Results 61 to 70 of about 441,437 (348)

Autonomous epithelial folding induced by an intracellular mechano-polarity feedback loop.

open access: yesPLoS Computational Biology, 2021
Epithelial tissues form folded structures during embryonic development and organogenesis. Whereas substantial efforts have been devoted to identifying mechanical and biochemical mechanisms that induce folding, whether and how their interplay ...
Fu-Lai Wen   +3 more
doaj   +1 more source

Spatio-temporal dynamics of an active, polar, viscoelastic ring

open access: yes, 2014
Constitutive equations for a one-dimensional, active, polar, viscoelastic liquid are derived by treating the strain field as a slow hydrodynamic variable.
Marcq, Philippe
core   +2 more sources

Cadherin-26 (CDH26) regulates airway epithelial cell cytoskeletal structure and polarity. [PDF]

open access: yes, 2018
Polarization of the airway epithelial cells (AECs) in the airway lumen is critical to the proper function of the mucociliary escalator and maintenance of lung health, but the cellular requirements for polarization of AECs are poorly understood.
Fahy, John V   +8 more
core   +3 more sources

Polarized Cells, Polarized Views: Asymmetric Cell Division in Hematopoietic Cells [PDF]

open access: yesFrontiers in Immunology, 2014
It has long been recognized that alterations in cell shape and polarity play important roles in coordinating lymphocyte functions. In the last decade, a new aspect of lymphocyte polarity has attracted much attention, termed asymmetric cell division (ACD).
Kim ePham   +6 more
openaire   +4 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Modulation of sterol homeostasis by the Cdc42p effectors Cla4p and Ste20p in the yeast Saccharomyces cerevisiae [PDF]

open access: yes, 2009
This article is available open access through the publisher’s website at the link below. Copyright @ 2009 The Authors.The conserved Rho-type GTPase Cdc42p is a key regulator of signal transduction and polarity in eukaryotic cells.
Daum, G   +4 more
core   +1 more source

Cell Polarity Signaling: Focus on Polar Auxin Transport [PDF]

open access: yesMolecular Plant, 2008
Polar auxin transport, which is required for the formation of auxin gradients and directional auxin flows that are critical for plant pattern formation, morphogenesis, and directional growth response to vectorial cues, is mediated by polarized sub-cellular distribution of PIN-FORMED Proteins (PINs, auxin efflux carriers), AUX1/AUX1-like proteins (auxin
Gao, Xiaowei   +3 more
openaire   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Multiple State Representation Scheme for Organic Bulk Heterojunction Solar Cells: A Novel Analysis Perspective

open access: yes, 2013
The physics of organic bulk heterojunction solar cells is studied within a six state model, which is used to analyze the factors that affect current-voltage characteristics, power-voltage properties and efficiency, and their dependence on nonradiative ...
Dierl, Marcel   +3 more
core   +1 more source

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