Results 241 to 250 of about 15,022,196 (353)

The effects of LINC00324 on cell proliferation, migration, and invasion via autophagy in melanoma. [PDF]

Sci Rep
Ma S, Liu C, Ding Y, Li M, Wang M, Feng S.   +5 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Apolipoprotein E (APOE) Promotes Cell Proliferation and Invasion in Glioma via the PI3K/AKT Signaling Pathway. [PDF]

Cancer Manag Res
Xia M, Chen K, Chen W, Ren Z, Li X.
europepmc   +1 more source

SerpinB1 Promotes Pancreatic β Cell Proliferation.

Cell Metabolism, 2016
Abdelfattah El Ouaamari, E. Dirice, N. Gedeon, Jiang Hu, Jianying Zhou, J. Shirakawa, Lifei Hou, J. Goodman, Christos Karampelias, G. Qiang, J. Boucher, Rachael Martinez, M. Gritsenko, Dario F. De Jesus, S. Kahraman, S. Bhatt, Richard D. Smith, H. Beer, Prapaporn Jungtrakoon, Y. Gong, A. Goldfine, C. Liew, A. Doria, Olov Andersson, W. Qian, E. Remold-O’Donnell, R. Kulkarni   +26 more
semanticscholar   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

METTL3 regulates Leydig cell proliferation via miR-145-PCK1 mediated gluconeogenesis in goats. [PDF]

J Anim Sci Biotechnol
Tang W, Cao M, Qiao F, Luo J, Ju Y, Wang X, An P, Sun W, Chen X.   +8 more
europepmc   +1 more source

Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation

Science, 2012
Mohit M. Jain, R. Nilsson, Sonia Sharma, Nikhil Madhusudhan, T. Kitami, Amanda L. Souza, Ran Kafri, M. Kirschner, C. Clish, V. Mootha   +9 more
semanticscholar   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

[Retracted] MicroRNA-34a suppresses breast cancer cell proliferation and invasion by targeting Notch1. [PDF]

Exp Ther Med
Rui X, Zhao H, Xiao X, Wang L, Mo L, Yao Y.   +5 more
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source