Results 41 to 50 of about 220,716 (312)

Regulation of cell migration by dynamic microtubules [PDF]

, 2011
Microtubules define the architecture and internal organization of cells by positioning organelles and activities, as well as by supporting cell shape and mechanics. One of the major functions of microtubules is the control of polarized cell motility.
Irina Kaverina, Anne Straube, Kaverina, Irina, Straube, Anne   +3 more
core   +1 more source

Normalized Polarization Ratios for the Analysis of Cell Polarity

PLoS ONE, 2014
The quantification and analysis of molecular localization in living cells is increasingly important for elucidating biological pathways, and new methods are rapidly emerging. The quantification of cell polarity has generated much interest recently, and ratiometric analysis of fluorescence microscopy images provides one means to quantify cell polarity ...
Shimoni, R, Pham, K, Yassin, M, Ludford-Menting, MJ, Gu, M, Russell, SM   +5 more
openaire   +5 more sources

Cell-cell Interaction, Cell Polarity, And The Blood-testis Barrier

, 2015
The study of polarity and its role in cell–cell interactions, such as spermatid polarity and adhesion in the seminiferous epithelium, and blood–testis barrier (BTB) in the testis during the epithelial cycle of spermatogenesis in recent years has yielded ...
Dolores D. Mruk, C. Yan Cheng, Will M. Lee, Tang, EIY, Lee, WWM, Cheng, CY, Mruk, DD, Elizabeth I. Tang   +7 more
core   +1 more source

Generation and regulation of microtubule network asymmetry to drive cell polarity

, 2020
Microtubules control cell architecture by serving as a scaffold for intracellular transport, signaling, and organelle positioning. Microtubules are intrinsically polarized, and their orientation, density, and post-translational modifications both respond
Meiring, Joyce C.M., Sub Cell Biology, Celbiologie, Shneyer, Boris I., Akhmanova, Anna   +4 more
core   +1 more source

Activation of polarized cell growth by inhibition of cell polarity [PDF]

, 2018
Abstract A key feature of cells is the capacity to activate new functional polarized domains contemporaneously to pre-existing ones. How cells accomplish this is not clear. Here, we show that in fission yeast inhibition of cell polarity at pre-existing domains of polarized cell growth is required to activate new growth.
Geymonat, Marco, Chessel, Anatole, Dodgson, James, Punter, Hannah, Horns, Felix, Nagy, Attila Csikász, Carazo Salas, Rafael Edgardo   +6 more
openaire   +1 more source

Epidermal growth factor signalling controls Myosin II planar polarity to orchestrate convergent extension movements during Drosophila tubulogenesis

, 2014
Aditya Saxena was funded by the Cambridge Commonwealth Trust. Barry Denholm was funded by Kidney Research UK PDF1/2010. Stephanie Bunt was funded by The Rae and Edith Bennett Travelling Scholarship and John Stanley Gardiner Trust Fund.
Krishnaswamy VijayRaghavan, Helen Skaer, Barry Denholm. ¤b, Aditya Saxena. ¤a, Barry Denholm, Krishnaswamy Vijayraghavan Helen, Stephanie Bunt, Bunt, Stephanie, Skaer, Helen, VijayRaghavan, Krishnaswamy, Aditya Saxena, Marcus Bischoff, Bischoff, Marcus, Saxena, Aditya, Denholm, Barry   +14 more
core   +1 more source

Modeling Heterogeneity of Triple‐Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance

Advanced Science, 2021
Triple‐negative breast cancer (TNBC) is a highly aggressive breast cancer subtype characterized by a remarkable molecular heterogeneity. Currently, there are no effective druggable targets and advanced preclinical models of the human disease.
Fabienne Lamballe, Fahmida Ahmad, Yaron Vinik, Olivier Castellanet, Fabrice Daian, Anna‐Katharina Müller, Ulrike A. Köhler, Anne‐Laure Bailly, Emmanuelle Josselin, Rémy Castellano, Christelle Cayrou, Emmanuelle Charafe‐Jauffret, Gordon B. Mills, Vincent Géli, Jean‐Paul Borg, Sima Lev, Flavio Maina   +16 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

A direct interaction of JAM-C with the tight junction scaffold protein ZO-2

Scientific Reports
Tight junctions are sites of cell-cell contacts at the apical region of epithelial junctions that are involved in barrier formation, cellular signaling, and cell-cell adhesion.
Annika Schulte, Mariel F. Schwietzer, Frauke Brinkmann, Valentin Teuber, Sandra Citi, Mikio Furuse, Michel Aurrand-Lions, Klaus Ebnet   +7 more
doaj   +1 more source

Mechanobiology of the nucleus during the G2-M transition

Nucleus
Cellular behavior is continuously influenced by mechanical forces. These forces span the cytoskeleton and reach the nucleus, where they trigger mechanotransduction pathways that regulate downstream biochemical events.
Joana T. Lima, Jorge G. Ferreira
doaj   +1 more source