Results 41 to 50 of about 433,759 (305)

Influence of the Polarity of the Electric Field on Electrorheometry [PDF]

open access: yes, 2019
Uniaxial extensional flow is a canonical flow typically used in rheological characterization to provide complementary information to that obtained by imposing simple shear flow.
Galindo Rosales, Francisco J.   +2 more
core   +1 more source

Cell Polarity: Centrosomes Release Signals for Polarization [PDF]

open access: yesCurrent Biology, 2012
New findings reveal that, in Caenorhabditis elegans embryos, the centrosome provides signals that induce cell polarization, independently of its function as the microtubule-organizing center.
Sumiyoshi, Eisuke, Sugimoto, Asako
openaire   +2 more sources

Modeling Heterogeneity of Triple‐Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance

open access: yesAdvanced Science, 2021
Triple‐negative breast cancer (TNBC) is a highly aggressive breast cancer subtype characterized by a remarkable molecular heterogeneity. Currently, there are no effective druggable targets and advanced preclinical models of the human disease.
Fabienne Lamballe   +16 more
doaj   +1 more source

Polarity in immune cells

open access: yes, 2023
Immune cells are responsible for pathogen detection and elimination, as well as for signaling to other cells the presence of potential danger. In order to mount an efficient immune response, they need to move and search for a pathogen, interact with other cells, and diversify the population by asymmetric cell division.
Pineau, Judith   +3 more
openaire   +2 more sources

Cell polarity: Par for the polar course [PDF]

open access: yesCurrent Biology, 1997
The nematode PAR-1 gene is required for asymmetric cell divisions during development. Recently identified mammalian Par-1 homologues are kinases that phosphorylate microtubule-associated proteins; their overexpression disrupts the microtubule cytoskeleton, and alters cellular structure and organization.
Nelson, W.James, Grindstaff, Kent K.
openaire   +2 more sources

Active Inter-cellular Forces in Collective Cell Motility

open access: yes, 2020
The collective behaviour of confluent cell sheets is strongly influenced both by polar forces, arising through cytoskeletal propulsion and by active inter-cellular forces, which are mediated by interactions across cell-cell junctions.
Doostmohammadi, Amin   +3 more
core   +1 more source

Planar Cell Polarity: Coordinating Morphogenetic Cell Behaviors with Embryonic Polarity [PDF]

open access: yesDevelopmental Cell, 2011
Planar cell polarization entails establishment of cellular asymmetries within the tissue plane. An evolutionarily conserved planar cell polarity (PCP) signaling system employs intra- and intercellular feedback interactions between its core components, including Frizzled, Van Gogh, Flamingo, Prickle, and Dishevelled, to establish their characteristic ...
Gray, Ryan S.   +2 more
openaire   +2 more sources

Whole carcass diets: a role for fibre in gastrointestinal health of cheetahs? [PDF]

open access: yes, 2011
This study was undertaken to test the hypothesis that altered podocyte slit protein nephrin distribution is associated with disturbed polarity protein expressions in podocytes from preeclampsia (PE).
Depauw, Sarah   +6 more
core   +2 more sources

Mechanobiology of the nucleus during the G2-M transition

open access: yesNucleus
Cellular behavior is continuously influenced by mechanical forces. These forces span the cytoskeleton and reach the nucleus, where they trigger mechanotransduction pathways that regulate downstream biochemical events.
Joana T. Lima, Jorge G. Ferreira
doaj   +1 more source

Digenic inheritance of mutations in EPHA2 and SLC26A4 in Pendred syndrome

open access: yesNature Communications, 2020
While biallelic mutations of the SLC26A4 gene cause non-syndromic hearing loss with enlarged vestibular aqueducts or Pendred syndrome, a considerable number of patients carry mono-allelic mutations.
Mengnan Li   +21 more
doaj   +1 more source

Home - About - Disclaimer - Privacy