Results 71 to 80 of about 52,621 (199)

A nonribosomal landscape in the nucleolus revealed by the stem cell protein nucleostemin

, 2009
Nucleostemin is a p53-interactive cell cycle progression factor that shuttles between the nucleolus and nucleoplasm, but it has no known involvement in ribosome synthesis.
Bazett-Jones, David P., Pederson, Thoru, Politz, Joan C. Ritland, Trask, Ian, Polena, Ilvin   +4 more
core   +1 more source

Nucleolar origins: challenging perspectives on evolution and function

Open Biology
The nucleolus, once considered a mere ‘ribosome factory’, is now recognized as a dynamic hub influencing nearly every aspect of cellular life, from genome organization to stress response and ageing.
Israel Muñoz-Velasco, Ana Karen Herrera-Escamilla, Alberto Vázquez-Salazar   +2 more
doaj   +1 more source

The transcription factor EGR1 localizes to the nucleolus and is linked to suppression of ribosomal precursor synthesis.

PLoS ONE, 2014
EGR1 is an immediate early gene with a wide range of activities as transcription factor, spanning from regulation of cell growth to differentiation. Numerous studies show that EGR1 either promotes the proliferation of stimulated cells or suppresses the ...
Donatella Ponti, Gian Carlo Bellenchi, Rosa Puca, Daniela Bastianelli, Marella Maroder, Giuseppe Ragona, Pascal Roussel, Marc Thiry, Dan Mercola, Antonella Calogero   +9 more
doaj   +1 more source

SUMO regulates p21Cip1 intracellular distribution and with p21Cip1 facilitates multiprotein complex formation in the nucleolus upon DNA damage.

PLoS ONE, 2017
We previously showed that p21Cip1 transits through the nucleolus on its way from the nucleus to the cytoplasm and that DNA damage inhibits this transit and induces the formation of p21Cip1-containing intranucleolar bodies (INoBs).
Sonia Brun, Neus Abella, Maria T Berciano, Olga Tapia, Montserrat Jaumot, Raimundo Freire, Miguel Lafarga, Neus Agell   +7 more
doaj   +1 more source

The HIV Tat protein affects processing of ribosomal RNA precursor

BMC Cell Biology, 2008
Background Inside the cell, the HIV Tat protein is mainly found in the nucleus and nucleolus. The nucleolus, the site of ribosome biogenesis, is a highly organized, non-membrane-bound sub-compartment where proteins with a high affinity for nucleolar ...
Bellenchi Gian, Troiano Maria, Ponti Donatella, Battaglia Piero A, Gigliani Franca   +4 more
doaj   +1 more source

Meiotic nuclear divisions in budding yeast require PP2ACdc55-mediated antagonism of Net1 phosphorylation by Cdk [PDF]

, 2011
During meiosis, one round of deoxyribonucleic acid replication is followed by two rounds of nuclear division. In Saccharomyces cerevisiae, activation of the Cdc14 early anaphase release (FEAR) network is required for exit from meiosis I but does not lead
Sourav Sarkar, Millar, Jonathan B.A., Kerr, Gary W., Tibbles, Katherine L., Prakash Arumugam, Kerr, Gary, Gary W. Kerr, Sarkar, Sourav, Millar, Jonathan B. A., Katherine L. Tibbles, Jonathan B.A. Millar, Arumugam, Prakash, Mark Petronczki, Petronczki, Mark   +13 more
core   +1 more source

The Nucleolus and Nucleolar Proteins of Dictyostelium

, 2012
Dictyostelium is a model eukaryote for the study of a multitude of fundamental cellular processes as well as several human diseases. Despite its extensive study relatively little is known about its nucleolus.
Catalano, Andrew Joseph
core   +1 more source

Rna Buffering Fluorogenic Probe for Nucleolar Morphology Stable Imaging And Nucleolar Stress‐Generating Agents Screening

Advanced Science
In the realm of cell research, membraneless organelles have become a subject of increasing interest. However, their ever‐changing and amorphous morphological characteristics have long presented a formidable challenge when it comes to studying their ...
Wenchao Jiang, Qinglong Qiao, Jie Chen, Pengjun Bao, Yi Tao, Yinchan Zhang, Zhaochao Xu   +6 more
doaj   +1 more source

A nucleolar localizing Rev binding element inhibits HIV replication

AIDS Research and Therapy, 2006
The Rev protein of the human immunodeficiency virus (HIV) facilitates the nuclear export of intron containing viral mRNAs allowing formation of infectious virions. Rev traffics through the nucleolus and shuttles between the nucleus and cytoplasm.
Bozzoni Irene, De Angelis Fernanda G, Michienzi Alessandro, Rossi John J   +3 more
doaj   +1 more source

The functional organization of the nucleolus in proliferating plant cells.

European journal of histochemistry : EJH, 2000
The nucleolus is a prominent nuclear organelle which morphologically expresses all functional steps necessary for the synthesis of ribosomes, from transcription of rRNA genes to the assembly and maturation of preribosomal particles and their transport to the cytoplasm. Structurally, the nucleolus contains some basic components common to practically all
Medina, F. Javier, Cerdido, Antonio, Cárcer, Guillermo de   +2 more
openaire   +2 more sources