Results 31 to 40 of about 220,716 (312)
Frontiers in Microbiology, 2022 The C-terminus of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protein E contains a PBM (PDZ-binding motif) targeting PDZ (PSD-95/Dlg/ZO-1) domains, which is identical to the PBM of SARS-CoV.
Yanlei Zhu +9 more
doaj +1 more source
Cell Migration with Multiple Pseudopodia: Temporal and Spatial Sensing Models [PDF]
, 2013 Cell migration triggered by pseudopodia (or “false feet”) is the most used method of locomotion. A 3D finite element model of a cell migrating over a 2D substrate is proposed, with a particular focus on the mechanical aspects of the biological phenomenon.
ALLENA, Rachele
core +1 more source
Cell polarity and PIN protein positioning in Arabidopsis requie STEROL METHYLTRANSFERASE1 function [PDF]
, 2003 Plants have many polarized cell types, but relatively little is known about the mechanisms that establish polarity. The orc mutant was identified originally by defects in root patterning, and positional cloning revealed that the affected gene encodes ...
Friml, Jirí +12 more
core +1 more source
The coordination of cell growth during fission yeast mating requires Ras1-GTP hydrolysis [PDF]
, 2013 The spatial and temporal control of polarity is fundamental to the survival of all organisms. Cells define their polarity using highly conserved mechanisms that frequently rely upon the action of small GTPases, such as Ras and Cdc42.
Ladds, Graham +15 more
core +1 more source
aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability
Nature Communications, 2018 The cell polarity regulator aPKC is associated with cell proliferation but the precise mechanism are unknown. Here, the authors find that aPKC lambda phosphorylates the FoxO1 transcription factor, a gatekeeper of endothelial growth, during both ...
Meghan Riddell +21 more
doaj +1 more source
Junctional Adhesion Molecules (JAMs): The JAM-Integrin Connection
Cells, 2018 Junctional adhesion molecules (JAMs) are cell surface adhesion receptors of the immunoglobulin superfamily. JAMs are involved in a variety of biological processes both in the adult organism but also during development.
Daniel Kummer, Klaus Ebnet
doaj +1 more source
Nature Communications, 2016 Defects in non-canonical Wnt/planar cell polarity signalling have recently been linked to breast cancer aggressiveness. Puvirajesinghe et al. identify VANGL2, p62/SQSTM1 and JNK as important players in this pathway which may be amenable to therapeutic ...
Tania M. Puvirajesinghe +21 more
doaj +1 more source
Neuronal polarity: remodeling microtubule organization [PDF]
, 2016 Cell polarization generates morphological and functional asymmetry, and is crucial for the development and proper functioning of many cell types. Recent data have revealed that the microtubule cytoskeleton is a major determinant in the establishment and ...
Sub Cell Biology +3 more
core +1 more source
Coronaviruses in Polarized Epithelial Cells [PDF]
, 1995 Coronaviruses have a marked tropism for epithelial cells. In this paper the interactions of the porcine transmissible gastroenteritis virus (TGEV) and mouse hepatitis virus (MHV-A59) with epithelial cells are compared. Porcine (LLC-PK1) and murine (mTAL) epithelial cells were grown on permeable supports.
Horzinek, M.C. +6 more
openaire +5 more sources
TissueMiner: A multiscale analysis toolkit to quantify how cellular processes create tissue dynamics
eLife, 2016 Segmentation and tracking of cells in long-term time-lapse experiments has emerged as a powerful method to understand how tissue shape changes emerge from the complex choreography of constituent cells.
Raphaël Etournay +8 more
doaj +1 more source