Results 91 to 100 of about 4,939,783 (282)

A mammalian model reveals inorganic polyphosphate channeling into the nucleolus and induction of a hyper-condensate state

Cell Reports: Methods
Summary: Inorganic polyphosphate (polyP) is a ubiquitous polymer that controls fundamental processes. To overcome the absence of a genetically tractable mammalian model, we developed an inducible mammalian cell line expressing Escherichia coli ...
Filipy Borghi, Cristina Azevedo, Errin Johnson, Jemima J. Burden, Adolfo Saiardi   +4 more
doaj   +1 more source

SUMO regulates p21Cip1 intracellular distribution and with p21Cip1 facilitates multiprotein complex formation in the nucleolus upon DNA damage.

PLoS ONE, 2017
We previously showed that p21Cip1 transits through the nucleolus on its way from the nucleus to the cytoplasm and that DNA damage inhibits this transit and induces the formation of p21Cip1-containing intranucleolar bodies (INoBs).
Sonia Brun, Neus Abella, Maria T Berciano, Olga Tapia, Montserrat Jaumot, Raimundo Freire, Miguel Lafarga, Neus Agell   +7 more
doaj   +1 more source

A geometric chracterization of the nucleolus of the assignment game [PDF]

core, assignment games, nucleolus, cooperative games ...
Francesc Llerena, Marina Nunez, Carles Rafels   +2 more
core  

Comparative analysis of TP53 gene in Tupaia belangeri subspecies (Tupaia belangeri yaoshanensis vs. Tupaia belangeri chinensis) and identification of mutations in spontaneous tumor cases

Animal Models and Experimental Medicine, EarlyView.
This study provides the first evidence of natural TP53 variation between tree shrew subspecies and identifies somatic TP53 mutations in spontaneous tree shrew sarcomas. The high structural and functional conservation of tree shrew p53 with humans supports its utility as a relevant model for TP53‐related cancer research.
Yingying Cao, Haibo Tang, Liang Liang, Jing Leng, Weijian Huang   +4 more
wiley   +1 more source

The HIV Tat protein affects processing of ribosomal RNA precursor

BMC Cell Biology, 2008
Background Inside the cell, the HIV Tat protein is mainly found in the nucleus and nucleolus. The nucleolus, the site of ribosome biogenesis, is a highly organized, non-membrane-bound sub-compartment where proteins with a high affinity for nucleolar ...
Bellenchi Gian, Troiano Maria, Ponti Donatella, Battaglia Piero A, Gigliani Franca   +4 more
doaj   +1 more source

Rna Buffering Fluorogenic Probe for Nucleolar Morphology Stable Imaging And Nucleolar Stress‐Generating Agents Screening

Advanced Science
In the realm of cell research, membraneless organelles have become a subject of increasing interest. However, their ever‐changing and amorphous morphological characteristics have long presented a formidable challenge when it comes to studying their ...
Wenchao Jiang, Qinglong Qiao, Jie Chen, Pengjun Bao, Yi Tao, Yinchan Zhang, Zhaochao Xu   +6 more
doaj   +1 more source

A nucleolar localizing Rev binding element inhibits HIV replication

AIDS Research and Therapy, 2006
The Rev protein of the human immunodeficiency virus (HIV) facilitates the nuclear export of intron containing viral mRNAs allowing formation of infectious virions. Rev traffics through the nucleolus and shuttles between the nucleus and cytoplasm.
Bozzoni Irene, De Angelis Fernanda G, Michienzi Alessandro, Rossi John J   +3 more
doaj   +1 more source

Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery [PDF]

, 2014
Copyright @ 2014 Booth et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.When the nucleolus ...
Elizabeth Petfalski, Vagnarelli, Paola, Ponting, Christopher, David Tollervey, Earnshaw, William C, Imamoto, N, Petfalski, Elizabeth, Sanchez-Pulido, Luis, Giulia Vargiu, Takagi, M, Booth, DG, Luis Sanchez-Pulido, Tollervey, David, Ponting, Chris P, Petfalski, E, Ponting, CP, Vargiu, Giulia, Tollervey, D, Naoko Imamoto, Ponting, Chris P.; id_orcid, Earnshaw, William C., Daniel G Booth, Vagnarelli, P, Kumiko Samejima, Imamoto, Naoko, Booth, Daniel G, William C Earnshaw, Masatoshi Takagi, Samejima, Kumiko, Sanchez-Pulido, L, Vargiu, G, Booth, Daniel G., Chris P Ponting, Paola Vagnarelli, Takagi, Masatoshi, Samejima, K, Earnshaw, WC   +36 more
core   +1 more source

Gonadal development in scorpion mud‐turtles, Kinosternon scorpioides, in a controlled environment

The Anatomical Record, EarlyView.
Stage 20 was identified as the critical point for gonadal differentiation in Kinosternon scorpioides, providing key insights into sex determination. These findings enhance conservation strategies by supporting reproductive management and population viability in both in situ and ex situ programs. Abstract Research on gonadal development including sexual
Brenda Braga, Verônica Oliveira‐Bahia, Maria Auxiliadora Ferreira, José Ribamar Felipe Marques, Diva Araújo Guimarães   +4 more
wiley   +1 more source

Unraveling ovarian histology: The key morphological aspects that spur the development of the Fossa ovarii in equine

The Anatomical Record, EarlyView.
Abstract The equine ovary exhibits unique structural and developmental features that distinguish it from those of other domestic species, including the presence of an ovulation fossa and an inversion of cortical and medullary layers. This study aimed to investigate the morphostructural development of the equine fetal ovary, with particular emphasis on ...
Laura Ver Goltz, Silvio Pires Gomes, Bruno Cesar Schimming, Fabio Cesar Magioli Abdala, Maria Angélica Miglino, Tais Harumi de Castro Sasahara   +5 more
wiley   +1 more source