Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis
Journal of Cell Biology, 2022 Eskandari and Eaves review evidence of caspase-3-regulated protein quality, proliferation, differentiation, and tumorigenic activity in viable cells.
E. Eskandari, C. Eaves
semanticscholar +1 more source
The Chemokine Receptor CXCR4 in Cell Proliferation and Tissue Regeneration
Frontiers in Immunology, 2020 The CXCR4 receptor upon binding its ligands triggers multiple signaling pathways that orchestrate cell migration, hematopoiesis and cell homing, and retention in the bone marrow.
M. Bianchi, R. Mezzapelle
semanticscholar +1 more source
A characterization of four B16 murine melanoma cell sublines molecular fingerprint and proliferation behavior [PDF]
, 2013 Background: One of the most popular and versatile model of murine melanoma is by inoculating B16 cells in the syngeneic C57BL6J mouse strain. A characterization of different B16 modified cell sub-lines will be of real practical interest.
Barbu-Tudoran, Lucian +8 more
core +1 more source
BMC Cancer, 2019 Background S100A8 and S100A9, two heterodimer-forming members of the S100 family, aberrantly express in a variety of cancer types. However, little is known about the mechanism that regulates S100A8/S100A9 co-expression in cancer cells.
Yunguang Li +7 more
doaj +1 more source
Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation [PDF]
, 1993 We have constructed a soluble chimeric fusion protein between the mouse CD8 alpha chain and the mouse CD40 T cell ligand. This protein binds to both human and mouse B cells.
Brocker, Thomas +5 more
core +1 more source
Journal of Immunology, 1984 The monoclonal antibody Ki-67 detects a nuclear antigen that is present only in proliferating cells. The aim of the present investigation was to clarify whether the Ki-67 nuclear antigen is restricted in its expression to certain phases of the cell cycle.
J. Gerdes +5 more
semanticscholar +1 more source
Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer. [PDF]
, 2017 Tumors adapt to an unfavorable microenvironment by controlling the balance between cell proliferation and cell motility, but the regulators of this process are largely unknown.
Ashani T. Weeraratna +17 more
core +2 more sources
Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways
Cancers, 2017 The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is commonly upregulated in cancers such as in non-small-cell lung cancer, metastatic colorectal cancer, glioblastoma, head and neck cancer, pancreatic cancer, and breast ...
Ping Wee, Zhixiang Wang
semanticscholar +1 more source
Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease
BMC Genomics, 2018 Background Congenital heart disease (CHD) is the leading non-infectious cause of death in infants. Monozygotic (MZ) twins share nearly all of their genetic variants before and after birth.
Guoliang Lyu +11 more
doaj +1 more source
The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line. [PDF]
, 2011 The voltage gated potassium (K+) channels Eag and HERG have been implicated in the pathogenesis of various cancers, through association with cell cycle changes and programmed cell death.
Anish Bali +6 more
core +5 more sources