Results 21 to 30 of about 433,759 (305)
Cadherin-26 (CDH26) regulates airway epithelial cell cytoskeletal structure and polarity. [PDF]
, 2018 Polarization of the airway epithelial cells (AECs) in the airway lumen is critical to the proper function of the mucociliary escalator and maintenance of lung health, but the cellular requirements for polarization of AECs are poorly understood.
Fahy, John V +8 more
core +3 more sources
Annual Review of Cell and Developmental Biology, 2017 A conserved molecular machinery centered on the Cdc42 GTPase regulates cell polarity in diverse organisms. Here we review findings from budding and fission yeasts that reveal both a conserved core polarity circuit and several adaptations that each organism exploits to fulfill the needs of its lifestyle.
Jian-Geng, Chiou +2 more
openaire +2 more sources
Mechanics and polarity in cell motility [PDF]
, 2016 The motility of a fish keratocyte on a flat substrate exhibits two distinct regimes: the non-migrating and the migrating one. In both configurations the shape is fixed in time and, when the cell is moving, the velocity is constant in magnitude and ...
Ambrosi, Davide, Zanzottera, Anna
core +2 more sources
Cell polarity: mechanochemical patterning
Trends in Cell Biology, 2013 Nearly every cell type exhibits some form of polarity, yet the molecular mechanisms vary widely. Here we examine what we term 'chemical systems' where cell polarization arises through biochemical interactions in signaling pathways, 'mechanical systems' where cells polarize due to forces, stresses and transport, and 'mechanochemical systems' where ...
Nathan W. Goehring, Stephan W. Grill
openaire +5 more sources
Biomolecules, 2019 Drosophila Schneider 2 (S2) cells are a simple and powerful system commonly used in cell biology because they are well suited for high resolution microscopy and RNAi-mediated depletion.
Mariana Osswald +2 more
doaj +1 more source
Mechanisms of cell polarization [PDF]
Current Opinion in Systems Biology, 2017 Cell polarization is a key step in the migration, development, and organization of eukaryotic cells, both at the single cell and multicellular level. Research on the mechanisms that give rise to polarization of a given cell, and organization of polarity within a tissue has led to new understanding across cellular and developmental biology.
Wouter-Jan, Rappel +1 more
openaire +2 more sources
Editorial overview: Membrane traffic and cell polarity [PDF]
, 2016 No abstract ...
Bryant, David M., Yap, Alpha S.
core +1 more source
Frontiers in Microbiology, 2022 The C-terminus of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protein E contains a PBM (PDZ-binding motif) targeting PDZ (PSD-95/Dlg/ZO-1) domains, which is identical to the PBM of SARS-CoV.
Yanlei Zhu +9 more
doaj +1 more source
Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation [PDF]
, 2017 Cell proliferation has generally been considered dispensable for anteroposterior extension of embryonic axis during vertebrate gastrulation. Signal transducer and activator of transcription 3 (Stat3), a conserved controller of cell proliferation ...
Liu, Yinzi +2 more
core +4 more sources