Results 61 to 70 of about 220,716 (312)
Planar Cell Polarity: Coordinating Morphogenetic Cell Behaviors with Embryonic Polarity [PDF]
Developmental Cell, 2011 Planar cell polarization entails establishment of cellular asymmetries within the tissue plane. An evolutionarily conserved planar cell polarity (PCP) signaling system employs intra- and intercellular feedback interactions between its core components, including Frizzled, Van Gogh, Flamingo, Prickle, and Dishevelled, to establish their characteristic ...
Gray, Ryan S. +2 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
A systems biology approach to multi-scale modelling and analysis of planar cell polarity in drosophila melanogaster wing [PDF]
, 2013 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Systems biology aims to describe and understand biology at a global scale where biological systems function as a result of complex mechanisms that happen at
Gao, Qian
core
The apical submembrane cytoskeleton participates in the organization of the apical pole in epithelial cells [PDF]
, 1997 In a previous publication (Rodriguez, M.L., M. Brignoni, and P.J.I. Salas. 1994. J. Cell Sci. 107: 3145-3151), we described the existence of a terminal web-like structure in nonbrush border cells, which comprises a specifically apical cytokeratin ...
Ana L. Viciana +14 more
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Balancing cell polarity PARts through dephosphorylation [PDF]
, 2022 How cells spatially organize their plasma membrane, cytoskeleton, and cytoplasm remains a central question for cell biologists. In this issue of JCB, Calvi et al. (2022. J. Cell Biol.
Barros-Carvalho, A, Morais-de-Sá, E
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Autonomous epithelial folding induced by an intracellular mechano-polarity feedback loop.
PLoS Computational Biology, 2021 Epithelial tissues form folded structures during embryonic development and organogenesis. Whereas substantial efforts have been devoted to identifying mechanical and biochemical mechanisms that induce folding, whether and how their interplay ...
Fu-Lai Wen +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The distribution of Dishevelled in convergently extending mesoderm [PDF]
, 2013 Convergent extension (CE) is a conserved morphogenetic movement that drives axial lengthening of the primary body axis and depends on the planar cell polarity (PCP) pathway.
Panousopoulou, Eleni +7 more
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Deciphering the roles of cell shape and Fat and Dachsous planar polarity in arranging the Drosophila apical microtubule network through quantitative image analysis [PDF]
, 2023 In epithelial cells, planar polarisation of subapical microtubule networks is thought to be important for both breaking cellular symmetry and maintaining the resulting cellular polarity.
Hunton, Robert +15 more
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Cell polarity: mechanochemical patterning
Trends in Cell Biology, 2013 Nearly every cell type exhibits some form of polarity, yet the molecular mechanisms vary widely. Here we examine what we term 'chemical systems' where cell polarization arises through biochemical interactions in signaling pathways, 'mechanical systems' where cells polarize due to forces, stresses and transport, and 'mechanochemical systems' where ...
Nathan W. Goehring, Stephan W. Grill
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