Results 31 to 40 of about 15,022,196 (353)

Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways

open access: yesCancers, 2017
The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is commonly upregulated in cancers such as in non-small-cell lung cancer, metastatic colorectal cancer, glioblastoma, head and neck cancer, pancreatic cancer, and breast ...
Ping Wee, Zhixiang Wang
semanticscholar   +1 more source

A characterization of four B16 murine melanoma cell sublines molecular fingerprint and proliferation behavior [PDF]

open access: yes, 2013
Background: One of the most popular and versatile model of murine melanoma is by inoculating B16 cells in the syngeneic C57BL6J mouse strain. A characterization of different B16 modified cell sub-lines will be of real practical interest.
Barbu-Tudoran, Lucian   +8 more
core   +1 more source

Skin Cell Proliferation Stimulated by Microneedles [PDF]

open access: yes, 2012
A classical wound may be defined as a disruption of tissue integrity. Wounds, caused by trauma from accidents or surgery, that close via secondary intention rely on the biological phases of healing, i.e., hemostasis, inflammation, proliferation, and ...
Kloth, Luther C., Liebl, Horst
core   +2 more sources

Differential Regulation of Growth-Promoting Signalling Pathways by E-Cadherin [PDF]

open access: yes, 2010
Background: Despite the well-documented association between loss of E-cadherin and carcinogenesis, as well as the link between restoration of its expression and suppression of proliferation in carcinoma cells, the ability of E-cadherin to modulate growth-
Dawn C. Walker   +4 more
core   +7 more sources

A Drosophila RNAi library modulates Hippo pathway-dependent tissue growth

open access: yesNature Communications, 2016
Drosophila RNAi libraries are commonly used to perform large-scale functional genetics screens in vivo. Here the authors find that a subset of lines from the VDRC KK RNAi line cause false-positive enhancement of the Hippo pathway, and provide a strain ...
Joseph H.A. Vissers   +3 more
doaj   +1 more source

Genome and epigenome analysis of monozygotic twins discordant for congenital heart disease

open access: yesBMC Genomics, 2018
Background Congenital heart disease (CHD) is the leading non-infectious cause of death in infants. Monozygotic (MZ) twins share nearly all of their genetic variants before and after birth.
Guoliang Lyu   +11 more
doaj   +1 more source

Actomyosin and CSI1/POM2 cooperate to deliver cellulose synthase from Golgi to cortical microtubules in Arabidopsis

open access: yesNature Communications, 2023
As one of the major components of plant cell walls, cellulose is crucial for plant growth and development. Cellulose is synthesized by cellulose synthase (CesA) complexes (CSCs), which are trafficked and delivered from the Golgi apparatus to the plasma ...
Lu Liu   +7 more
doaj   +1 more source

Surface topography of hydroxyapatite affects ROS17/2.8 cells response [PDF]

open access: yes, 2002
Hydroxyapatite (HA) has been used in orthopedic, dental, and maxillofacial surgery as a bone substitute. The aim of this investigation was to study the effect of surface topography produced by the presence of microporosity on cell response, evaluating ...
Adalberto Luiz Rosa   +27 more
core   +4 more sources

The Role of Exogenous Stresses on the Proliferation of Intervertebral Disk Cells

open access: yesGlobal Spine Journal, 2012
Introduction The native microenvironment of intervertebral disk (IVD) cells is characterized by adverse physicochemical conditions. Low cellularity and proliferation rate is a hallmark of the disk, possibly resulting from the absence of vascularization ...
A. Dimozi   +3 more
doaj   +1 more source

FXR Regulates Intestinal Cancer Stem Cell Proliferation.

open access: yesCell, 2019
Increased levels of intestinal bile acids (BAs) are a risk factor for colorectal cancer (CRC). Here, we show that the convergence of dietary factors (high-fat diet) and dysregulated WNT signaling (APC mutation) alters BA profiles to drive malignant ...
T. Fu   +19 more
semanticscholar   +1 more source

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