Results 31 to 40 of about 441,437 (348)
Origins of Cell Polarity [PDF]
Cell, 1996 The authors thank Kathryn Ayscough, Ken Beck, Fred Chang, Yih-Tai Chen, Kent Grindstaff, and Jeremy Thorner for comments on the manuscript as well as colleagues who kindly provided preprints.
Drubin, David G, Nelson, W.James
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Junctional Adhesion Molecules (JAMs): The JAM-Integrin Connection
Cells, 2018 Junctional adhesion molecules (JAMs) are cell surface adhesion receptors of the immunoglobulin superfamily. JAMs are involved in a variety of biological processes both in the adult organism but also during development.
Daniel Kummer, Klaus Ebnet
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Nature Communications, 2016 Defects in non-canonical Wnt/planar cell polarity signalling have recently been linked to breast cancer aggressiveness. Puvirajesinghe et al. identify VANGL2, p62/SQSTM1 and JNK as important players in this pathway which may be amenable to therapeutic ...
Tania M. Puvirajesinghe +21 more
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Tyrosine-Based Signals Regulate the Assembly of Daple⋅PARD3 Complex at Cell-Cell Junctions. [PDF]
, 2020 Polarized distribution of organelles and molecules inside a cell is vital for a range of cellular processes and its loss is frequently encountered in disease.
Choi, Julie +6 more
core
The SNARE Protein Syntaxin 3 Confers Specificity for Polarized Axonal Trafficking in Neurons. [PDF]
, 2016 Cell polarity and precise subcellular protein localization are pivotal to neuronal function. The SNARE machinery underlies intracellular membrane fusion events, but its role in neuronal polarity and selective protein targeting remain unclear.
Albertolle, Mary E +7 more
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aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability
Nature Communications, 2018 The cell polarity regulator aPKC is associated with cell proliferation but the precise mechanism are unknown. Here, the authors find that aPKC lambda phosphorylates the FoxO1 transcription factor, a gatekeeper of endothelial growth, during both ...
Meghan Riddell +21 more
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Influence of the Polarity of the Electric Field on Electrorheometry [PDF]
, 2019 Uniaxial extensional flow is a canonical flow typically used in rheological characterization to provide complementary information to that obtained by imposing simple shear flow.
Galindo Rosales, Francisco J. +2 more
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Cell Polarity: Getting the PARty Started [PDF]
Current Biology, 2019 Polarity establishment is a key developmental process, but what determines its timing is poorly understood. New research in Caenorhabditis elegans demonstrates that the PAR polarity system extensively reconfigures before becoming competent to polarize. By inhibiting membrane localization of anterior PAR proteins, AIR-1 (aurora A) and PLK-1 (polo kinase)
Boxem, Mike, van den Heuvel, Sander
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TissueMiner: A multiscale analysis toolkit to quantify how cellular processes create tissue dynamics
eLife, 2016 Segmentation and tracking of cells in long-term time-lapse experiments has emerged as a powerful method to understand how tissue shape changes emerge from the complex choreography of constituent cells.
Raphaël Etournay +8 more
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Cell polarity: cell type-specific regulators, common pathways, and polarized vesicle transport. [PDF]
LeukemiaCell polarity, the asymmetric organization of cellular components, is evolutionarily conserved from unicellular and multicellular organisms and is crucial for many biological processes. Polarity is required to maintain cell and tissue integrity by regulating cell division, migration, orientation, cell-cell interactions, and morphogenesis.
Bera S, Loeffler D.
europepmc +3 more sources