Results 51 to 60 of about 433,759 (305)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A safeguard mechanism regulates Rho GTPases to coordinate cytokinesis with the establishment of cell polarity. [PDF]
PLoS Biology, 2013 The spatiotemporal control of cell polarity is crucial for the development of multicellular organisms and for reliable polarity switches during cell cycle progression in unicellular systems.
Franz Meitinger +5 more
doaj +1 more source
Spatio-temporal dynamics of an active, polar, viscoelastic ring
, 2014 Constitutive equations for a one-dimensional, active, polar, viscoelastic liquid are derived by treating the strain field as a slow hydrodynamic variable.
Marcq, Philippe
core +2 more sources
Polarized Cells, Polarized Views: Asymmetric Cell Division in Hematopoietic Cells [PDF]
Frontiers in Immunology, 2014 It has long been recognized that alterations in cell shape and polarity play important roles in coordinating lymphocyte functions. In the last decade, a new aspect of lymphocyte polarity has attracted much attention, termed asymmetric cell division (ACD).
Kim ePham +6 more
openaire +4 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Unified quantitative characterization of epithelial tissue development
eLife, 2015 Understanding the mechanisms regulating development requires a quantitative characterization of cell divisions, rearrangements, cell size and shape changes, and apoptoses.
Boris Guirao +8 more
doaj +1 more source
Combined effect of cell geometry and polarity domains determines the orientation of unequal division
eLife, 2021 Cell division orientation is thought to result from a competition between cell geometry and polarity domains controlling the position of the mitotic spindle during mitosis.
Benoit G Godard +3 more
doaj +1 more source
Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation [PDF]
, 2006 The planar cell polarity (PCP) pathway is conserved throughout evolution, but it mediates distinct developmental processes. In Drosophila, members of the PCP pathway localize in a polarized fashion to specify the cellular polarity within the plane of the
Brinkman, Brendan C. +9 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Coordinating cell polarity and cell cycle progression: what can we learn from flies and worms? [PDF]
Open Biology, 2013 Spatio-temporal coordination of events during cell division is crucial for animal development. In recent years, emerging data have strengthened the notion that tight coupling of cell cycle progression and cell polarity in dividing cells is crucial for ...
Anna Noatynska +3 more
doaj +1 more source