Results 61 to 70 of about 52,621 (199)

The Nucleolus

, 2023
The nucleolus is a prominent structure within the interphase nucleus that is visible by conventional light microscopy. Nucleoli are highly dynamic, polymorphic structures.
Hutten, Saskia, Ly, Tony, Nicolas, Armel, Lamond, Angus I.; id_orcid   +3 more
core   +1 more source

Myeloma cells contain high levels of inorganic polyphosphate which is associated with nucleolar transcription

Haematologica, 2012
Background In hematology there has recently been increasing interest in inorganic polyphosphate. This polymer accumulates in platelet granules and its functions include modulating various stages of blood coagulation, inducing angiogenesis, and provoking ...
Maria D. Jimenez-Nuñez, David Moreno-Sanchez, Laura Hernandez-Ruiz, Alicia Benítez-Rondán, Ana Ramos-Amaya, Beatriz Rodríguez-Bayona, Francisco Medina, José Antonio Brieva, Felix A. Ruiz   +8 more
doaj   +1 more source

MBoC | ARTICLE Environmental cues induce a long noncoding RNA–dependent remodeling of the nucleolus

, 2013
The nucleolus is a plurifunctional organelle in which structure and function are intimately linked. Its structural plasticity has long been appreciated, particularly in response to transcriptional inhibition and other cellular stresses, although the ...
Jacob, Mathieu D, Laura Trinkle-mulcahy, Trinkle-Mulcahy, Laura, Uniacke, James, Mathieu D. Jacob, Timothy E. Audas, James Uniacke, Audas, Timothy E, Stephen Lee, Lee, Stephen   +9 more
core   +1 more source

RNA Pol-II transcripts in nucleolar associated domains of cancer cell nucleoli

Nucleus
We performed a comparative study of the non-ribosomal gene content of nucleoli from seven cancer cell lines, using identical methods of purification and analysis.
Soumya Roy Chowdhury, Arunima Shilpi, Gary Felsenfeld   +2 more
doaj   +1 more source

Effect of short- and long-lasting chilling on pre-rRNA synthesis and transport in root meristematic cells of three soybean cultivars

Acta Societatis Botanicorum Poloniae, 2011
Autoradiographic studies of 3H-uridine incorporation (20-min incubation) and dynamics of radioactive particle translocation from nucleolus into cytoplasm (following 80-min postincubation in non-radioactive medium) in root meristematic cells of soybean ...
Dariusz Stępiński
doaj   +1 more source

Quantitative nucleolar proteomics reveals nuclear re-organization during stress- induced senescence in mouse fibroblast

BMC Cell Biology, 2011
Background Nucleolus is the most prominent mammalian organelle within the nucleus which is also the site for ribosomal biogenesis. There have been many reports indicating the involvement of nucleolus in the process of aging.
Zhou Zhongjun, Liu Baohua, kar Bishnupriya, Lam Yun W   +3 more
doaj   +1 more source

Essential roles of the nucleolus during early embryonic development: a regulatory hub for chromatin organization

Open Biology
The nucleolus is the most prominent liquid droplet-like membrane-less organelle in mammalian cells. Unlike the nucleolus in terminally differentiated somatic cells, those in totipotent cells, such as murine zygotes or two-cell embryos, have a unique ...
Bo Fu, Hong Ma, Di Liu
doaj   +1 more source

Influenza A H3N2 subtype virus NS1 protein targets into the nucleus and binds primarily via its C-terminal NLS2/NoLS to nucleolin and fibrillarin

Virology Journal, 2012
Background Influenza A virus non-structural protein 1 (NS1) is a virulence factor, which is targeted into the cell cytoplasm, nucleus and nucleolus. NS1 is a multi-functional protein that inhibits host cell pre-mRNA processing and counteracts host cell ...
Melén Krister, Tynell Janne, Fagerlund Riku, Roussel Pascal, Hernandez-Verdun Danièle, Julkunen Ilkka   +5 more
doaj   +1 more source

Localisation of the Ki-67 antigen within the nucleolus: Evidence for a fibrillarin-deficient region of the dense fibrillar component

, 1996
The Ki-67 antigen is detected in proliferating cells in all phases of the cell division cycle. Throughout most of interphase, the Ki-67 antigen is localised within the nucleolus.
Kill, IR
core  

Emerging roles for the nucleolus in development and stem cells

Development
ABSTRACT The nucleolus is a membrane-less subnuclear compartment known for its role in ribosome biogenesis. However, emerging evidence suggests that nucleolar function extends beyond ribosome production and is particularly important during mammalian development.
Bryony J. Leeke, Imke Staffhorst, Michelle Percharde   +2 more
openaire   +2 more sources