Results 11 to 20 of about 347,216 (308)

Targeted Next-Generation Sequencing Reveals Mutations in Non-coding Regions and Potential Regulatory Sequences of Calpain-3 Gene in Polish Limb–Girdle Muscular Dystrophy Patients

Frontiers in Neuroscience, 2021
Limb–girdle muscular dystrophy type R1 (LGMDR1) is caused by mutations in CAPN3 and is the most common type of recessive LGMD. Even with the use of whole-exome sequencing (WES), only one mutant allele of CAPN3 is found in a significant number of LGMDR ...
Anna Macias, Jakub Piotr Fichna, Malgorzata Topolewska, Maria J. Rȩdowicz, Anna M. Kaminska, Anna Kostera-Pruszczyk   +5 more
doaj   +1 more source

VASP-mediated actin dynamics activate and recruit a filopodia myosin

eLife, 2021
Filopodia are thin, actin-based structures that cells use to interact with their environments. Filopodia initiation requires a suite of conserved proteins but the mechanism remains poorly understood. The actin polymerase VASP and a MyTH-FERM (MF) myosin,
Ashley L Arthur, Amy Crawford, Anne Houdusse, Margaret A Titus   +3 more
doaj   +1 more source

Cell Motility [PDF]

Journal of Cell Science, 1986
Approximately 20 years have passed since the first isolation of tubulin, dynein and non-muscle actomyosin. During this period actomyosin, microtubule-dynein or microtubules plus other ATPases (kinesin) have been implicated in almost all cellular motile phenomena.
openaire   +2 more sources

Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour [PDF]

, 2011
The mechanism of eukaryotic chemotaxis remains unclear despite intensive study. The most frequently described mechanism acts through attractants causing actin polymerization, in turn leading to pseudopod formation and cell movement.
Haastert, Peter J.M. van,, Peter J M van Haastert, van Haastert, Peter J. M., van Haastert, Peter J.M., Matthew P. Neilson, Douwe M Veltman, Webb, Steven D., Insall, Robert H., Webb, Steven D.,, Neilson, Matthew P.,, Neilson, Matthew P., Matthew P Neilson, Douwe M. Veltman, Peter J. M. van Haastert, Insall, Robert H.,, Steven D Webb, Webb, Steven, Robert H Insall, John A. Mackenzie, Mackenzie, John A.,, John A Mackenzie, Veltman, Douwe M.,, Mackenzie, John A., Veltmahn, Douwe M., Veltman, Douwe M., Steven D. Webb, Robert H. Insall   +26 more
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Impact of Microscopic Motility on the Swimming Behavior of Parasites : Straighter Trypanosomes are More Directional [PDF]

, 2011
Microorganisms, particularly parasites, have developed sophisticated swimming mechanisms to cope with a varied range of environments. African Trypanosomes, causative agents of fatal illness in humans and animals, use an insect vector (the Tsetse fly) to ...
Nagler, J., Engstler, M., Heddergott, Niko, Sravanti Uppaluri, Herminghaus, Stephan, Heddergot, Niko, Pfohl, T., Heddergot, N., Stellamanns, E., Stephan Herminghaus, Pfohl, Thomas, Uppaluri, S., Herminghaus, S., Uppaluri, Sravanti, Markus Engstler, Engstler, Markus, Eric Stellamanns, Stellamanns, Eric, Jan Nagler, Niko Heddergott, Nagler, Jan, Thomas Pfohl   +21 more
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The ErbB2 receptor and breast carcinoma cell migration : memo is a novel mediator of cell motility [PDF]

, 2003
The ErbB family of receptor tyrosine kinases play important role in normal physiological processes occurring during development; moreover, their deregulated expression has been implicated in human cancer. Cancer patients, whose tumors have alterations in
Marone, Romina
core   +1 more source

Caffeine Inhibits EGF-Stimulated Trophoblast Cell Motility through the Inhibition of mTORC2 and Akt. [PDF]

, 2012
Impaired trophoblast invasion is associated with pregnancy disorders such as early pregnancy loss and preeclampsia. There is evidence to suggest that the consumption of caffeine during pregnancy may increase the risk of pregnancy loss; however, little is
Lumicisi, B, Cartwright, JE, Whitley, GS, Grant, I, Wallace, AE   +4 more
core   +1 more source

On the mechanical interplay between intra- and inter-synchronization during collective cell migration : a numerical investigation [PDF]

, 2013
Collective cell migration is a fundamental process that takes place during several biological phenomena such as embryogenesis, immunity response, and tumorogenesis, but the mechanisms that regulate it are still unclear.
ALLENA, Rachele, Sharpe, J., AUBRY, Denis, SHARPE, James   +3 more
core   +1 more source

Microtubules in 3D cell motility [PDF]

, 2017
Three-dimensional (3D) cell motility underlies essential processes, such as embryonic development, tissue repair and immune surveillance, and is involved in cancer progression. Although the cytoskeleton is a well-studied regulator of cell migration, most
Sub Cell Biology, Celbiologie, Anna Akhmanova, Bouchet, Benjamin P, Benjamin P. Bouchet, Akhmanova, Anna   +5 more
core   +1 more source

Bacterial Motility in Biofilm Under Shear Flow

Chemical Engineering Transactions, 2022
A key role in bacteria surfaces contamination and biofilm development is played by cell motility and adhesion, that can be heavily dependent on flow conditions.
Daniele Marra, Federica Recupido, Giuseppe Toscano, Sergio Caserta   +3 more
doaj   +1 more source