Sox2 maintains epithelial cell proliferation in the successional dental lamina [PDF]
OBJECTIVES: The successional dental lamina is the distinctive structure on the lingual side of the vertebrate tooth germ. The aim of this study was to investigate the relationship among Sox2, Claudin10 and laminin5 and the role of Sox2 in ...
김은정, 정한성
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MAST4 controls cell cycle in spermatogonial stem cells [PDF]
Spermatogonial stem cell (SSC) self-renewal is regulated by reciprocal interactions between Sertoli cells and SSCs in the testis. In a previous study, microtubule-associated serine/threonine kinase 4 (MAST4) has been studied in Sertoli cells as a ...
정한성, 이동준
core +3 more sources
Nucleolin Regulates Pulmonary Artery Smooth Muscle Cell Proliferation under Hypoxia by Modulating miRNA Expression [PDF]
Hypoxia induces the abnormal proliferation of vascular smooth muscle cells (VSMCs), resulting in the pathogenesis of various vascular diseases. RNA-binding proteins (RBPs) are involved in a wide range of biological processes, including cell proliferation
Jihui Lee, Hara Kang
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CD29 of human umbilical cord mesenchymal stem cells is required for expansion of CD34(+) cells [PDF]
ObjectivesHuman umbilical cord mesenchymal stem cells (hUCMSCs) play a critical role in expanding haematopoietic stem cells (HSCs) by providing the essential microenvironment for haematopoiesis.
Yang, Y. +4 more
core +1 more source
Chronic treatment with the GLP1 analogue liraglutide increases cell proliferation and differentiation into neurons in an AD mouse model [PDF]
Neurogenesis is a life long process, but the rate of cell proliferation and differentiation decreases with age. In Alzheimer's patients, along with age, the presence of Aβ in the brain inhibits this process by reducing stem cell proliferation and cell ...
Vadivel Parthsarathy +7 more
core +1 more source
Auxilin regulates intestinal stem cell proliferation through EGFR [PDF]
[[abstract]]Adult tissue homeostasis is maintained by residential stem cells. The proliferation and differentiation of adult stem cells must be tightly balanced to avoid excessive proliferation or premature differentiation.
Zhao, H;Ren, X;Kong, R;Shi, L;Li, Z;Wang, R;Ma, R;Zhao, H;Liu, F;Chang, HC;Chen, CH;Li, Z
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Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes [PDF]
In normal T cell progenitors, phosphoinositide-dependent kinase l (PDK1)-mediated phosphorylation and activation of protein kinase B (PKB) is essential for the phosphorylation and inactivation of Foxo family transcription factors, and also controls T ...
Feijoo, C. +20 more
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MAPK phosphorylation of connexin 43 promotes binding of cyclin E and smooth muscle cell proliferation [PDF]
<p>Rationale: Dedifferentiation of vascular smooth muscle cells (VSMC) leading to a proliferative cell phenotype significantly contributes to the development of atherosclerosis.
Columbus, L. +12 more
core +1 more source
Cell proliferation and cancer.
The discovery that phosphorylation of selected proteins by cyclin-dependent kinases is the engine which makes the cycle run provides a new image of the control of proliferation and of its deregulation. The high conservation of this machinery in the different eukaryotic organisms emphasizes its early origin and its importance for life. It also makes the
Lopez-Saez, J.F. +3 more
openaire +3 more sources
The Role of Exogenous Stresses on the Proliferation of Intervertebral Disk Cells
Introduction The native microenvironment of intervertebral disk (IVD) cells is characterized by adverse physicochemical conditions. Low cellularity and proliferation rate is a hallmark of the disk, possibly resulting from the absence of vascularization ...
A. Dimozi +3 more
doaj +1 more source

