Results 51 to 60 of about 52,621 (199)

Physicochemical Properties of Nucleoli in Live Cells Analyzed by Label-Free Optical Diffraction Tomography

Cells, 2019
The cell nucleus is three-dimensionally and dynamically organized by nuclear components with high molecular density, such as chromatin and nuclear bodies. The structure and functions of these components are represented by the diffusion and interaction of
Tae-Keun Kim, Byong-Wook Lee, Fumihiko Fujii, Jun Ki Kim, Chan-Gi Pack   +4 more
doaj   +1 more source

Targeted knock-down of miR21 primary transcripts using snoMEN vectors induces apoptosis in human cancer cell lines [PDF]

, 2015
We have previously reported an antisense technology, ‘snoMEN vectors’, for targeted knock-down of protein coding mRNAs using human snoRNAs manipulated to contain short regions of sequence complementarity with the mRNA target. Here we characterise the use
Bensaddek, Dalila, Motoharu Ono, Lamond Angus I., Ono Motoharu, Fabio Avolio (259547), Afzal, Vackar, Vackar Afzal, Dalila Bensaddek, Vackar Afzal (800170), Avolio Fabio, Lamond, Angus I.; id_orcid, Motoharu Ono (259551), Afzal Vackar, Kayo Yamada, Bensaddek Dalila, Angus I Lamond, Avolio, Fabio, Yamada Kayo, Ono, Motoharu, Kayo Yamada (407407), Fabio Avolio, Angus I. Lamond (13065), Ono, Kayo, Dalila Bensaddek (800171)   +23 more
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The nucleolus [PDF]

, 2009
The nucleolus is the most prominent subnuclear compartment in eukaryotic cells. It has a central function in the biogenesis of ribosomal subunits, but the past decade has revealed that a variety of additional non-ribosomal ribonucleoprotein (RNP ...
Jellbauer, Stephan
core  

Assembly and disassembly of the nucleolus during the cell cycle [PDF]

Nucleus, 2011
The nucleolus is a large nuclear domain in which transcription, maturation and assembly of ribosomes take place. In higher eukaryotes, nucleolar organization in three sub-domains reflects the compartmentation of the machineries related to active or inactive transcription of the ribosomal DNA, ribosomal RNA processing and assembly with ribosomal ...
openaire   +3 more sources

Cell cycle switch to endocycle: The nucleolus lends a hand [PDF]

Cell Cycle, 2008
The bHLH transcription factor Hand1 is essential for placentation and cardiac morphogenesis but how its developmental activity is regulated is largely unknown. We recently showed that Hand1 is sequestered in the nucleoli of rodent trophoblast stem (TS) cells by the I-mfa domain-containing protein HICp40 and that this is associated with their ...
Martindill, D, Riley, P
openaire   +2 more sources

Proteomics Analysis of the Nucleolus in Adenovirus-infected Cells

Molecular & Cellular Proteomics, 2010
Adenoviruses replicate primarily in the host cell nucleus, and it is well established that adenovirus infection affects the structure and function of host cell nucleoli in addition to coding for a number of nucleolar targeted viral proteins. Here we used unbiased proteomics methods, including high throughput mass spectrometry coupled with stable ...
Lam, Yun W., Evans, Vanessa C., Heesom, Kate J., Lamond, Angus I., Matthews, David A.   +4 more
openaire   +3 more sources

THE ORGANIZATION OF THE NUCLEOLUS IN MERISTEMATIC PLANT CELLS [PDF]

The Journal of Cell Biology, 1969
The architecture of the nucleolus in Allium porum and Triticum vulgare meristematic cells has been investigated by means of digestions with various enzymes. After staining with azure B at pH4, plant nucleoli exhibit lighter regions which, under electron microscopy, correspond to the fibrillar zones characterizing these organelles. Evidence is presented
A. Lord, J.-G. Lafontaine
openaire   +1 more source

Identification and characterization of a novel non-structural protein of bluetongue virus [PDF]

, 2011
Bluetongue virus (BTV) is the causative agent of a major disease of livestock (bluetongue). For over two decades, it has been widely accepted that the 10 segments of the dsRNA genome of BTV encode for 7 structural and 3 non-structural proteins.
Rixon, F., Palmarini, M., Ratinier Maxime, Ratinier, Maxime, Golder, Matthew, Nunes, S.F., Alessia Armezzani, Sandro Filipe Nunes, Kathryn Allan, Allan Kathryn, Allan, K., Rixon, Frazer, Golder, M., Allan, Kathryn, Nunes Sandro Filipe, Frazer Rixon, Bayoumy, Amr, Shaw, A., Matthew Golder, Franzoni, G., Caporale Marco, Giulia Franzoni, Golder Matthew, Nunes, Sandro Filipe, Bayoumy Amr, Shaw, Andrew, Amr Bayoumy, Palmarini Massimo, Armezzani, A., Shaw Andrew, Palmarini, Massimo, Ratinier, M., Armezzani, Alessia, Franzoni Giulia, Franzoni, Giulia, Maxime Ratinier, Andrew Shaw, Rixon Frazer, Marco Caporale, Massimo Palmarini, Armezzani Alessia, Bayoumy, A., Caporale, Marco, Caporale, M.   +43 more
core   +1 more source

EBP2, a novel NPM‐ALK‐interacting protein in the nucleolus, contributes to the proliferation of ALCL cells by regulating tumor suppressor p53

Molecular Oncology, 2021
The oncogenic fusion protein nucleophosmin‐anaplastic lymphoma kinase (NPM‐ALK), found in anaplastic large‐cell lymphoma (ALCL), localizes to the cytosol, nucleoplasm, and nucleolus.
Yuki Uchihara, Kenji Tago, Hiroomi Tamura, Megumi Funakoshi‐Tago   +3 more
doaj   +1 more source

SITES OF NUCLEOLUS PRODUCTION IN CULTURED CHINESE HAMSTER CELLS [PDF]

The Journal of Cell Biology, 1969
Chinese hamster cell strains in the early passages in culture display wide variation in number of nucleolus-like bodies per cell, though such strains are characteristically euploid. A variety of criteria indicate that the nucleolus-like bodies are true nucleoli. Their Azure B- and fast green-staining properties indicate the presence of RNA and protein;
S G, Phillips, D M, Phillips
openaire   +2 more sources