell groups on agar surfaces, of Myxococcus xanthus requires type IV pili (TFP) and exopolysaccharides (EPS).
Wei Hu   +6 more
doaj   +1 more source

Modelling biological invasions: individual to population scales at interfaces [PDF]

open access: yes, 2013
Extracting the population level behaviour of biological systems from that of the individual is critical in understanding dynamics across multiple scales and thus has been the subject of numerous investigations.
Belmonte-Beitia, J   +4 more
core   +2 more sources

Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions

open access: yesNature Communications, 2017
Actin and microtubules play important roles in Golgi structure and function but how they are connected is poorly understood. Here the authors show that KIF20A is involved in the fission process and, in association with Myosin II, serves to anchor RAB6 on
Stéphanie Miserey-Lenkei   +12 more
doaj   +1 more source

A cell behavior screen: identification, sorting, and enrichment of cells based on motility

open access: yesBMC Cell Biology, 2005
Background Identifying and isolating cells with specific behavioral characteristics will facilitate the understanding of the molecular basis regulating these behaviors.
Chen Kwan Y   +2 more
doaj   +1 more source

Identification of a third myosin-5a-melanophilin interaction that mediates the association of myosin-5a with melanosomes

open access: yeseLife
Transport and localization of melanosome at the periphery region of melanocyte are depended on myosin-5a (Myo5a), which associates with melanosome by interacting with its adaptor protein melanophilin (Mlph).
Jiabin Pan   +7 more
doaj   +1 more source

Inhibition of SIRT2 Potentiates the Anti-motility Activity of Taxanes: Implications for Antineoplastic Combination Therapies

open access: yesNeoplasia: An International Journal for Oncology Research, 2012
Taxanes are potent inhibitors of cell motility, a property implicated in their antiangiogenic and antimetastatic activity and unrelated to their antiproliferative effect. The molecular mechanism of this anti-motility activity is poorly understood.
Katiuscia Bonezzi   +10 more
doaj   +1 more source

Active Gel Model of Amoeboid Cell Motility

open access: yes, 2013
We develop a model of amoeboid cell motility based on active gel theory. Modeling the motile apparatus of a eukaryotic cell as a confined layer of finite length of poroelastic active gel permeated by a solvent, we first show that, due to active stress ...
Callan-Jones, A. C., Voituriez, R.
core   +1 more source

Collective and single cell behavior in epithelial contact inhibition [PDF]

open access: yes, 2011
Control of cell proliferation is a fundamental aspect of tissue physiology central to morphogenesis, wound healing and cancer. Although many of the molecular genetic factors are now known, the system level regulation of growth is still poorly understood.
A. Puliafito   +42 more
core   +4 more sources

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